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1.
Clin Diabetes ; 42(2): 257-265, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38694243

RESUMO

This study examined the association between persistence to basal insulin and clinical and economic health outcomes. The question of whether a persistence measure for basal insulin could be leveraged in quality measurement was also explored. Using the IBM-Truven MarketScan Commercial and Medicare Supplemental Databases from 1 January 2011 to 31 December 2015, a total of 14,126 subjects were included in the analyses, wherein 9,898 (70.1%) were categorized as persistent with basal insulin therapy. Basal insulin persistence was associated with lower A1C, fewer hospitalizations and emergency department visits, and lower health care expenditures. Quality measures based on prescription drug claims for basal insulin are feasible and should be considered for guiding quality improvement efforts.

2.
J Am Pharm Assoc (2003) ; 63(1): 50-57.e2, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-35688776

RESUMO

BACKGROUND: Anecdotal evidence suggests that gender inequity persists in academic pharmacy. To date, there are limited published data about the perception of gender inequity in academic pharmacy. OBJECTIVE: The objective of this project was to determine themes associated with gender inequity perceptions in social and administrative science faculty from 2 national pharmacy organizations. METHODS: A gender equity task force comprising 13 members from Social and Administrative Sciences (SAS) sections of the American Pharmacists Association and the American Association of Colleges of Pharmacy was formed. The task force designed a semistructured interview guide comprising questions about demographics and core areas where inequities likely exist. When the survey invitation was sent to faculty members of the SAS sections via Qualtrics, faculty indicated whether they were willing to be interviewed. Interviews were conducted by 2 members of the task force via video conferencing application. The interviews were transcribed. Topic coding involving general categorization by theme followed by refinement to delineate subcategories was used. Coding was conducted independently by 3 coders followed by consensus when discrepancies were identified. RESULTS: A total of 21 faculty participated in the interviews. Respondents were primarily female (71%), were white (90%), had Doctor of Philosophy as their terminal degree (71%), and were in nontenure track positions (57%). Most respondents (90%) experienced gender inequity. A total of 52% reported experiencing gender inequity at all ranks from graduate student to full professor. Four major themes were identified: microaggression (57%), workload (86%), respect (76%), and opportunities (38%). Workload, respect, and opportunities included multiple subthemes. CONCLUSION: Faculty respondents perceive gender inequities in multiple areas of their work. Greater inequity perceptions were present in areas of workload and respect. The task force offers multiple recommendations to address these inequities.


Assuntos
Educação em Farmácia , Farmácia , Estudantes de Farmácia , Humanos , Feminino , Estados Unidos , Equidade de Gênero , Docentes
3.
J Am Pharm Assoc (2003) ; 62(2): 537-540, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-34736866

RESUMO

BACKGROUND: The pharmacy marketplace has shifted considerably in recent years. The decline in job openings and stagnant growth in wages, along with public reports about adverse working conditions for some pharmacists, may have tarnished the optimism of young pharmacists toward the profession of pharmacy. OBJECTIVE: The objective of this study was to analyze the trend among graduating student pharmacists regarding their positivity toward a career in pharmacy. METHODS: Data for this study were extracted from the Graduating Student Survey that is maintained by the American Association of Colleges of Pharmacy. This set of analyses focused on respondents' agreement with the statement "If I was starting my college career over again, I would choose to study pharmacy." Descriptive statistics are reported for this item across 2014 to 2021, and chi-square analyses were used to compare the trend in agreement rates across years and to compare responses between public and private colleges of pharmacy. RESULTS: Survey response rates ranged from 71.1%-80.2% across years and categories (public vs. private). Across 2014-2021, there was an overall decline in the percentage of graduating student pharmacists who indicated that they would choose pharmacy again if they were starting over in college with the greatest decline occurring after 2016. Across all colleges, agreement declined from 81.8% (2014) to 72.2% (2021) (χ2 = 398.2; P < 0.001). The percentage of agreement responses for private college graduates declined from 80.7% (2014) to 74.8% (2021) whereas the percentage of agreement responses for public college graduates declined from 83.0% (2014) to 69.8% (2020). In 2021, public college graduates had lower agreement than private college graduates (χ2 = 33.8; P < 0.001). CONCLUSION: The positivity of graduating student pharmacists toward a career in pharmacy has deteriorated since 2014. Further investigation of this phenomenon is warranted.


Assuntos
Educação em Farmácia , Farmácia , Estudantes de Farmácia , Humanos , Farmacêuticos , Faculdades de Farmácia
4.
J Am Pharm Assoc (2003) ; 63(4): 986-987, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37479394
6.
J Am Pharm Assoc (2003) ; 57(3): 311-317, 2017.
Artigo em Inglês | MEDLINE | ID: mdl-28285064

RESUMO

OBJECTIVES: To identify patients' understanding of what constitutes a "quality pharmacy" and to obtain their feedback regarding the development and use of the pharmacy star rating model, a pharmacy-specific aggregate performance score based on the Centers for Medicare and Medicaid Services' Medicare Star Rating. DESIGN: Prospective cross-sectional study. SETTING AND PARTICIPANTS: Focus groups were conducted in Arizona, California, Mississippi, Maryland, and the District of Columbia, and one-on-one interviews were conducted in Indiana. Eligible patients were required to routinely use a community pharmacy. MAIN OUTCOME MEASURES: Consumer insights on their experiences with their pharmacies and their input on the pharmacy star rating model were attained. Key themes from the focus groups and interviews were obtained through the use of qualitative data analyses. RESULTS: Forty-nine subjects from 5 states and DC participated in 6 focus groups and 4 one-on-one interviews. Eighty-eight percent of participants reported currently taking at least 1 medication, and 87% reported having at least 1 health condition. The 7 themes identified during qualitative analysis included patient care, relational factors for choosing a pharmacy, physical factors for choosing a pharmacy, factors related to use of the pharmacy star rating model, reliability of the pharmacy star rating model, trust in pharmacists, and measures of pharmacy quality. Most participants agreed that the ratings would be useful and could aid in selecting a pharmacy, especially if they were moving to a new place or if they were dissatisfied with their current pharmacy. CONCLUSION: Pharmacy quality measures are new to patients. Therefore, training and education will need to be provided to patients, as pharmacies begin to offer additional clinical services, such as medication therapy management and diabetes education. The use of the pharmacy star rating model was dependent on the participants' situation when choosing a pharmacy.


Assuntos
Serviços Comunitários de Farmácia/estatística & dados numéricos , Farmácias/estatística & dados numéricos , Indicadores de Qualidade em Assistência à Saúde/estatística & dados numéricos , Estudos Transversais , Estudos de Avaliação como Assunto , Feminino , Grupos Focais , Humanos , Masculino , Medicaid/estatística & dados numéricos , Medicare/estatística & dados numéricos , Pessoa de Meia-Idade , Percepção , Farmacêuticos/estatística & dados numéricos , Estudos Prospectivos , Estados Unidos
7.
J Am Pharm Assoc (2003) ; 56(5): 549-54, 2016.
Artigo em Inglês | MEDLINE | ID: mdl-27521167

RESUMO

OBJECTIVES: The star rating system implemented by Medicare has the potential to positively affect patient health and may have financial implications for community pharmacies. Learning from owners of community pharmacies with high performance on these quality measures may help us to identify and further understand factors contributing to their success. This study described high-performing community pharmacy owners' current awareness and knowledge of star ratings, attitudes toward star ratings and performance measurement, and initiatives being offered in pharmacies that aim to improve the quality of care. METHODS: Qualitative interviews with owners of independent community pharmacies were conducted in Spring 2015. Fifteen community pharmacies with high performance on the star rating measures were invited to participate. Recruitment did not end until the saturation point had been reached. All interviews were transcribed verbatim. Interview data were analyzed with the use of ATLAS.ti by 2 coders trained in thematic analysis. Krippendorf's alpha was calculated to assess intercoder reliability. RESULTS: Ten high-performing pharmacy owners participated. Analysis identified 8 themes, which were organized into the following categories: 1) current awareness and knowledge (i.e., superficial or advanced knowledge); 2) attitudes toward star ratings (positive perceptions, skeptical of performance rewards, and lack a feeling of control); and 3) pharmacy initiatives (personal patient relationships, collaborative employee relationships, and use of technology). Intercoder reliability was good overall. CONCLUSION: Interviews with high-performing pharmacies suggested that awareness of the star rating measures, overall positive attitudes toward the star ratings, the relationships that pharmacy owners have with their patients and their employees, and the use of technology as a tool to enhance patient care may contribute to high performance on the star rating measures. Future research is needed to determine if and how these constructs are associated with pharmacy performance in a larger population.


Assuntos
Serviços Comunitários de Farmácia/normas , Propriedade , Indicadores de Qualidade em Assistência à Saúde , Qualidade da Assistência à Saúde , Serviços Comunitários de Farmácia/organização & administração , Feminino , Humanos , Entrevistas como Assunto , Masculino , Medicare , Variações Dependentes do Observador , Melhoria de Qualidade , Estados Unidos
8.
Am J Pharm Educ ; 87(4): ajpe9049, 2023 04.
Artigo em Inglês | MEDLINE | ID: mdl-36332918

RESUMO

Objective. The majority of practicing pharmacists and student pharmacists are women. However, instruments to assess perceptions of gender equity within pharmacy academia are not available. The objective of this research was to describe the psychometric analysis of a questionnaire developed to assess gender equity by a Gender Equity Task Force and to report reliability and validity evidence.Methods. A questionnaire with 21 items addressing the teaching, research, service, advancement, mentoring, recruitment, and gender of college leaders was created. The survey was distributed via email in December 2020 to all social and administrative science section members of two professional associations. Rasch analysis was performed to evaluate the reliability and validity evidence for the questionnaire.Results. After reverse coding, all items met parameters for unidimensionality necessary for Rasch analysis. Once adjacent categories were merged to create a 3-point scale, the scale and items met parameters for appropriate functionality. Items were ordered hierarchically in order of difficulty. The modified instrument and scale can be treated as interval level data for future use.Conclusion. This analysis provides reliability and validity evidence supporting use of the gender equity questionnaire in the social and administrative academic pharmacy population if recommended edits such as the 3-point scale are used. Future research on gender equity can benefit from use of a psychometrically sound questionnaire for data collection.


Assuntos
Educação em Farmácia , Farmácia , Humanos , Masculino , Feminino , Reprodutibilidade dos Testes , Equidade de Gênero , Inquéritos e Questionários , Psicometria/métodos
9.
J Am Pharm Assoc (2003) ; 52(3): 324-32, 2012.
Artigo em Inglês | MEDLINE | ID: mdl-22618972

RESUMO

OBJECTIVES: To develop and test a tool for obtaining patient evaluations of the quality of pharmacy services provided in ambulatory settings. DESIGN: Descriptive, exploratory, nonexperimental study. SETTING: United States from June 1, 2006, through May 31, 2007. PARTICIPANTS: 895 individuals who obtained prescription medications from participating pharmacies. INTERVENTION: Items were evaluated for inclusion in composite scales based on factor analysis and frequency of missing data. Standard psychometric methods were used to assess the reliability and construct validity of the resulting three composite and three global-item measures. MAIN OUTCOME MEASURE: Patient assessment of the quality of ambulatory care pharmacy services. RESULTS: Confirmatory factor analysis indicated that a subset of 15 items measuring three aspects of pharmacy services (General Staff Communication, Health- and Medication-Focused Communication, and Clarity of Written Information about Medications) provided excellent fit to the data. Cronbach's alphas for these scales were greater than 0.80. The three scales and corresponding three global ratings of quality reliably described differences among providers of pharmacy services. CONCLUSION: These data provide support for the reliability and validity of the Consumer Assessment of Pharmacy Services survey. Although preliminary results regarding reliability and validity are promising, further study of the survey is warranted.


Assuntos
Comportamento do Consumidor , Assistência Farmacêutica , Adulto , Idoso , Assistência Ambulatorial , Prescrições de Medicamentos , Análise Fatorial , Feminino , Pesquisas sobre Atenção à Saúde , Humanos , Masculino , Pessoa de Meia-Idade , Assistência Farmacêutica/normas , Psicometria , Reprodutibilidade dos Testes , Estados Unidos
10.
Ann Pharmacother ; 45(12): 1582-4, 2011 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-22045907

RESUMO

The federal government is increasing its push for a high-value health care system by increasing transparency and accountability related to quality. The Medicare program has begun to publicly rate the quality of Medicare plans, including prescription drug plans, and is transforming its payment policies to reward plans that deliver the highest levels of quality. These policies will have a cascade effect on pharmacies and pharmacists as the Medicare plans look for assistance in improving the quality of medication use. This commentary describes the Medicare policies directed toward improvement of quality and their effect on pharmacy payment and opportunities for pharmacists to affirm their role in a high-quality medication use system.


Assuntos
Atenção à Saúde/economia , Política de Saúde/economia , Medicare/economia , Garantia da Qualidade dos Cuidados de Saúde/economia , Centers for Medicare and Medicaid Services, U.S. , Humanos , Farmácias/economia , Farmacêuticos/economia , Medicamentos sob Prescrição/economia , Estados Unidos
11.
J Am Pharm Assoc (2003) ; 51(4): 544-50, 2011.
Artigo em Inglês | MEDLINE | ID: mdl-21752779

RESUMO

OBJECTIVES: To describe the five Phase I Pharmacy Quality Alliance (PQA) demonstration projects and discuss lessons learned across the projects. DESIGN: Descriptive nonexperimental study. SETTING: United States from July 2008 to November 2009. PARTICIPANTS: Community pharmacies from five states. INTERVENTION: Pharmacies viewed their performance scores on a reporting website and provided feedback. MAIN OUTCOMES MEASURES: Pharmacy performance scores and pharmacist feedback about the scores and reporting websites. RESULTS: Considerable variation was found in the pharmacy performance scores. Some pharmacies did not have enough patients taking medications that were included in specific performance measures. Use of a website to report pharmacy performance was feasible across several different approaches. PQA has developed measures of pharmacy performance that can be used in programs intended to report pharmacy performance. CONCLUSION: It is feasible to calculate pharmacy performance scores and create Web-based pharmacy performance reports to provide feedback to community pharmacists. Further development of pharmacy performance reporting should occur.


Assuntos
Serviços Comunitários de Farmácia/normas , Serviços Comunitários de Farmácia/organização & administração , Coleta de Dados , Retroalimentação , Humanos , Internet , Garantia da Qualidade dos Cuidados de Saúde , Estados Unidos
12.
Am J Manag Care ; 27(10): 425-431, 2021 10.
Artigo em Inglês | MEDLINE | ID: mdl-34668671

RESUMO

OBJECTIVES: To evaluate the impact of a collaborative effort of a Medicare Advantage and prescription drug (MAPD) plan and community pharmacies to improve vaccination rates for pneumonia and influenza. STUDY DESIGN: This quasiexperimental, cluster-randomized intervention study used MAPD data to assess the impact of community pharmacists on vaccination rates. Pharmacies in specific regions (districts) were randomly assigned to intervention or control groups. Intervention pharmacies received reports of patients with a gap in influenza (aged 19-89 years) and/or pneumococcal (aged 65-89 years) vaccinations based on medical and pharmacy claims history. Vaccine-naïve patients were offered vaccinations. METHODS: The vaccination rates for the previously vaccine-naïve patients utilizing intervention and control pharmacies were compared 6 months post randomization. Inverse probability weighted hierarchical generalized linear models determined the odds of receiving pneumonia and influenza vaccinations for intervention and control groups, controlling for baseline clinical and demographic characteristics. RESULTS: Intervention and control groups had similar ages in the pneumococcal older-adult cohort (mean age, 73.0 vs 73.4 years, respectively; P = .1255). The intervention group was older than the control group in the influenza cohort (mean age, 67.7 vs 66.4 years, respectively; P = .0006). Slightly more than half of each cohort were women, and the proportion of women was not significantly different between the intervention and control groups in each cohort. In multivariable analyses, intervention pharmacies were associated with higher odds of delivering pneumococcal (odds ratio [OR], 1.91; 95% CI, 1.26-2.87) and influenza (OR, 2.18; 95% CI, 1.37-3.46) vaccinations than control pharmacies. CONCLUSIONS: A health plan-enabled, pharmacist-led intervention was effective in increasing the number of older adults receiving pneumococcal vaccination and individuals receiving influenza vaccination.


Assuntos
Serviços Comunitários de Farmácia , Influenza Humana , Medicare Part C , Farmácias , Farmácia , Idoso , Feminino , Humanos , Influenza Humana/tratamento farmacológico , Influenza Humana/prevenção & controle , Estados Unidos , Vacinação
13.
Am J Pharm Educ ; 84(3): 7700, 2020 03.
Artigo em Inglês | MEDLINE | ID: mdl-32313281

RESUMO

The quality of educational programs, including Doctor of Pharmacy (PharmD) programs, has largely escaped the societal trend towards public reporting. Recent criticisms of pharmacy academia by practitioners should prompt us to reexamine how the quality of pharmacy education is measured and reported to the public. In supporting greater transparency related to quality, important questions that should be addressed include: Is the current public reporting of quality indicators for pharmacy schools sufficient for determining the quality of education provided by a school? Can a quality rating system be developed that will not only provide a valid assessment of quality, but also be easy to interpret by potential applicants and employers? The intent of this commentary is to initiate a discussion centered around this issue and to encourage the development of a new measure of pharmacy school quality.


Assuntos
Educação em Farmácia , Assistência Farmacêutica , Farmácias , Estudantes de Farmácia , Humanos , Faculdades de Farmácia
14.
Mil Med ; 185(5-6): e894-e899, 2020 06 08.
Artigo em Inglês | MEDLINE | ID: mdl-32173760

RESUMO

INTRODUCTION: As the healthcare system shifts from fee-for service toward value-driven healthcare, interest has grown in medication-related quality metrics to evaluate quality and value within the healthcare system. While the Defense Health Agency (DHA) has taken steps to align healthcare quality measures across the enterprise, the extent to which DHA utilizes pharmacy quality measures (PQMs) or evaluates the quality of direct and purchased pharmacy care is unknown. MATERIALS AND METHODS: A comparison was made between existing PQMs utilized by DHA and all measures published and endorsed by the Pharmacy Quality Alliance (PQA), a recognized, PQM standard-setting organization. We also compared DHA PQMs to those used within the Medicare Part D Star Rating Program. RESULTS: DHA has implemented 10 (28%) of the 36 PQA measures available for evaluation as of August 2019. Of the five measures included in the 2020 CMS Part D Star Rating program, DHA has currently implemented four (80%) of the measures. DHA has implemented 3 of the 5 (60%) PQA CMS Display Measures, and 5 of 9 (56%) PQA CMS Patient Safety Report Measures that are not part of the Star Ratings, but that are used to benchmark and provide feedback to health plans. CONCLUSION: Opportunities exist within the DHA to leverage PQMs to evaluate the quality of pharmaceutical care, build trust with beneficiaries by increasing transparency, and maintain parity with the civilian healthcare system. Existing models and commercially available technology could be considered to rapidly operationalize the use of PQMs within the MHS.


Assuntos
Serviços de Saúde Militar , Farmácia , Idoso , Humanos , Medicare , Conduta do Tratamento Medicamentoso , Assistência Farmacêutica , Indicadores de Qualidade em Assistência à Saúde , Estados Unidos
15.
J Am Pharm Assoc (2003) ; 49(2): 154-63, 2009.
Artigo em Inglês | MEDLINE | ID: mdl-19289341

RESUMO

OBJECTIVE: To describe methods for measuring health care quality and how these methods can be applied to the measurement of pharmacy quality and to describe ways of stimulating the use of quality improvement methods in pharmacy. SUMMARY: The health care system is moving toward value-based purchasing of professional services, which is also known as value-driven health care. Value is often described as the balance between quality and costs, and thus, we can enhance value by improving quality while controlling costs. Although community pharmacies have not experienced the demand for evidence of quality and value, this is likely to change in the near future as the federal government and private purchasers expand their search for quality-related evidence to all sectors of health care. PQA, a pharmacy quality alliance, has been created to coordinate the efforts of numerous pharmacy stakeholders in developing measures of pharmacy quality and in educating pharmacists about quality improvement methods. In addition to educational strategies for stimulating quality improvement, the pharmacy sector is likely to experience regulatory changes that mandate quality improvement, public reports on the quality of individual pharmacies, and pay-for-performance systems that reward pharmacies for achieving higher levels of quality. CONCLUSION: All stakeholders in pharmacy (i.e., pharmacists, owners, managers, technicians, benefits managers) must become more aware of the movement toward value-driven health care and the ramifications for pharmacy practice. Community pharmacists will soon see an increased demand for evidence of quality and value as this sector is integrated within the broader framework for value-driven health care.


Assuntos
Assistência Farmacêutica/normas , Farmácias/normas , Indicadores de Qualidade em Assistência à Saúde , Gestão da Qualidade Total/métodos , Erros de Medicação/prevenção & controle , Assistência Farmacêutica/organização & administração , Assistência Farmacêutica/tendências , Farmácias/organização & administração , Farmácias/tendências
16.
J Am Pharm Assoc (2003) ; 49(2): 212-9, 2009.
Artigo em Inglês | MEDLINE | ID: mdl-19289348

RESUMO

OBJECTIVE: To report on the status of the pilot work of PQA, a pharmacy quality alliance, to develop and test performance metrics of pharmacy services for use in quality improvement, benchmarking, and pay-for-performance benchmarks. DESIGN: Observational cohort study. SETTING: Three health plans (commercial, Medicare and Medicaid) located in the northeastern United States and one nationwide prescription drug plan. PATIENTS: Pharmacies of health plans with membership ranging from approximately 3,330 to nearly 1.7 million members. INTERVENTION: Pharmaceutical claims data for prescriptions dispensed at community pharmacies were analyzed. MAIN OUTCOME MEASURES: Not applicable. RESULTS: The four plans had pharmacy networks ranging from 653 to 53,153 pharmacies. When using a minimum sample of 30 members per measure, less than 10% of the pharmacies within the plans' networks were evaluable for all measures except the measure of high-risk drugs in the elderly. The measure for high-risk drugs in the elderly had 6,210 evaluable pharmacies in a network of 53,153. The measures for high-risk drugs in the elderly and medication adherence appear to have the greatest potential for use as performance measures in that they show room for improvement and variation among pharmacies. CONCLUSION: The ideal performance measure is relevant, scientifically sound, and feasible. Several of the measures that underwent testing possessed some, if not all, of the properties of an ideal performance measure. Strategies for aggregating data across health and drug plans may be useful for overcoming sample size challenges.


Assuntos
Serviços Comunitários de Farmácia/normas , Seguro de Serviços Farmacêuticos/economia , Programas Nacionais de Saúde/economia , Garantia da Qualidade dos Cuidados de Saúde , Estudos de Coortes , Serviços Comunitários de Farmácia/economia , Serviços Comunitários de Farmácia/organização & administração , Humanos , Revisão da Utilização de Seguros , Seguro de Serviços Farmacêuticos/normas , Conduta do Tratamento Medicamentoso/economia , Conduta do Tratamento Medicamentoso/organização & administração , Conduta do Tratamento Medicamentoso/normas , Programas Nacionais de Saúde/organização & administração , Projetos Piloto , Medicamentos sob Prescrição/economia
17.
J Cardiovasc Comput Tomogr ; 13(4): 226-233, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-30737152

RESUMO

BACKGROUND: Aim of this study was to assess the accuracy of ventricular septal defects (VSD) using high pitch computed tomography angiography (CTA) of the chest in children below 1 year of age, compared to the intraoperative findings and echocardiography. METHODS: Out of 154 patients that underwent Dual-Source CTA of the chest using a high-pitch protocol at low tube voltages (70-80 kV), 55 underwent surgical repair of a VSD (median age 8 days, range 1-348 days). The margins of the VSDs and their relation to the surrounding structures were reproduced by en-face views using multiplanar reformations (MPR). Absolute diameter, normalized area and relative area compared to the aortic valve annulus were used for discrimination between restrictive and non-restrictive defects. Localization was classified into four subtypes. The results were compared to two-dimensional echocardiography and intraoperative findings. RESULTS: Median absolute size of VSDs did not differ significantly between CTA-measurements (10.8 mm, range 2.8-18.1 mm) and intraoperative findings (12.0 mm, 3.0-25.0 mm, p = 0.09). Echocardiographic values were significantly lower (9.6 mm, 3.0-18.5 mm, both p < 0.01). The classification of the location and orientation matched the intraoperative situs in 96.4% of all cases using CT and in 87.3% using echocardiography. Echocardiography missed the relation to valves in 11% of all cases. Pre-interventional sensitivity and specificity for detection of a VSD were 97.2/98.9% compared to echocardiography. Median radiation dose was 0.32 mSv (range 0.12-2.00 mSv) and differed significantly between second and third generation Dual-Source CT (0.43 vs. 0.22 mSv, p = 0.003). CONCLUSION: Size and subtype of VSDs can be accurately assessed by CTA of the chest in patients with complex congenital heart defects at a very low radiation dose.


Assuntos
Angiografia por Tomografia Computadorizada , Angiografia Coronária/métodos , Comunicação Interventricular/diagnóstico por imagem , Fatores Etários , Ecocardiografia , Comunicação Interventricular/cirurgia , Humanos , Lactente , Recém-Nascido , Valor Preditivo dos Testes , Doses de Radiação , Exposição à Radiação , Reprodutibilidade dos Testes , Estudos Retrospectivos
18.
Clin Ther ; 29(1): 177-80, 2007 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-17379058

RESUMO

BACKGROUND: With recent media attention to drug safety, patients may have heightened concerns about the side effects of medications that may affect their compliance with treatment. OBJECTIVES: The purpose of this study was to determine the proportion of patients with type 2 diabetes mellitus who perceived having experienced side effects of antihyperglycemic medications, the proportion of these patients who communicated their concerns to physicians, and the potential association between the perception of experiencing side effects and adherence to medication regimens. METHODS: Patients with diabetes were identified through the claims of a Midwest US managed care organization, using Health Plan Employer Data and Information Set criteria. Questionnaires were mailed to randomly selected patients. Patients receiving oral antihyperglycemic medications were selected as prospective subjects. Patients were excluded if they were receiving insulin. RESULTS: The responses of 445 patients meeting the study criteria were collected and analyzed. The subjects were pre-dominantly white, with a mean (SD) age of 56 (11) years and a mean duration of diabetes of 7.3 (8.8) years. One hundred forty-eight (33%) subjects reported a perception of having experienced side effects of antihyperglycemic medication; 126 (85%) subjects reported that they had communicated these concerns to their physicians. Analysis of the subjects' responses indicated an association between the perception of having experienced side effects and nonadherence to antihyperglycemic medication regimens (beta=-0.15; P < 0.010). CONCLUSIONS: Nearly one third of subjects with diabetes receiving oral noninsulin antihyperglycemic medications reported a perception of having experienced medication-related side effects. Despite the large portion of subjects who reported that they had communicated these concerns to their physicians, the perception of experiencing medication-related side effects was significantly associated with nonadherence to antihyperglycemic drug regimens.


Assuntos
Diabetes Mellitus Tipo 2/tratamento farmacológico , Conhecimentos, Atitudes e Prática em Saúde , Hipoglicemiantes/efeitos adversos , Cooperação do Paciente , Idoso , Comunicação , Feminino , Inquéritos Epidemiológicos , Humanos , Hipoglicemiantes/uso terapêutico , Masculino , Programas de Assistência Gerenciada , Meios de Comunicação de Massa , Pessoa de Meia-Idade , Relações Médico-Paciente , Análise de Regressão
19.
Ann Pharmacother ; 41(11): 1792-7, 2007 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-17925497

RESUMO

BACKGROUND: Although visual analog scales (VAS) have been used frequently in outcomes research, there is little evidence regarding the validity of this scale for measuring medication adherence. OBJECTIVE: To determine whether a VAS self-report measure of medication adherence is concordant with claims-based measurement of adherence. METHODS: A mail survey was conducted in 2005 of persons with diabetes. Prescription claims were obtained for the 1985 survey respondents who used oral diabetes medications and lipid-modifying drugs. The self-reported measure of adherence was a VAS scored 0-100%, and the claims-based measure was the continuous measure of medication gaps (CMG), reverse-coded to yield a score of 0-100%. Dichotomous measures (highly adherent vs poorly adherent) were also created from the VAS and CMG using a cutoff value of 80%. For diabetes and lipid-modifying drugs, the scores on the VAS and CMG (continuous versions) were compared using a Pearson correlation coefficient, while the concordance of the dichotomous versions of the measures was compared using the kappa coefficient. RESULTS: The mean +/- SD for the VAS and CMG for oral diabetes drugs were 95.9 +/- 9.2 and 84.1 +/- 19.2, respectively, and for lipid-modifying drugs, 95.2 +/- 11.2 and 85.3 +/- 20.0, respectively. The VAS-diabetes and CMG-diabetes scales were moderately correlated (r = 0.22), as were the VAS-lipid and CMG-lipid (r = 0.26). The majority (69.0%) of subjects had consistent adherence classifications across the dichotomous versions of VAS-diabetes and CMG-diabetes (kappa = 0.13), while 73.1% of subjects had consistent classifications for the dichotomous VAS-lipid and CMG-lipid (kappa = 0.19). CONCLUSIONS: The VAS self-reports of adherence to medications had moderate concordance with estimates derived from drug benefit claims. Although the majority of subjects were consistently classified by the VAS and claims, the concordance may not be sufficient for direct comparisons of studies using VAS data with studies using claims-based estimates.


Assuntos
Tratamento Farmacológico/estatística & dados numéricos , Revisão de Uso de Medicamentos/métodos , Revisão da Utilização de Seguros , Cooperação do Paciente/estatística & dados numéricos , Anticolesterolemiantes/uso terapêutico , Coleta de Dados/métodos , Prescrições de Medicamentos , Feminino , Sistemas Pré-Pagos de Saúde , Humanos , Hipoglicemiantes/uso terapêutico , Masculino , Michigan , Pessoa de Meia-Idade , Inquéritos e Questionários
20.
J Manag Care Pharm ; 13(2): 135-41, 2007 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-17330974

RESUMO

BACKGROUND: Utilization management tools (e.g., multitier copayment designs, prior authorization, step therapy, quantity limits) are commonly used to optimize the efficiency and appropriateness of drug therapy. However, these tools may also lead to unfavorable humanistic outcomes, including confusion or annoyance for patients. There is also some concern about whether these tools, along with the cost-sharing burden for medications, may cause patients to discontinue using their medications as well as lead to dissatisfaction with pharmacy benefits. Although anecdotal evidence can be collected from customer complaints, few studies have systematically examined the extent to which prescription drug plan enrollees experience difficulties in obtaining medications and whether these difficulties are associated with their satisfaction with the drug plan. OBJECTIVES: To determine from a member satisfaction survey (1) perception of difficulties experienced by drug plan members when they tried to obtain prescription medications, (2) whether some segments of members experienced more difficulties, and (3) whether self-reported difficulties in acquiring medications were associated with member satisfaction. METHODS: The analyses were based on a cross-sectional survey using a stratified sample of drug plan members. Four thousand employees or retirees who used the University of Michigan prescription drug plan were sent a survey in 2005 to ascertain their satisfaction with the drug plan as well as their experiences with the plan. Specifically, the analyses focused on how frequently the patients experienced difficulties in obtaining medications because of costs or drug use management interventions (e.g., prior authorization, step therapy). Logistic regression analyses examined the relationship of copayment changes and drug use management interventions on patients' satisfaction with the drug plan. RESULTS: Surveys were returned by 2,061 of the potential 3,667 eligible subjects with valid addresses (56.2% response rate). An overwhelming majority (83.7%) of respondents were satisfied with the pharmacy benefit- 17.6% reported being somewhat satisfied, 46.5% were satisfied, and 19.6% were very satisfied. Approximately 25% of drug plan members reported at least 1 difficulty in obtaining medication during the preceding year, including 11.4% who reported difficulties related to prior authorization or step therapy; only 2.0% reported that they couldn't afford their medication, and only 1.3% reported difficulty in paying the combined cost of their medications. Current employees were more likely to report difficulties than were retirees (30.7% vs. 19.1%; chi-square = 34.8; P <0.01), and users of the mail-service pharmacy were somewhat more likely to experience difficulties than users of community pharmacies (29.1% vs. 22.9%; chi-square = 9.92; P <0.01). The logistic regression analyses revealed that having difficulty obtaining medications (odds ratio [OR] = 0.27; 95% confidence interval [CI], 0.20-0.35) and experiencing a copayment increase (OR = 0.62; 95% CI, 0.48-0.81) were associated with a lower odds of member satisfaction. However, a high percentage of members were satisfied despite any difficulties or copayment changes: 66.9% for self-reported difficulty in obtaining medications compared with 89.7% (chi-square = 145.4, P <0.01) and 78.6% for self-reported copayment increase compared with 87.9% (chi-square = 30.2, P <0.01). CONCLUSION: Survey respondents were highly satisfied with their pharmacy benefits despite drug use management interventions in this pharmacy benefit plan. Respondents who reported a copayment increase or difficulty in obtaining medication were less likely to be satisfied with the drug plan.


Assuntos
Comportamento do Consumidor , Custo Compartilhado de Seguro , Custos de Medicamentos , Seguro de Serviços Farmacêuticos , Estudos Transversais , Planos de Assistência de Saúde para Empregados , Acessibilidade aos Serviços de Saúde , Humanos , Michigan , Universidades
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