1.
Identification of a macro-alkaline phosphatase complex in a patient with inflammatory bowel disease.
Ann Clin Biochem
; 49(Pt 4): 405-7, 2012 Jul.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22454544
RESUMO
We report the rare finding of a macro-alkaline phosphatase (macroALP) complex in a patient with a previously unexplained raised alkaline phosphatase activity. The clinical symptoms were persistent, daily diarrhoea for two months with blood in the stool. The patient was subsequently diagnosed with inflammatory bowel disease, specifically ulcerative colitis, following a rectal biopsy and colonoscopy. Two cases of macroALP associated with ulcerative colitis have been reported before, suggesting there could be an increased prevalence of macroALP in these patients.
Assuntos
Fosfatase Alcalina/metabolismo , Doenças Inflamatórias Intestinais/enzimologia , Adulto , Humanos , Masculino
2.
BMJ
; 349: g6293, 2014 Oct 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25336445