Detalhe da pesquisa
1.
In Vitro Pharmacological Characterization of Buprenorphine, Samidorphan, and Combinations Being Developed as an Adjunctive Treatment of Major Depressive Disorder.
J Pharmacol Exp Ther
; 367(2): 267-281, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30108159
2.
Advancing New Chemical Modalities into Clinical Studies.
ACS Med Chem Lett
; 13(11): 1691-1698, 2022 Nov 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36385931
3.
A review of clinical efficacy data supporting emergency use authorization for COVID-19 therapeutics and lessons for future pandemics.
Clin Transl Sci
; 15(10): 2279-2292, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35929015
4.
Insulin and glucose metabolism with olanzapine and a combination of olanzapine and samidorphan: exploratory phase 1 results in healthy volunteers.
Neuropsychopharmacology
; 47(3): 696-703, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34887529
5.
Identification of druggable host targets needed for SARS-CoV-2 infection by combined pharmacological evaluation and cellular network directed prioritization both in vitro and in vivo.
bioRxiv
; 2022 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33907750
6.
Identification of potent inhibitors of SARS-CoV-2 infection by combined pharmacological evaluation and cellular network prioritization.
iScience
; 25(9): 104925, 2022 Sep 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-35992305
7.
Early Returns on Small Molecule Therapeutics for SARS-CoV-2.
ACS Infect Dis
; 7(6): 1298-1302, 2021 06 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33417425
8.
Recognition of Divergent Viral Substrates by the SARS-CoV-2 Main Protease.
ACS Infect Dis
; 7(9): 2591-2595, 2021 09 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34437808
9.
A multi-pronged approach targeting SARS-CoV-2 proteins using ultra-large virtual screening.
iScience
; 24(2): 102021, 2021 Feb 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-33426509
10.
A Multi-Pronged Approach Targeting SARS-CoV-2 Proteins Using Ultra-Large Virtual Screening.
ChemRxiv
; 2020 Jul 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-33200116
11.
Flipped out: structure-guided design of selective pyrazolylpyrrole ERK inhibitors.
J Med Chem
; 50(6): 1280-7, 2007 Mar 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-17300186
12.
Discovery of Thienoimidazole-Based HCV NS5A Genotype 1a and 1b Inhibitors.
ACS Med Chem Lett
; 5(3): 240-3, 2014 Mar 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-24900811
13.
Structure-guided design of potent and selective pyrimidylpyrrole inhibitors of extracellular signal-regulated kinase (ERK) using conformational control.
J Med Chem
; 52(20): 6362-8, 2009 Oct 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-19827834