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Am J Transplant ; 16(5): 1604-11, 2016 05.
Artigo em Inglês | MEDLINE | ID: mdl-26700736

RESUMO

Delayed graft function (DGF) is a common and costly complication of kidney transplantation. In July 2011, we established a multidisciplinary DGF clinic managed by nurse practitioners to facilitate early discharge and intensive management of DGF in the outpatient setting. We compared length of stay, 30-day readmission, acute rejection, and patient/graft survival in 697 consecutive deceased donor kidney transplantations performed between July 2009 and July 2014. Patients were divided into three groups: no DGF (n = 487), DGF before implementation of the DGF clinic (n = 118), and DGF clinic (n = 92). Baseline characteristics including age, gender, panel reactive antibody, retransplantation rates, HLA mismatches, induction, and maintenance immunosuppression were not significantly different between pre- and post-DGF clinic groups. Length of stay was significantly longer in pre-DGF clinic (10.9 ± 6.2 vs. 6.1 ± 2.1 days, p < 0.001). Thirty-day readmission (21% vs. 16%), graft loss (7% vs. 20%), and patient death (2% vs. 11%) did not differ significantly between pre- and post-DGF clinic. Patients in the DGF clinic were less likely to develop acute rejection (21% vs. 40%, p = 0.006). Outpatient management of DGF in a specialized clinic is associated with substantially shorter hospitalization and lower incidence of acute rejection without significant difference in 30-day readmission or patient and graft survival.


Assuntos
Função Retardada do Enxerto/terapia , Rejeição de Enxerto/prevenção & controle , Falência Renal Crônica/cirurgia , Tempo de Internação/estatística & dados numéricos , Gerenciamento Clínico , Feminino , Seguimentos , Taxa de Filtração Glomerular , Rejeição de Enxerto/epidemiologia , Sobrevivência de Enxerto , Humanos , Incidência , Testes de Função Renal , Transplante de Rim , Masculino , Pessoa de Meia-Idade , Pacientes Ambulatoriais , Prognóstico , Reoperação/estatística & dados numéricos , Estudos Retrospectivos , Fatores de Risco , Wisconsin/epidemiologia
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