Dietary intake of Nova Scotia youth in grades 7 and 11.

PURPOSE: We examined dietary intakes among Nova Scotia youth, and analyzed whether these intakes met existing dietary guidelines. METHODS: Data from 1469 students in grades 7 and 11 from randomly selected schools were collected via a web-based dietary assessment tool, including a 24-hour recall. Nutrient analysis products were subjected to descriptive and inferential statistical analyses. RESULTS: Reported dietary intakes across sexes and grades showed the vast majority of youth did not meet minimum recommendations for fibre (96% to 98%) or vegetable and fruit servings (83.3% to 90.7%). Girls in grade 11 reported greater intakes of folate and lower intakes of saturated fat, and were less likely to report iron intakes at or above the Estimated Average Requirement than were grade 7 girls. Across ages, more than 75% of girls reported low calcium and folate intakes. Boys in both grades reported consuming more energy than did girls, and older boys reported consuming more than did younger boys. Foods outside the four main food groups contributed about 25% of total reported energy intake. Students in grade 7 consumed pop, salty snacks, and french fries more frequently than did students in grade 11. CONCLUSIONS: Adolescents' self-reported dietary intakes may not meet current dietary recommendations. Continued efforts are needed to develop innovative strategies to ensure healthy eating patterns.

The impact of a short-period head-down tilt on executive function in younger adults.

Microgravity has been shown to be a significant stressor on the cardiovascular system and the brain due to the redistribution of fluids that occurs in the absence of gravitational force, but there is scarce literature surrounding the effects of microgravity on cerebral hemodynamics and cognition. Understanding the early effects that simulated gravity has on cognitive function is essential for developing proper physical and cognitive countermeasures to assure safe and effective cognitive/decisions making while astronauts prepare for the initial launch or when they arrive in a microgravity environment. Therefore, this study aims to determine how an acute simulation of microgravity would alter cerebral oxygenation and executive functions. Sixty-five young healthy participants (22 ± 6 years, 21 females) completed a thirty (30) minute horizontal (00 tilt) followed by a 90-min - 6° head-down-tilt (HDT) protocol. Cerebral oxygenation in the prefrontal cortex was monitored throughout the testing session using near-infrared spectroscopy. Cognition was also measured using a computerized Stroop Task. Our results demonstrate that cerebral oxygenation was higher during HDT compared to the horizontal supine position (9.11 ± 1.3 vs. 7.51 ± 1.8, p = 0.02). For the cognitive results, the non-executive performance of the Stroop task remained stable during HDT (652.46 ± 19.3 vs. 632.49 ± 14.5, p = 0.09). However, reaction time during the executive task performance was improved after the HDT (1058 ± 195-950 ± 158 ms, p < 0.01). Our results suggest that an acute bout of simulated microgravity can enhance executive functioning.

Sensitivity to Experiencing Alcohol Hangovers: Reconsideration of the 0.11% Blood Alcohol Concentration (BAC) Threshold for Having a Hangover.

The 2010 Alcohol Hangover Research Group consensus paper defined a cutoff blood alcohol concentration (BAC) of 0.11% as a toxicological threshold indicating that sufficient alcohol had been consumed to develop a hangover. The cutoff was based on previous research and applied mostly in studies comprising student samples. Previously, we showed that sensitivity to hangovers depends on (estimated) BAC during acute intoxication, with a greater percentage of drinkers reporting hangovers at higher BAC levels. However, a substantial number of participants also reported hangovers at comparatively lower BAC levels. This calls the suitability of the 0.11% threshold into question. Recent research has shown that subjective intoxication, i.e., the level of severity of reported drunkenness, and not BAC, is the most important determinant of hangover severity. Non-student samples often have a much lower alcohol intake compared to student samples, and overall BACs often remain below 0.11%. Despite these lower BACs, many non-student participants report having a hangover, especially when their subjective intoxication levels are high. This may be the case when alcohol consumption on the drinking occasion that results in a hangover significantly exceeds their "normal" drinking level, irrespective of whether they meet the 0.11% threshold in any of these conditions. Whereas consumers may have relative tolerance to the adverse effects at their "regular" drinking level, considerably higher alcohol intake-irrespective of the absolute amount-may consequentially result in a next-day hangover. Taken together, these findings suggest that the 0.11% threshold value as a criterion for having a hangover should be abandoned.

Physical activity of children and youth in Nova Scotia from 2001/02 and 2005/06.

OBJECTIVES: This paper reports on physical activity of students in grades 3, 7, and 11 from two surveillance studies (from 2001 and 2005). METHODS: Randomly selected students (Study1 n=1730; Study2 n=2341) from randomly selected schools in Nova Scotia participated. Physical activity was measured for seven consecutive days using Actigraph accelerometers. Descriptive statistics were calculated for moderate, hard, and very hard intensity, and total minutes of physical activity. Between study, grade, and sex differences were determined using univariate Analyses of Variance. RESULTS: Students in Study2 were significantly less active (mean [SD]=531.0 [392.3] min/week) than Study1 (662.2 [495.1] min/week). Girls were significantly less active (525.4 [419.1] min/week) than boys (657.1 [460.3] min/week). Students in grade 11 were significantly less active (225.2 [171.1] min/week) than students in grade 7 (457.5 [227.2] min/week) who were significantly less active than students in grade 3 (1038.4 [387.6] min/week). A significant study-grade interaction indicated that compared to students in grades 7 and 11, the level of physical activity in students in grade 3 was considerably lower in Study2 compared to Study1. CONCLUSIONS: Given the lower level of physical activity found in Study2, efforts at informing public policy and strategies that promote physical activity in children and youth should be made.

Transition to practice in radiation oncology: Mind the gap.

INTRODUCTION: Physicians entering independent practice often express apprehension in managing the non-clinical aspects of practice. This study examined the perceived preparedness of radiation oncology (RO) residents for independent practice, identified education gaps, and discussed how these deficiencies could be addressed. MATERIALS AND METHODS: Focus groups with senior RO residents, fellows, new-to-practice radiation oncologists (ROs), and residency program directors were conducted. Data were coded using the Canadian Medical Education Directives for Specialists (CanMEDS) competencies using thematic analysis. RESULTS: Commonly reported gaps in the transition to practice (TtP) for ROs were lack of experience with: practice management, understanding the structure and function of the health care system and how it varies by jurisdiction, financial planning, effective communication and collaboration with other health care team members, creation of accurate and timely documentation, and radiotherapy problem-solving related to treatment planning and evaluation. Suggestions to address these challenges included use of mentorship, educational resources, courses, simulation-based medical education, improved graded responsibility, resident longitudinal clinics, and formal curricula in radiation therapy planning and evaluation. CONCLUSION: There are gaps in TtP education for RO trainees with opportunities for enrichment through the forthcoming implementation of a competency-based medical education framework in 2019. The gap in perceived competency in physician-related radiotherapy tasks may be caused by the complex interaction of clinical workflow processes, people and technology that has led to ineffective integration of trainees. The data are informative to medical education leaders for the development of comprehensive TtP curricula.

Overweight Nova Scotia children and youth: the roles of household income and adherence to Canada's Food Guide to Healthy Eating.

OBJECTIVE: Poor diet quality has been observed in Nova Scotia children and youth, characterized by low intake from the traditional four food groups and a high intake from the Other Foods category. In this study, we addressed how household income and adherence to Canada's Food Guide to Healthy Eating influenced weight status category in Nova Scotia children and youth. METHODS: During the 2005-06 school year, data were collected from 2,296 students and their parents, across Nova Scotia. Questionnaires and anthropometric measurements were obtained from grades 3, 7 and 11 students. The grade 3 students were excluded from the dietary intake assessment. The information collected from the online 24-hour food recalls and food frequency questionnaires were analyzed for adherence to Canada's Food Guide to Healthy Eating recommendations. A general linear model was employed to examine the relationships between household income, food group and weight status category. RESULTS: Overall adherence to Canada's Food Guide to Healthy Eating was low among grades 7 and 11 students. Fewer servings from Grain Products, Milk Products and Vegetables and Fruit were observed in at risk of overweight and overweight students. At risk of overweight and overweight were significantly related to lower household income in grades 3 and 11. Our results show that the rates of overweight in Nova Scotia students are double those reported by the 2004 Canadian Community Health Survey. CONCLUSION: Household income and dietary intake play significant roles in weight status among Nova Scotia children and youth.

Physical and psychomotor functioning of females the morning after consuming low to moderate quantities of beer.

OBJECTIVE: Individuals in society typically consume alcohol in "standard" units (e.g., bottles/cans of beer, glasses of wine, shots of distilled spirits) over a reasonable period of time whereas in many hangover studies, participants consume a single large dose of alcohol relative to their body weight in a short period of time. The purpose of this study was to examine how consuming low to moderate "standard" quantities of alcohol over an evening affected subjective hangover ratings, physical, physiological, and psychomotor functioning of adult females the next morning. METHOD: Twelve females consumed zero, two, four, or six bottles of beer (341 ml; 5% weight by volume) in a within-subjects design. Blood alcohol concentration, resting heart rate, resting blood pressure, and grip strength were measured prior to consumption, 1 hour after consumption, and the following morning (9 hours after consumption). In the morning, participants rated the presence of eight hangover symptoms, completed a four-choice reaction time test, and performed tests of submaximal and maximal endurance on a treadmill; blood lactate, blood glucose, and perceived exertion were recorded during submaximal and maximal exercise. RESULTS: Heart rate, blood pressure, grip strength, blood lactate, blood glucose, and reaction time did not significantly change the next morning as a function of alcohol dose. Participants made more choice reaction errors after consuming six than zero bottles of beer. CONCLUSION: These results suggest that consuming moderate quantities of beer affects decision making but not physical and physiological performance in adult females the next morning.

Physical activity and body mass index in grade 3, 7, and 11 Nova Scotia students.

PURPOSE: This study examined the average time spent in moderate or more intense physical activities according to weight status in randomly selected Nova Scotia students. METHODS: A total of 1653 students participated in this study: 575 in grade 3, 558 in grade 7, and 520 in grade 11. Physical activity was measured for seven consecutive days using MTI accelerometers. Activity counts were classified according to moderate (3-5.9 METs), hard (6-8.9 METs), and very hard (>9 METs) intensities. Height and weight were measured and body mass index (BMI) calculated. Centers for Disease Control and Prevention BMI criteria for age and sex were used to classify the students as normal weight (< or =85th percentile), at risk of overweight (>85th and < or =95th percentiles), and overweight (>95th percentile). ANOVA was used to compare the average time spent in moderate, hard, and very hard physical activities according to BMI status in boys and girls in grades 3, 7, and 11. RESULTS: Although age and sex differences existed, there were no significant differences in the average time spent in moderate or more intense physical activities in the BMI groups. CONCLUSION: Further research is warranted to elucidate the factors surrounding the relationship between physical activity and BMI in children and youths.

The alcohol hangover research group consensus statement on best practice in alcohol hangover research.

Alcohol-induced hangover, defined by a series of symptoms, is the most commonly reported consequence of excessive alcohol consumption. Alcohol hangovers contribute to workplace absenteeism, impaired job performance, reduced productivity, poor academic achievement, and may compromise potentially dangerous daily activities such as driving a car or operating heavy machinery. These socioeconomic consequences and health risks of alcohol hangover are much higher when compared to various common diseases and other health risk factors. Nevertheless, unlike alcohol intoxication the hangover has received very little scientific attention and studies have often yielded inconclusive results. Systematic research is important to increase our knowledge on alcohol hangover and its consequences. This consensus paper of the Alcohol Hangover Research Group discusses methodological issues that should be taken into account when performing future alcohol hangover research. Future research should aim to (1) further determine the pathology of alcohol hangover, (2) examine the role of genetics, (3) determine the economic costs of alcohol hangover, (4) examine sex and age differences, (5) develop common research tools and methodologies to study hangover effects, (6) focus on factor that aggravate hangover severity (e.g., congeners), and (7) develop effective hangover remedies.

Are overweight students in Grades 3, 7, and 11 less physically active than their healthy weight counterparts?

OBJECTIVE: This study compared the accumulated minutes of objectively measured physical activity in 1,790 boys and girls in Grades 3, 7, and 11 classified as healthy weight, at risk of overweight, and overweight. METHODS: Height and weight were measured and body mass index calculated. Minutes of sedentary, light, moderate, hard, and very hard physical activity were obtained from a seven-day measurement of physical activity using an accelerometer (Actigraph, mode 7164; MTI). RESULTS: In Grade 3, boys (p=0.000) and girls (p=0.012) classified as overweight obtained significantly fewer minutes of very hard physical activity compared with their healthy weight counterparts. Boys in Grade 7 considered overweight obtained significantly fewer minutes of hard (p=0.002) and very hard physical activity (p=0.006) compared with boys who were a healthy weight. There were no significant differences in minutes of sedentary, light, moderate, hard, or very hard intensity physical activity in the boys and girls in Grade 11, who were considered a healthy weight, at risk of overweight, or overweight. CONCLUSIONS: Weak and inconsistent support was provided for the notion that boys and girls classified overweight are less physically active than their healthy weight counterparts.

Vitamin C supplementation and salivary immune function following exercise-heat stress.

PURPOSE: Prolonged physical exertion and environmental heat stress may elicit postexercise depression of immune cell function, increasing upper respiratory tract infection (URTI) susceptibility. We investigated the effects of acute and short-term vitamin C (VC) compared with placebo (PL) supplementation on URTI susceptibility, salivary immunoglobulin A (s-IgA), and cortisol responses in healthy individuals following prolonged exercise-heat stress. METHODS: Twelve participants were randomized into the VC or PL group in a double-blind design. For 12 days, participants consumed 3x500 mg tablets of VC or PL per day, with testing completed at baseline, then following acute (1 d) and short-term (8 d) supplementation. Participants performed 120.1+/-49.6 min of cycling at 54+/-6% VO2max in a hot (34.8+/-1.0 degrees C and 13+/-3% relative humidity) environment, with saliva samples collected at pre-, post-, and 72 h postexercise. Health logs specifying URTI symptoms were completed for 7 days postexercise. RESULTS: A 2x3x3 mixed ANOVA with a post hoc Bonferroni correction factor revealed a significant linear trend in postexercise cortisol attenuation in the VC group, 21.7+/-15.1 nmol/L (mean+/-SD) at baseline, to 13.5+/-10.0 at acute, to 7.6+/-4.2 after short term (P=.032). No differences were detected in ratio of s-IgA to protein or URTI symptoms between groups. CONCLUSIONS: These data suggest that vitamin C supplementation can decrease postexercise cortisol in individuals performing exercise similar to that of a half-marathon or marathon in hot conditions. However, no changes in s-IgA and URTI were evident, possibly due to previous moderate training and reduced physical and psychological stress compared with athletes participating in ultramarathons.

Type 2 diabetes mellitus, resistance training, and innate immunity: is there a common link?

Type 2 diabetes mellitus is a serious chronic disease that is very prevalent in the developed world. The etiology of this disease is not well understood. Recently, the role of the innate immune system in the pathogenesis of type 2 diabetes and its complications has received a great deal of attention. Cytokines, acute phase proteins, and phagocytes have been implicated in this model. Resistance training has known benefits in type 2 diabetic patients and older adults, such as improved insulin action, insulin sensitivity, fasting blood glucose and insulin, and glucose tolerance levels. Actions of pro-inflammatory mediators linked to dysregulated innate immune activity have been associated with type 2 diabetes. The immunomodulatory effects of exercise, and in particular approaches such as resistance training, may provide a strategy to counter these pro-inflammatory effectors. However, the effects of resistance training on innate immunity have not been studied extensively in adults with type 2 diabetes or in older adults who are at increased risk for development of type 2 diabetes. This review discusses the possibility that resistance training may have positive effects on innate immunity in this population and so may provide benefits in addition to improving strength and functional abilities. In particular, the potential of resistance training to modulate pro-inflammatory parameters associated with type 2 diabetes, as a strategy that could provide multiple beneficial health outcomes, is addressed.

Early effects of spinal cord transection on skeletal muscle properties.

Modulation of beta-adrenergic receptor (beta-AR) activity affects muscle mass and could have a role in the reduction of muscle mass observed following spinal cord transection (Tx). The aims of this study were to examine the early acute effects of Tx on muscle mass, total and myofibrillar protein concentrations, cytochrome c oxidase activity, and beta-AR density of skeletal muscle, to ascertain if any change in muscle properties could be related to beta-AR signalling events. Female Sprague-Dawley rats (n = 33; approximately 255 g) were randomly assigned to 4 experimental groups: control 4 d, control 8 d, Tx 4 d, and Tx 8 d. A complete Tx was performed surgically at the T10 cord level. Compared with controls, muscle mass and muscle - body mass ratios decreased significantly following Tx, with no significant change observed in total and myofibrillar protein concentrations. Spinal cord Tx also resulted in a significant decrease in plantaris cytochrome c oxidase activity by 24% at Tx 4 d and 28% at Tx 8 d (p < 0.05). Beta-AR density of the lateral gastrocnemius was unchanged; however, the beta-AR density of the forelimb triceps brachii m. was found to increase after Tx. Our results suggest that changes in muscle mass and cytochrome c oxidase activity rapidly occur after Tx and do not appear to be related to changes in beta-AR density.

Natural killer cells and exercise training in the elderly: a review.

Consistent reports of the positive relationship between regular physical activity and immunosenescence have generated much excitement in the field of exercise immunology. It is generally accepted that natural killer (NK) cell activity per NK cell decreases with age; decreases in NKCA have been associated with infection and death in the aged. The effects of exercise and training on natural killer cells, components of the innate immune system, have been studied extensively in young people. However, the published research on the elderly population is limited. Generally it has been found that training increases or does not change natural killer cell activity or counts in the elderly. The clinical relevance of these results is yet to be fully explored. In addition, the limitations of these studies on immune function have been many, and studies are often difficult to compare due to differences in their methods and presentation of results.