Detalhe da pesquisa
1.
Targeted isolation of diverse human protective broadly neutralizing antibodies against SARS-like viruses.
Nat Immunol
; 23(6): 960-970, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35654851
2.
Broadly neutralizing anti-S2 antibodies protect against all three human betacoronaviruses that cause deadly disease.
Immunity
; 56(3): 669-686.e7, 2023 03 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-36889306
3.
Validating Enterovirus D68-2Apro as an Antiviral Drug Target and the Discovery of Telaprevir as a Potent D68-2Apro Inhibitor.
J Virol
; 93(7)2019 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30674624
4.
Development of broad-spectrum enterovirus antivirals based on quinoline scaffold.
Bioorg Chem
; 101: 103981, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32559580
5.
The L46P mutant confers a novel allosteric mechanism of resistance toward the influenza A virus M2 S31N proton channel blockers.
Mol Pharmacol
; 96(2): 148-157, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31175183
6.
Chemical Genomics Approach Leads to the Identification of Hesperadin, an Aurora B Kinase Inhibitor, as a Broad-Spectrum Influenza Antiviral.
Int J Mol Sci
; 18(9)2017 Sep 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28885544
7.
Effects of transportation stress and addition of salt to transport water on the skin mucosal homeostasis of rainbow trout (Oncorhynchus mykiss).
Aquaculture
; 435: 120-127, 2015 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25705060
8.
Deep repertoire mining uncovers ultra-broad coronavirus neutralizing antibodies targeting multiple spike epitopes.
bioRxiv
; 2023 Mar 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-37034676
9.
Broadly neutralizing antibodies targeting a conserved silent face of spike RBD resist extreme SARS-CoV-2 antigenic drift.
bioRxiv
; 2023 Apr 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-37162858
10.
Broadly neutralizing antibodies to SARS-related viruses can be readily induced in rhesus macaques.
Sci Transl Med
; 14(657): eabl9605, 2022 08 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35947674
11.
Targeted isolation of panels of diverse human protective broadly neutralizing antibodies against SARS-like viruses.
bioRxiv
; 2022 Feb 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35169804
12.
Broadly neutralizing anti-S2 antibodies protect against all three human betacoronaviruses that cause severe disease.
bioRxiv
; 2022 Mar 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35291291
13.
Discovery of Potent and Broad-Spectrum Pyrazolopyridine-Containing Antivirals against Enteroviruses D68, A71, and Coxsackievirus B3 by Targeting the Viral 2C Protein.
J Med Chem
; 64(12): 8755-8774, 2021 06 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-34085827
14.
Enterovirus D68 Antivirals: Past, Present, and Future.
ACS Infect Dis
; 6(7): 1572-1586, 2020 07 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32352280
15.
Discovery of M2 channel blockers targeting the drug-resistant double mutants M2-S31N/L26I and M2-S31N/V27A from the influenza A viruses.
Eur J Pharm Sci
; 141: 105124, 2020 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31669761
16.
Investigation of the Drug Resistance Mechanism of M2-S31N Channel Blockers through Biomolecular Simulations and Viral Passage Experiments.
ACS Pharmacol Transl Sci
; 3(4): 666-675, 2020 Aug 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-32832869
17.
A Novel Capsid Binding Inhibitor Displays Potent Antiviral Activity against Enterovirus D68.
ACS Infect Dis
; 5(11): 1952-1962, 2019 11 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31532189
18.
Focusing on the Influenza Virus Polymerase Complex: Recent Progress in Drug Discovery and Assay Development.
Curr Med Chem
; 26(13): 2243-2263, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-29984646
19.
Discovery of Quinoline Analogues as Potent Antivirals against Enterovirus D68 (EV-D68).
J Med Chem
; 62(8): 4074-4090, 2019 04 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-30912944
20.
Identification of NMS-873, an allosteric and specific p97 inhibitor, as a broad antiviral against both influenza A and B viruses.
Eur J Pharm Sci
; 133: 86-94, 2019 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30930289