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Ann Biol Clin (Paris) ; 74(1): 103-5, 2016.
Artigo em Francês | MEDLINE | ID: mdl-26878614

RESUMO

Light chain multiple myeloma is a hematologic malignancy characterized by an excess of tumor plasma cells in the bone marrow and a monoclonal light chain in blood. It is generally diagnosed in patients aged 60-75 years old. Hypercalcemia, anemia, kidney failure, and bone pains are the main clinical and biological signs. Here is an atypical case report about a 30 year-old man who was diagnosed a light chain multiple myeloma. This patient had been suffering from back pain for 5 months. Osteolytic lesions were discovered on X-rays prescribed by the family practitioner. Admitted to the Emergency department, all blood tests showed results within the normal range. The serum protein electrophoresis was also normal. Only the urine analysis showed proteinuria. The urine immunofixation electrophoresis showed a massive κ light chain. The bone marrow aspiration cell count confirmed the myeloma diagnosis with an infiltration of dystrophic plasma cells. The patient was transferred to the hematology ward of Necker Hospital for treatment of light chain myeloma.


Assuntos
Traumatismos em Atletas/etiologia , Dor nas Costas/etiologia , Futebol Americano/lesões , Cadeias kappa de Imunoglobulina/metabolismo , Mieloma Múltiplo/diagnóstico , Adulto , Traumatismos em Atletas/diagnóstico , Diagnóstico Diferencial , Humanos , Masculino , Movimento , Mieloma Múltiplo/complicações , Mieloma Múltiplo/metabolismo , Osteólise/diagnóstico , Osteólise/etiologia
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