Detalhe da pesquisa
1.
General Design Strategy to Precisely Control the Emission of Fluorophores via a Twisted Intramolecular Charge Transfer (TICT) Process.
J Am Chem Soc
; 144(43): 19778-19790, 2022 11 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36191139
2.
Application of Acoustic Ejection MS System to High-Throughput Screening for SARS-CoV-2 3CL Protease Inhibitors.
Chem Pharm Bull (Tokyo)
; 70(3): 199-201, 2022 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34937844
3.
Structure, solubility, and permeability relationships in a diverse middle molecule library.
Bioorg Med Chem Lett
; 37: 127847, 2021 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33571648
4.
Metabolic-Pathway-Oriented Screening Targeting S-Adenosyl-l-methionine Reveals the Epigenetic Remodeling Activities of Naturally Occurring Catechols.
J Am Chem Soc
; 142(1): 21-26, 2020 01 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31869215
5.
A cytosolically localized far-red to near-infrared rhodamine-based fluorescent probe for calcium ions.
Analyst
; 145(23): 7736-7740, 2020 Nov 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-33000768
6.
A Fluorescent Probe for Rapid, High-Contrast Visualization of Folate-Receptor-Expressing Tumors Inâ Vivo.
Angew Chem Int Ed Engl
; 59(15): 6015-6020, 2020 04 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31984590
7.
Design and Synthesis of an Activatable Photoacoustic Probe for Hypochlorous Acid.
Anal Chem
; 91(14): 9086-9092, 2019 07 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-31265237
8.
A small-molecule AdipoR agonist for type 2 diabetes and short life in obesity.
Nature
; 503(7477): 493-9, 2013 Nov 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-24172895
9.
Development of a Novel Intraocular-Pressure-Lowering Therapy Targeting ATX.
Biol Pharm Bull
; 42(11): 1926-1935, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31685776
10.
Development of a Series of Practical Fluorescent Chemical Tools To Measure pH Values in Living Samples.
J Am Chem Soc
; 140(18): 5925-5933, 2018 05 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29688713
11.
Development of an Azo-Based Photosensitizer Activated under Mild Hypoxia for Photodynamic Therapy.
J Am Chem Soc
; 139(39): 13713-13719, 2017 10 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28872304
12.
Discovery of Cell-Type-Specific and Disease-Related Enzymatic Activity Changes via Global Evaluation of Peptide Metabolism.
J Am Chem Soc
; 139(9): 3465-3472, 2017 03 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28191944
13.
Structural development of 1,2,3,4-tetrahydroisoquinoline-type positive allosteric modulators of prostacyclin receptor (IPPAMs) to improve metabolic stability, and investigation of metabolic fate.
Bioorg Med Chem Lett
; 27(15): 3572-3575, 2017 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28587821
14.
Synthesis of both enantiomers of 1,2,3,4-tetrahydroisoquinoline derivative IPPAM-1 and enantio-dependency of its positive allosteric modulation of prostacyclin receptor.
Bioorg Med Chem Lett
; 27(11): 2567-2570, 2017 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28462839
15.
Discovery of benzo[g]indoles as a novel class of non-covalent Keap1-Nrf2 protein-protein interaction inhibitor.
Bioorg Med Chem Lett
; 27(22): 5006-5009, 2017 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29037947
16.
An Activatable Photosensitizer Targeted to γ-Glutamyltranspeptidase.
Angew Chem Int Ed Engl
; 56(35): 10418-10422, 2017 08 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-28639393
17.
Development of Chemical Tools to Monitor and Control Isoaspartyl Peptide Methyltransferase Activity.
Angew Chem Int Ed Engl
; 56(1): 153-157, 2017 01 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27933714
18.
A novel diacylglycerol kinase α-selective inhibitor, CU-3, induces cancer cell apoptosis and enhances immune response.
J Lipid Res
; 57(3): 368-79, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26768655
19.
Protein-Coupled Fluorescent Probe To Visualize Potassium Ion Transition on Cellular Membranes.
Anal Chem
; 88(5): 2693-700, 2016 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26894407
20.
Unexpected Photo-instability of 2,6-Sulfonamide-Substituted BODIPYs and Its Application to Caged GABA.
Chembiochem
; 17(13): 1233-40, 2016 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27038199