Detalhe da pesquisa
1.
Synergistic binding of actinomycin D and echinomycin to DNA mismatch sites and their combined anti-tumour effects.
Nucleic Acids Res
; 51(8): 3540-3555, 2023 05 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36919604
2.
Staggered intercalation of DNA duplexes with base-pair modulation by two distinct drug molecules induces asymmetric backbone twisting and structure polymorphism.
Nucleic Acids Res
; 50(15): 8867-8881, 2022 08 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-35871296
3.
On Water Arrangements in Right- and Left-Handed DNA Structures.
Molecules
; 29(2)2024 Jan 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-38276583
4.
QN-302 demonstrates opposing effects between i-motif and G-quadruplex DNA structures in the promoter of the S100P gene.
Org Biomol Chem
; 22(1): 55-58, 2023 12 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-37970888
5.
Water spines and networks in G-quadruplex structures.
Nucleic Acids Res
; 49(1): 519-528, 2021 01 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33290519
6.
Targeting the ALS/FTD-associated A-DNA kink with anthracene-based metal complex causes DNA backbone straightening and groove contraction.
Nucleic Acids Res
; 49(16): 9526-9538, 2021 09 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-33836081
7.
The Potent G-Quadruplex-Binding Compound QN-302 Downregulates S100P Gene Expression in Cells and in an In Vivo Model of Pancreatic Cancer.
Molecules
; 28(6)2023 Mar 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36985425
8.
Machine learning shows torsion angle preferences in left-handed and right-handed quadruplex DNAs.
Biophys J
; 121(24): 4874-4881, 2022 12 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-35999813
9.
Beyond the double helix: DNA structural diversity and the PDB.
J Biol Chem
; 296: 100553, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33744292
10.
Polymorphic G:G mismatches act as hotspots for inducing right-handed Z DNA by DNA intercalation.
Nucleic Acids Res
; 47(16): 8899-8912, 2019 09 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-31361900
11.
A G-Quadruplex-Binding Small Molecule and the HDAC Inhibitor SAHA (Vorinostat) Act Synergistically in Gemcitabine-Sensitive and Resistant Pancreatic Cancer Cells.
Molecules
; 25(22)2020 Nov 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-33227941
12.
A naphthalene diimide G-quadruplex ligand inhibits cell growth and down-regulates BCL-2 expression in an imatinib-resistant gastrointestinal cancer cell line.
Bioorg Med Chem
; 26(11): 2958-2964, 2018 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29724653
13.
Folding of guanine quadruplex molecules-funnel-like mechanism or kinetic partitioning? An overview from MD simulation studies.
Biochim Biophys Acta Gen Subj
; 1861(5 Pt B): 1246-1263, 2017 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-27979677
14.
Flexibility and structural conservation in a c-KIT G-quadruplex.
Nucleic Acids Res
; 43(1): 629-44, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25452341
15.
Loop flexibility in human telomeric quadruplex small-molecule complexes.
Nucleic Acids Res
; 43(10): 4785-99, 2015 May 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-25940631
16.
Extended molecular dynamics of a c-kit promoter quadruplex.
Nucleic Acids Res
; 43(18): 8673-93, 2015 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26245347
17.
Induced-Fit Recognition of CCG Trinucleotide Repeats by a Nickel-Chromomycin Complex Resulting in Large-Scale DNA Deformation.
Angew Chem Int Ed Engl
; 56(30): 8761-8765, 2017 07 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-28544401
18.
Structural Insights into the Quadruplex-Duplex 3' Interface Formed from a Telomeric Repeat: A Potential Molecular Target.
J Am Chem Soc
; 138(4): 1226-33, 2016 Feb 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-26730610
19.
Atomic Force Microscopy and Voltammetric Investigation of Quadruplex Formation between a Triazole-Acridine Conjugate and Guanine-Containing Repeat DNA Sequences.
Anal Chem
; 87(12): 6141-9, 2015 Jun 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-25961908
20.
Comment on "Dark Nudges and Sludge in Big Alcohol: Behavioral Economics, Cognitive Biases, and Alcohol Industry Corporate Social Responsibility".
Milbank Q
; 98(4): E1-E4, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33377287