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1.
Neuropathology ; 36(6): 579-583, 2016 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-27910213

RESUMO

A 46-year-old woman presented with headache and right hemiparesis. MRI demonstrated a mass in the left middle fossa. Total resection was performed. A histological examination of the tumor specimen showed several characteristic morphological features. A chordoid meningioma showing an epithelial-like palisade arrangement was observed. An anaplastic short spindle cell tumor exhibiting a fascicular pattern was considered to be a rhabdomyosarcoma. After conventional radiotherapy, the tumor was well controlled without any neurological deficit for 20 months. When subsequent recurrences were observed, the patient was treated by surgery, stereotactic radiosurgery and chemotherapy. Thirty-two months after the initial treatment, the patient died due to intracranial dissemination and an autopsy was performed. The histological examination of the recurrent and autopsy specimens showed a prominent sarcoma component. This case appears to be the first reported intracranial tumor diagnosed as a dedifferentiated chordoid meningioma with rhabdomyosarcomatous differentiation.


Assuntos
Desdiferenciação Celular , Fossa Craniana Média/diagnóstico por imagem , Neoplasias Meníngeas/diagnóstico por imagem , Meningioma/diagnóstico por imagem , Neoplasias da Base do Crânio/diagnóstico por imagem , Encéfalo/diagnóstico por imagem , Encéfalo/patologia , Fossa Craniana Média/patologia , Feminino , Humanos , Neoplasias Meníngeas/patologia , Meningioma/patologia , Pessoa de Meia-Idade , Neoplasias da Base do Crânio/patologia
2.
J Neuroendovasc Ther ; 17(8): 153-158, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37609574

RESUMO

Objective: Selective transvenous embolization (sTVE) is an effective technique for treating dural arteriovenous fistulas (DAVFs); however, selective catheterization into the shunted pouch is often difficult due to the acute angle of the access route between the target pouch and dural sinus. We present our initial experience using a steerable microcatheter (SM) to manually control the tip angle for selective catheterization and sTVE of DAVFs. Methods: Thirteen consecutive cases of DAVFs and 16 procedures that involved sTVE using SM between October 2016 and October 2018 were reviewed. SMs were used for selective catheterization of shunted venous pouches and/or the affected sinus and coil embolization. We evaluated the maneuverability of the SM, the success of selective catheterization into the target lesions, and the results of endovascular treatments. Results: Endovascular procedures were performed in a single session in 10 cases and in two staged sessions in 3 cases. There was no difficulty in maneuverability of the SM. Successful selective catheterization was achieved in 26 of 27 target lesions. Immediately after embolization, angiography showed complete occlusion in 10 cases and marked reduction in 3 cases. During 40.9 months of mean follow-up, 12 cases showed complete occlusion and one case showed a small residual shunt on MRI. Procedure-related complications of spontaneous thrombosis of the affected sinus were observed in one case. There were no cases of recurrence or exacerbation during follow-up. Conclusion: SM is useful for selective catheterization for target lesions during sTVE of DAVFs.

3.
No Shinkei Geka ; 40(11): 967-71, 2012 Nov.
Artigo em Japonês | MEDLINE | ID: mdl-23100384

RESUMO

OBJECT: Chronic subdural hematoma is often seen in elderly patients. One burr hole surgery with subdural drainage has been performed and prognosis is good, but the recurrence rate is still about 10%. To prevent the recurrence, we used Kampo-medicine Gorei-san with tranexamic acid after surgery. The purpose of this study is to investigate if the recurrence is able to prevent by using these drugs. METHODS: From January 2008 to December 2010, 199 consecutive cases with chronic subdural hematoma were examined at Nagatomi Neurosurgical Hospital. Patients were divided into four groups according to the administered drugs; Gorei-san, tranexamic acid, Gorei-san with tranexamic acid and no drug groups. The recurrence rate was compared between each group. The chi-square test was performed as a statistical analysis. RESULTS: In all patients, the mean age was 77.7±10.5 years. There were 140 males and 59 females. Overall recurrence rate was 7.0%. Each recurrence rate was 8.3% in the Gorei-san administration group, and 10.9% in the tranexamic acid group, and 2.9% in Gorei-san with tranexamic acid group, and 5.7% in the no-drug group. There was no significant difference between the four groups in statistical analysis. CONCLUSIONS: Gorei-san with the tranexamic acid administration group had the minimum recurrence. There was no significant difference but these drugs would be preventable recurrence of chronic subdural hematoma. We need to accumulate more cases as a prospective study in the future.


Assuntos
Medicamentos de Ervas Chinesas/uso terapêutico , Hematoma Subdural Crônico/tratamento farmacológico , Prevenção Secundária , Ácido Tranexâmico/uso terapêutico , Idoso , Idoso de 80 Anos ou mais , Quimioterapia Combinada , Feminino , Hematoma Subdural Crônico/cirurgia , Humanos , Masculino , Medicina Kampo , Pessoa de Meia-Idade , Resultado do Tratamento
4.
Interv Neuroradiol ; 26(3): 254-259, 2020 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-31856646

RESUMO

Diploic arteriovenous fistulas are rare arteriovenous shunts involving the skull, which often drain antegradely into the internal or external jugular veins. Diploic arteriovenous fistulas with marked cortical venous reflux are extremely rare. Here, we present the case of a patient with diploic arteriovenous fistulas with marked cortical venous reflux and a literature review. A 73-year-old woman presented with headache. Magnetic resonance angiography revealed abnormal signal intensity in the diploic layer of the left frontal bone. Digital subtraction angiography demonstrated a diploic arteriovenous fistulas located in the left frontal bone. The arteriovenous fistulas were fed by multiple branches of the left external carotid artery, mainly from the middle meningeal artery, branches of the ophthalmic artery, and the inferolateral trunk. The fistulas drained into the cerebral cortical veins surrounding the frontal lobe via an emissary vein of the frontal bone. With the femoral arterial approach, transarterial catheterization into the shunted diploic vein was performed with a small tapered microcatheter, and the arteriovenous fistulas were completely embolized with N-butyl-2-cyanoacrylate. The patient was discharged without complications. No recurrent arteriovenous fistulas were observed during the 12-month follow-up period. Endovascular treatment is an effective technique for the curative treatment of diploic arteriovenous fistulas.


Assuntos
Fístula Arteriovenosa/diagnóstico por imagem , Fístula Arteriovenosa/terapia , Embolização Terapêutica/métodos , Malformações Arteriovenosas Intracranianas/diagnóstico por imagem , Malformações Arteriovenosas Intracranianas/terapia , Idoso , Angiografia Digital , Angiografia Cerebral , Diagnóstico Diferencial , Embucrilato , Feminino , Humanos , Angiografia por Ressonância Magnética
5.
Neuroradiology ; 51(3): 175-81, 2009 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-19104792

RESUMO

INTRODUCTION: This study aimed to define the patterns of basal cerebral venous drainage (BCVD) from cavernous sinus dural arteriovenous fistulas (CSDAVFs). MATERIALS AND METHODS: Forty sets of selective angiographic data from 36 patients with spontaneous CSDAVFs (age range, 53-79 years) were retrospectively analyzed for their drainage patterns. Three types of BCVD were observed, i.e., superolateral type, BCVD via the deep middle cerebral vein or uncal vein; posterolateral type, BCVD via the superior petrosal sinus and petrosal vein; and posteromedial type, BCVD via the bridging vein and the anterior pontomesencephalic vein. MR images and/or 3D-DSA images were also reviewed when available. RESULTS: BCVD from CSDAVF was found in 12 patients (30%), and the other drainage routes included the superior ophthalmic vein in 25 (63%), the inferior petrosal sinus in 17 (43%), the superficial middle cerebral vein in 17 (43%), intercavernous sinus in 15 (38%), the superior petrosal sinus in seven (18%), and pterygoid plexus in two (5%), respectively. In 12 patients with BCVD, superolateral type was found in four (33%), posterolateral type in five (42%), and posteromedial type in seven (58%). Four cases of posteromedial type were associated with other types of BCVD. CONCLUSION: CSDAVFs are often associated with BCVD via three different pathways. The posteromedial type via the bridging vein is the most frequent type of BCVD.


Assuntos
Velocidade do Fluxo Sanguíneo , Seio Cavernoso/patologia , Seio Cavernoso/fisiopatologia , Malformações Vasculares do Sistema Nervoso Central/patologia , Malformações Vasculares do Sistema Nervoso Central/fisiopatologia , Circulação Cerebrovascular , Idoso , Feminino , Humanos , Angiografia por Ressonância Magnética , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos
6.
Neuroradiology ; 50(12): 1013-23, 2008 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-18636248

RESUMO

INTRODUCTION: We evaluated the normal venous anatomy of the anterior medullary/anterior pontomesencephalic venous (AMV/APMV) system and bridging veins connected to the dural sinuses using magnetic resonance (MR) imaging and demonstrated cases of dural arteriovenous fistulas (DAVFs) with bridging venous drainage. MATERIALS AND METHODS: MR images obtained using a 3D gradient echo sequence in 70 patients without lesions affecting the deep or posterior venous channels were reviewed to evaluate the normal anatomy of the AMV/APMV system and bridging veins. MR images and digital subtraction angiography in 80 cases with intracranial or craniocervical junction DAVFs were reviewed to evaluate the bridging venous drainage from DAVFs. RESULTS: MR images clearly revealed AMV/APMV in 35 cases. Fifteen cases showed a direct connection between AMV and APMV, while 15 cases showed an indirect communication via the transverse pontine vein or the bridging vein. In the five remaining cases, the AMV and APMV end separately to the bridging vein or the transverse pontine vein. Bridging veins were identified in 34 cases, connecting to the cavernous sinus in 33, to the suboccipital cavernous sinus in 11, and the inferior petrosal sinus in five cases. In 80 DAVF cases, seven of 40 cavernous sinus DAVFs, two craniocervical junction DAVFs, and one inferior petrosal sinus DAVF drained via bridging veins to the brain stem. CONCLUSION: The AMV/APMV and bridging veins showed various anatomies and frequently showed a connection to the cavernous sinus. Knowledge of the venous anatomy is helpful for the diagnosis and intravascular treatment of DAVFs.


Assuntos
Tronco Encefálico/irrigação sanguínea , Malformações Vasculares do Sistema Nervoso Central/patologia , Malformações Vasculares do Sistema Nervoso Central/fisiopatologia , Circulação Cerebrovascular/fisiologia , Adulto , Idoso , Malformações Vasculares do Sistema Nervoso Central/diagnóstico por imagem , Veias Cerebrais/patologia , Veias Cerebrais/fisiopatologia , Estudos de Coortes , Cavidades Cranianas/patologia , Cavidades Cranianas/fisiopatologia , Imagem Ecoplanar , Feminino , Humanos , Imageamento Tridimensional , Masculino , Pessoa de Meia-Idade , Radiografia , Estudos Retrospectivos
7.
Surg Neurol ; 68(1): 99-102; discussion 102, 2007 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-17586239

RESUMO

BACKGROUND: We report on the case of a patient with meningioma that was correctly identified through biopsy. CASE DESCRIPTION: A 69-year-old woman presented with slight headache and was then examined at our hospital. Neurologic and physical examinations found no abnormality. Magnetic resonance imaging demonstrated a well-enhanced huge, dural-based, and plaque-like mass extending throughout the parietooccipital convexity and the posterior fossa. Tumors pressed the adjacent brain cortex while extending along the Virchow-Robin space. A CT scan also showed hyperostosis on the parietooccipital bone. Angiography demonstrated a vascular blush that appeared to be of a tumor-like shape. A biopsy was performed to confirm the diagnosis. The histologic findings demonstrated meningothelial meningioma with infiltration into the Virchow-Robin space. CONCLUSIONS: Many radiographic patterns of meningioma have been reported, but the present case is quite rare. The radiographic and pathologic findings in our patient are discussed.


Assuntos
Angiografia Cerebral , Imageamento por Ressonância Magnética , Neoplasias Meníngeas/diagnóstico , Meningioma/diagnóstico , Tomografia Computadorizada por Raios X , Biópsia , Artéria Carótida Interna/diagnóstico por imagem , Feminino , Humanos , Neoplasias Meníngeas/patologia , Meningioma/patologia , Pessoa de Meia-Idade , Invasividade Neoplásica
8.
J Neurosurg ; 105 Suppl: 133-8, 2006 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-18503346

RESUMO

OBJECT: Although there is no established treatment for primary central nervous system lymphoma (PCNSL), therapeutic protocols involving high-dose methotrexate therapy followed, in some cases, by whole-brain radiotherapy (WBRT) have generally been adopted, and they have yielded relatively favorable results. Gamma Knife surgery (GKS) is a stopgap measure to treat patients with PCNSL. The authors summarize the results of their cases and evaluate the efficacy and usefulness of GKS. METHODS: Between June 1999, and June 2005, 22 patients suffering from PCNSL were treated with GKS at the authors' institution and were followed up for more than 6 months. Some combination of chemotherapy and/or WBRT and/or microsurgery had been performed in 18 of the 22 patients before GKS. The remaining four patients had not undergone any previous treatment. In these patients, the mean tumor volume was 4.14 cm3, and the tumors were treated with a mean margin dose of 16.5 Gy to the 52.8% isodose line. Magnetic resonance imaging demonstrated the disappearance of the GKS-treated lesions; however, new lesions were observed in other regions of the brain in 10 patients and repeated GKS was performed in some cases. No local recurrences were observed an average of 19.4 months after GKS, and good level of quality of life (QOL) was maintained during this period. CONCLUSIONS: Gamma Knife surgery should be performed only for local tumor control as a stopgap measure in the treatment of PCNSL. It is noninvasive and safe, and its effects occur rapidly. Its use improves prognosis and enhances the patient's quality of life. Gamma Knife surgery should be considered one of the treatment strategies for patients with PCNSLs.


Assuntos
Neoplasias Encefálicas/patologia , Neoplasias Encefálicas/cirurgia , Linfoma/patologia , Linfoma/cirurgia , Cuidados Paliativos , Radiocirurgia , Adulto , Idoso , Idoso de 80 Anos ou mais , Estudos de Coortes , Intervalo Livre de Doença , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Carga Tumoral , Adulto Jovem
9.
J Clin Neurosci ; 13(9): 965-8, 2006 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-16904896

RESUMO

Pineal parenchymal tumour of intermediate differentiation (PPTID) in adults is rare and a treatment strategy for this condition has not yet been established. We present a case of an elderly patient treated with postoperative adjuvant therapy using radio- and chemotherapy. This 60-year-old man presented with a 3-month history of memory disturbance, gait instability and double vision. Computed tomography and magnetic resonance imaging demonstrated a mass in the pineal region that suggested a malignant tumour. Partial removal of the tumour was undertaken via the right occipital transtentorial approach. The histological diagnosis was PPTID. Postoperative radio- and chemotherapy were administered, with a good response. Little is known about the clinical behaviour of PPTID in adults. Our treatment plan indicates one effective option for the management of such tumours.


Assuntos
Tratamento Farmacológico/métodos , Glândula Pineal/efeitos dos fármacos , Glândula Pineal/efeitos da radiação , Pinealoma/tratamento farmacológico , Pinealoma/radioterapia , Radioterapia/métodos , Protocolos de Quimioterapia Combinada Antineoplásica/uso terapêutico , Carboplatina/uso terapêutico , Diplopia/etiologia , Diplopia/fisiopatologia , Tratamento Farmacológico/normas , Etoposídeo/uso terapêutico , Transtornos Neurológicos da Marcha/etiologia , Transtornos Neurológicos da Marcha/fisiopatologia , Humanos , Imageamento por Ressonância Magnética , Masculino , Transtornos da Memória/etiologia , Transtornos da Memória/fisiopatologia , Pessoa de Meia-Idade , Procedimentos Neurocirúrgicos , Glândula Pineal/cirurgia , Pinealoma/cirurgia , Doses de Radiação , Radioterapia/normas , Tomografia Computadorizada por Raios X , Resultado do Tratamento
10.
J Neurosurg ; 103(4): 656-61, 2005 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-16266048

RESUMO

OBJECT: The authors compared the usefulness of three-dimensional (3D) reconstructed computerized tomography (CT) angiography with 3D digital subtraction (DS) angiography in assessing intracranial aneurysms after clip placement. A retrospective review of clinical cases was performed. METHODS: Between May 2001 and May 2003, 17 patients with a total of 20 intracranial aneurysms underwent 3D CT and 3D DS angiography following clip placement. The authors assessed the presence or absence of residual aneurysm necks and stenoocclusive changes in the parent artery and the neighboring artery. The efficacy of CT angiographic visualization was also evaluated. In 12 of the 20 aneurysms, both 3D modalities similarly demonstrated the residual aneurysm neck and stenoocclusive changes in the parent artery and neighboring artery. Three-dimensional CT angiography failed to demonstrate three of the aneurysms, and the studies were not considered suitable for evaluation because of the presence of metallic artifacts. In the remaining five studies, the 3D CT angiograms did not effectively demonstrate the neighboring and parent arteries. The detectability of residual aneurysm necks was correlated with the clip material and with the number of clips applied. CONCLUSIONS: Three-dimensional DS angiography is still necessary in cases involving multiple clips or with cobalt alloy clips because the clips appear as metal artifacts on 3D CT angiography.


Assuntos
Angiografia Cerebral/métodos , Aneurisma Intracraniano/diagnóstico por imagem , Adulto , Idoso , Angiografia Digital , Artefatos , Angiografia Cerebral/normas , Feminino , Humanos , Imageamento Tridimensional , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Sensibilidade e Especificidade , Instrumentos Cirúrgicos , Tomografia Computadorizada por Raios X
11.
J Neurosurg ; 102 Suppl: 230-3, 2005 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-15662816

RESUMO

OBJECT: The authors performed a retrospective analysis of the radiation dose to the anterior visual pathway (AVP) to assess its tolerance to gamma knife surgery. METHODS: They examined five cases followed for more than 3 years. The AVP was treated with 10-Gy doses or higher. The mean maximum delivered dose to the AVP was 14 Gy. Ten gray or more was delivered to 25.5% of the ipsilateral AVP, 12 Gy or more to 12.5% of the ipsilateral AVP, and 14 Gy or more to 5.7% of the ipsilateral AVP. Although the mean follow-up period was 40.8 months (36-51 months), no cases of visual function deterioration developed. CONCLUSIONS: The tolerance dose of the AVP is considered to be less than 8 to 10 Gy; however, although the delivered dose to the AVP definitely exceeded the tolerance dose in all five cases, no visual disturbance has been identified. Longer follow up is required before any final conclusions may be drawn. Nonetheless, it is suggested that a visual disturbance may be avoided by using careful accurate dose planning even if the dose delivered to the AVP is higher than currently believed to be acceptable.


Assuntos
Adenoma/cirurgia , Hemangioma Cavernoso/cirurgia , Neoplasias Meníngeas/cirurgia , Meningioma/cirurgia , Neoplasias Hipofisárias/cirurgia , Tolerância a Radiação/efeitos da radiação , Radiocirurgia/instrumentação , Adenoma/patologia , Idoso , Feminino , Seguimentos , Hemangioma Cavernoso/patologia , Humanos , Imageamento por Ressonância Magnética , Masculino , Neoplasias Meníngeas/patologia , Meningioma/patologia , Pessoa de Meia-Idade , Neoplasias Hipofisárias/patologia , Doses de Radiação , Radiocirurgia/métodos , Carga Tumoral/efeitos da radiação , Vias Visuais/patologia
12.
AJNR Am J Neuroradiol ; 23(7): 1206-13, 2002 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-12169481

RESUMO

BACKGROUND AND PURPOSE: Complete occlusion of intracranial aneurysms is the goal of endovascular treatment and is influenced by several aneurysm-related anatomic factors. The anatomic features of aneurysms can be characterized by three-dimensional reconstructed images by use of rotational digital subtraction angiography (3D-DSA). The purpose of this study was to determine the anatomic factors that could help predict complete endosaccular packing of cerebral aneurysms by use of 3D-DSA and to design a simple scoring system to predict the difficulty of achieving complete occlusion of the aneurysm. METHODS: Forty-seven patients with 47 intracranial berry (<12 mm) aneurysms underwent 3D-DSA. Aneurysms were subsequently treated by endosaccular packing with coils. The following aneurysm-related anatomic parameters were measured on 3D-DSA images: largest diameter, neck size, dome-to-neck ratio, shape, and relationship to the neighboring artery. The relationship between each parameter and the rate of successful treatment was determined, and a score used to rate difficulty of attaining occlusion (ie, difficulty score) was developed on the basis of the identified predictors of successful treatment. Subsequently, we assessed the correlation between the score and the rate of successful occlusion. RESULTS: Four anatomic parameters correlated significantly with the rate of successful occlusion: neck size (P =.014), shape (P=.042), dome-to-neck ratio (P <.01), and relationship to neighboring artery (P=.025). The difficulty score based on two parameters (dome-to-neck ratio and relationship to neighboring artery) significantly correlated with the occlusion rate (r = 0.63, P <.01). CONCLUSION: In this population, the difficulty score based on 3D-DSA findings provides useful information for prediction of successful endovascular treatment for intracranial aneurysms.


Assuntos
Angiografia Digital , Transtornos Cerebrovasculares/diagnóstico , Aneurisma Intracraniano/diagnóstico , Adulto , Idoso , Idoso de 80 Anos ou mais , Angiografia Digital/métodos , Transtornos Cerebrovasculares/epidemiologia , Transtornos Cerebrovasculares/terapia , Embolização Terapêutica , Feminino , Humanos , Aneurisma Intracraniano/epidemiologia , Aneurisma Intracraniano/terapia , Masculino , Pessoa de Meia-Idade , Modelos Anatômicos , Análise Multivariada , Valor Preditivo dos Testes , Fatores de Risco , Estatística como Assunto
13.
AJNR Am J Neuroradiol ; 23(4): 711-5, 2002 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-11950674

RESUMO

BACKGROUND AND PURPOSE: Although neuroangiography remains the criterion standard standard for the detection of and surgical/interventional planning for cerebrovascular diseases, it usually requires that patients be confined to bed rest for several hours after angiography to prevent local complications. Decreasing catheter size has reduced the risk of hemorrhagic complications associated with early ambulation after angiography. For this study, we prospectively evaluated the clinical feasibility of a 3.3F catheter/sheath system for selective neuroangiography. METHODS: One hundred seventeen consecutive patients (49 men, 68 women; age range, 18-83 years; mean age, 56.9 years) underwent selective neuroangiography using 3.3F catheters. The exclusion criteria for this study included a subsequent surgical/neurointerventional procedure performed within 18 hours and necessity of arch aortography, which is routinely performed for the first examination of patients with ischemic cerebrovascular diseases. The procedure was evaluated prospectively in terms of success rate, compression time of the arterial puncture site, and periprocedural complications. RESULTS: Selective catheterization of the intended arteries was performed in 99% of the carotid arteries and 97.4% of the vertebral arteries. No neurologic complications or local hemorrhagic complications were observed. Manual compression time after the procedure ranged from 3 to 7 minutes (mean, 3.7 minutes), and patient bed rest after the procedure ranged from 2 to 3 hours (mean, 2.04 hours). CONCLUSION: Selective neuroangiography with a 3.3F catheter/sheath system is feasible and enables early ambulation in selected patients.


Assuntos
Cateterismo , Angiografia Cerebral/instrumentação , Transtornos Cerebrovasculares/diagnóstico por imagem , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Angiografia Cerebral/efeitos adversos , Estudos de Viabilidade , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Prospectivos
14.
Neurosurgery ; 50(3): 476-84; discussion 484-5, 2002 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-11841714

RESUMO

OBJECTIVE: Detection of a small residual lumen after coil embolization is often difficult because of the coil mass and the overlap of the cerebral arteries. The purpose of this study was to assess the usefulness of virtual endoscopic (VE) analysis of three-dimensional digital subtraction angiographic (DSA) images for evaluation of aneurysmal occlusion immediately after the procedure. METHODS: Twenty-seven intracranial aneurysms were treated with coil embolization using a three-dimensional DSA system. Biplane and rotational DSA scanning was performed before and immediately after the procedures. VE images were obtained at a separate workstation, after transfer of the rotational images. Two-dimensional (2D) DSA images and VE images obtained after the procedure were assessed with respect to aneurysmal occlusion. Morphological outcomes and other factors, including location, size, volumetric ratio (coil volume/aneurysm volume), and residual sites, were also evaluated. RESULTS: Seven aneurysms were evaluated as complete occlusion (CO) on both 2D DSA images and VE images. Twelve aneurysms exhibited residual lumina on both 2D DSA images and VE images. Five aneurysms were evaluated as CO on 2D DSA images and as incomplete occlusion on VE images. There were no recurrences among the aneurysms that were evaluated as CO on VE images. Two of five aneurysms that were evaluated as CO on 2D DSA images and as incomplete occlusion on VE images demonstrated regrowth in follow-up examinations. Residual sites and volumetric ratios were correlated with aneurysmal regrowth. CONCLUSION: VE imaging can demonstrate a residual lumen more frequently than can 2D DSA imaging and is useful for evaluating aneurysmal occlusion after coil embolization.


Assuntos
Angiografia Digital , Angiografia Cerebral , Embolização Terapêutica/instrumentação , Imageamento Tridimensional , Aneurisma Intracraniano/diagnóstico por imagem , Aneurisma Intracraniano/terapia , Interface Usuário-Computador , Adulto , Idoso , Idoso de 80 Anos ou mais , Angiografia Digital/normas , Angiografia Cerebral/normas , Equipamentos e Provisões , Feminino , Humanos , Imageamento Tridimensional/normas , Masculino , Pessoa de Meia-Idade , Período Pós-Operatório , Fatores de Tempo
15.
J Neurosurg ; 101(1): 159-62, 2004 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-15255268

RESUMO

A ruptured blisterlike aneurysm of the supraclinoid ICA rarely occurs. Nevertheless, it is recognized as a dangerous lesion because of the high risk of intraoperative bleeding associated with this lesion's wide fragile neck. There has been only one report of a blisterlike aneurysm treated by endosaccular packing after surgical wrapping. The authors describe the case of a ruptured blisterlike aneurysm with a pseudoaneurysm cavity, which was treated by coil embolization. This 63-year-old woman suffered a subarachnoid hemorrhage (SAH). Three cerebral aneurysms were identified on cerebral angiograms. A large saccular aneurysm at the ophthalmic portion of the right ICA was embolized with Guglielmi Detachable Coils (GDCs). Two small hemipherically shaped aneurysms on the C-2 and C-3 portions of the left ICA were observed conservatively. Thirteen days later, recurrent SAH was identified on computerized tomography scans. Angiography demonstrated the formation of a pseudoaneurysm from the aneurysm on the C-2 portion of the left ICA. Endosaccular embolization with GDCs was performed 40 days after admission. Disappearance of the pseudoaneurysm cavity and residual dome filling was seen immediately after the procedure. Follow-up angiography performed 9 months after embolization demonstrated complete obliteration of the aneurysm. This case illustrates that when treatment options for a blisterlike aneurysm with a pseudoaneurysm are unsuitable during the acute phase, coil embolization can be applied following progression of the lesion into a saccular aneurysm during the chronic stage.


Assuntos
Falso Aneurisma/terapia , Aneurisma Roto/terapia , Doenças das Artérias Carótidas/terapia , Artéria Carótida Interna , Embolização Terapêutica , Hemorragia Subaracnóidea/terapia , Falso Aneurisma/etiologia , Aneurisma Roto/complicações , Doenças das Artérias Carótidas/complicações , Feminino , Humanos , Pessoa de Meia-Idade , Hemorragia Subaracnóidea/etiologia , Fatores de Tempo
16.
Radiographics ; 24(6): 1637-53, 2004.
Artigo em Inglês | MEDLINE | ID: mdl-15537974

RESUMO

Intracranial dural arteriovenous fistulas (AVFs) can occur anywhere within the dura mater. Patients may be clinically asymptomatic or may experience symptoms ranging from mild symptoms to fatal hemorrhage, depending on the location (eg, cavernous sinus, transverse-sigmoid sinus, tentorium, superior sagittal sinus, anterior fossa) and venous drainage pattern of the AVF. In the past, dural AVFs have been treated with a variety of approaches, including surgical resection, venous clipping, transcatheter embolization, radiation therapy, or a combination of these treatments. Recent developments in catheter intervention now allow most patients to be cured with transcatheter embolization, although stereotactic radiation therapy is demonstrating good results in an increasing number of cases and surgery is still the preferred option in some cases. Familiarity with drainage patterns, the risk of aggressive symptoms, recent technical advances, and current treatment strategies is essential for the treatment of intracranial dural AVFs.


Assuntos
Malformações Vasculares do Sistema Nervoso Central/terapia , Cateterismo , Malformações Vasculares do Sistema Nervoso Central/fisiopatologia , Embolização Terapêutica , Hemodinâmica , Humanos
17.
J Neurol Sci ; 342(1-2): 192-6, 2014 Jul 15.
Artigo em Inglês | MEDLINE | ID: mdl-24863007

RESUMO

Cerebral malakoplakia is a very rare chronic inflammatory disease. We herein report the case of a 49-year-old female who presented with a slowly progressive speech disturbance and right hemiparesis. Computed tomography and magnetic resonance imaging showed irregular enhanced mass lesions with numerous scattered areas of calcification in the left insula, thalamus and basal ganglia. Histopathologically, the biopsy specimen showed basophilic laminated inclusion bodies and intracellular and extracellular calculospherules, usually with a typical targetoid appearance (Michaelis-Gutmann bodies). Treatment with antibiotics, bethanechol and ascorbic acid improved her symptoms in association with a decrease in the abnormal calcification and enhancement. The cerebral malakoplakia mimicked a brain tumor in terms of the patient's clinical course and neuroradiological image findings; however, it was successfully cured with medical treatment. This case provides evidence that the pathogenesis of cerebral malakoplakia is deeply tied to bacterial infection and that medical treatment is effective in cases of this disease.


Assuntos
Antibacterianos/uso terapêutico , Ácido Ascórbico/uso terapêutico , Betanecol/uso terapêutico , Malacoplasia/tratamento farmacológico , Encéfalo/patologia , Calcinose/patologia , Feminino , Humanos , Corpos de Inclusão/patologia , Malacoplasia/patologia , Pessoa de Meia-Idade , Agonistas Muscarínicos/uso terapêutico , Vitaminas/uso terapêutico
18.
Clin Neurol Neurosurg ; 123: 169-73, 2014 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-24968189

RESUMO

OBJECTIVE: Third nerve palsy (TNP) caused by a posterior communicating artery (PCoA) aneurysm is a well-known symptom of the condition, but the characteristics of unruptured PCoA aneurysm-associated third nerve palsy have not been fully evaluated. The aim of this study was to analyze the anatomical features of PCoA aneurysms that caused TNP from the viewpoint of the relationship between the ICA and the skull base. METHODS: Forty-eight unruptured PCoA aneurysms were treated surgically between January 2008 and September 2013. The characteristics of the aneurysms were evaluated. RESULTS: Thirteen of the 48 patients (27%) had a history of TNP. The distance between the ICA and the anterior-posterior clinoid process (ICA-APC distance) was significantly shorter in the TNP group (p<0.01), but the maximum size of the aneurysms was not (p=0.534). CONCLUSION: Relatively small unruptured PCoA aneurysms can cause third nerve palsy if the ICA runs close to the skull base.


Assuntos
Aneurisma Roto/patologia , Encéfalo/patologia , Aneurisma Intracraniano/patologia , Doenças do Nervo Oculomotor/etiologia , Doenças do Nervo Oculomotor/patologia , Base do Crânio/patologia , Adulto , Idoso , Idoso de 80 Anos ou mais , Aneurisma Roto/complicações , Feminino , Humanos , Aneurisma Intracraniano/complicações , Masculino , Pessoa de Meia-Idade
19.
Neurol Med Chir (Tokyo) ; 52(9): 631-3, 2012.
Artigo em Inglês | MEDLINE | ID: mdl-23006873

RESUMO

A 74-year-old woman was admitted to our hospital due to severe nuchal pain and occipitalgia. Neurological examination found neck stiffness but no throat pain or dysphagia. Blood examination showed slight elevation of white blood cell count, but C-reactive protein level was normal. Cerebrospinal fluid examination found no abnormalities. Computed tomography (CT) and magnetic resonance (MR) imaging demonstrated no abnormalities in the brain. Cervical CT showed a small calcification in front of the C1 body. Cervical T(2)-weighted MR imaging showed a high intensity area in front of the upper cervical vertebral body from C1 to C4, suggesting inflammation of the longus colli muscles. We diagnosed acute calcific prevertebral tendonitis. She was administered nonsteroidal anti-inflammatory drugs. Her symptoms gradually improved and she was discharged without neurological deficit 8 days after admission. It is important to be aware of the possibility of this rare disease in a patient with severe occipitalgia but no sign of intracerebral lesion.


Assuntos
Calcinose/diagnóstico , Tendinopatia/diagnóstico , Cefaleia do Tipo Tensional/diagnóstico , Idoso , Anti-Inflamatórios não Esteroides/uso terapêutico , Proteína C-Reativa/análise , Diagnóstico Diferencial , Feminino , Humanos , Imageamento por Ressonância Magnética , Músculos do Pescoço/patologia , Cervicalgia/etiologia , Tendinopatia/tratamento farmacológico , Tendinopatia/patologia , Tomografia Computadorizada por Raios X
20.
Neurol Med Chir (Tokyo) ; 51(9): 645-8, 2011.
Artigo em Inglês | MEDLINE | ID: mdl-21946729

RESUMO

A 36-year-old female patient was admitted to our hospital with a rare case of aneurysm at the origin of the accessory middle cerebral artery (MCA) manifesting as severe headache and vomiting. Neurological examination did not detect any abnormalities or consciousness disturbance. Computed tomography demonstrated diffuse subarachnoid hemorrhage. Magnetic resonance angiography showed an aneurysm in the horizontal portion of the left anterior cerebral artery (A(1)). Digital subtraction angiography and three-dimensional digital subtraction angiography demonstrated a saccular aneurysm originating at the junction of the left A(1) and accessory MCA. Another accessory MCA originated at the proximal portion of the left A(2) without an aneurysm. Two accessory MCAs were found on the left. Neck clipping was performed via a left pterional approach. One month after admission, she was discharged without neurological deficits.


Assuntos
Aneurisma Roto/diagnóstico , Artéria Cerebral Anterior/patologia , Aneurisma Intracraniano/diagnóstico , Artéria Cerebral Média/patologia , Hemorragia Subaracnóidea/diagnóstico , Hemorragia Subaracnóidea/patologia , Adulto , Aneurisma Roto/patologia , Aneurisma Roto/cirurgia , Artéria Cerebral Anterior/cirurgia , Feminino , Humanos , Aneurisma Intracraniano/cirurgia , Angiografia por Ressonância Magnética , Hemorragia Subaracnóidea/fisiopatologia , Resultado do Tratamento
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