Perceptions of a Health Care Notebook from Female Breast Cancer Survivors with Cognitive Impairment.

Strengthening communication between providers and patients, especially those with cognitive impairment, is required given care complexity and fragmentation across the care continuum. Therefore, determining patient perceptions about the Siebens Health Care Notebook (SHCN), a tool to support self-management and strengthen communication and care continuity, is fundamental to understanding SHCN usability. Participants were breast cancer survivors in a study evaluating a 6-week cognitive rehabilitation program, who reported cancer-related cognitive impairment (Functional Assessment of Cancer Therapy-Cognitive Function-Perceived Cognitive Impairment (PCI) subscale < 59). Participant groups were alternately assigned to receive the SHCN (intervention) or not (control). SHCN recipients completed a 3-item qualitative perception survey at program completion. Both groups were surveyed at baseline, program completion, and 4 weeks later about communication with physicians. Scores were compared using Wilcoxon rank-sum tests. No baseline demographic or PCI score differences occurred between intervention (n = 29) and control (n = 16) groups. Of 22 (76%) who completed the SHCN perception survey, 100% endorsed it as useful in tracking health information, as helpful, and would recommend it to others. No group differences in communication activities with physicians were demonstrated. Women reporting cognitive impairment after breast cancer treatment perceived the SHCN as a beneficial self-care tool and would suggest it to others. Communication activities with physicians did not change during the study's short duration. Future research is needed to evaluate SHCN features contributing to helpfulness and details on use, including two-way communication activities between patients and physicians, across the care continuum.

Selective Cu and Ni-MOFs as pre-catalysts for the hydrogenation of furfural to furfuryl alcohol.

In this work, we report the design of one-dimensional (1D) metal-organic framework containing Cu(II) and Ni(II) active sites using a N,N'-bis-(4-pyridyl)isophthalamide linker to form MOF 1 [Cu1/2(L1)(NO3-)·DMF] and MOF 2 [Ni1/2L1Cl]. The MOFs were evaluated as heterogeneous catalysts for the hydrogenation of furfural to furfuryl alcohol. MOF 2 catalyst showed impressive performance with conversion of FF (81%) and selectivity towards FA (100%). Post-experimental characterisation showed that the structural integrity of the MOF 2 was not altered after catalysis. The catalyst could also be reused several times without any significant loss in activity and selectivity. Furthermore, a possible plausible reaction mechanism of the reaction over MOF 2 was proposed.