Detalhe da pesquisa
1.
Small molecule tractable PARP inhibitors: Scaffold construction approaches, mechanistic insights and structure activity relationship.
Bioorg Chem
; 141: 106893, 2023 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37783100
2.
Flavone-based dual PARP-Tubulin inhibitor manifesting efficacy against endometrial cancer.
J Enzyme Inhib Med Chem
; 38(1): 2276665, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37919954
3.
Beyond the vaccines: a glance at the small molecule and peptide-based anti-COVID19 arsenal.
J Biomed Sci
; 29(1): 65, 2022 Sep 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36064696
4.
Recent developments in epigenetic cancer therapeutics: clinical advancement and emerging trends.
J Biomed Sci
; 28(1): 27, 2021 Apr 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33840388
5.
The HDAC/HSP90 Inhibitor G570 Attenuated Blue Light-Induced Cell Migration in RPE Cells and Neovascularization in Mice through Decreased VEGF Production.
Molecules
; 26(14)2021 Jul 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-34299636
6.
Steering the antitumor drug discovery campaign towards structurally diverse indolines.
Bioorg Chem
; 94: 103436, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31761410
7.
Amide-tethered quinoline-resorcinol conjugates as a new class of HSP90 inhibitors suppressing the growth of prostate cancer cells.
Bioorg Chem
; 91: 103119, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31349117
8.
Correction: 2-Aroylquinoline-5,8-diones as potent anticancer agents displaying tubulin and heat shock protein 90 (HSP90) inhibition.
Org Biomol Chem
; 16(25): 4734, 2018 07 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29904758
9.
Triazole tethered isatin-coumarin based molecular hybrids as novel antitubulin agents: Design, synthesis, biological investigation and docking studies.
Bioorg Med Chem Lett
; 27(17): 3974-3979, 2017 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28797799
10.
Benzoflavones as cholesterol esterase inhibitors: Synthesis, biological evaluation and docking studies.
Bioorg Med Chem Lett
; 27(4): 850-854, 2017 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28117203
11.
2-Aroylquinoline-5,8-diones as potent anticancer agents displaying tubulin and heat shock protein 90 (HSP90) inhibition.
Org Biomol Chem
; 14(2): 716-723, 2016 Jan 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-26694589
12.
Microwave assisted synthesis of naphthopyrans catalysed by silica supported fluoroboric acid as a new class of non purine xanthine oxidase inhibitors.
Bioorg Med Chem Lett
; 24(2): 495-500, 2014 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24388807
13.
Synthesis and evaluation of naphthoflavones as a new class of non purine xanthine oxidase inhibitors.
Bioorg Med Chem Lett
; 24(17): 4192-7, 2014 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25106887
14.
Design, synthesis and evaluation of 2,4-diarylpyrano[3,2-c]chromen-5(4H)-one as a new class of non-purine xanthine oxidase inhibitors.
J Enzyme Inhib Med Chem
; : 1-7, 2014 Sep 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-25268805
15.
4,6-Diaryl/heteroarylpyrimidin-2(1H)-ones as a new class of xanthine oxidase inhibitors.
Arch Pharm (Weinheim)
; 347(7): 486-95, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24782427
16.
Recent advances and future directions on small molecule VEGFR inhibitors in oncological conditions.
Eur J Med Chem
; 272: 116472, 2024 Jun 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38728867
17.
Leveraging a rationally designed veliparib-based anilide eliciting anti-leukemic effects for the design of pH-responsive polymer nanoformulation.
Eur J Med Chem
; 273: 116507, 2024 Jul 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38776806
18.
First-in-Class Dual EZH2-HSP90 Inhibitor Eliciting Striking Antiglioblastoma Activity In Vitro and In Vivo.
J Med Chem
; 67(4): 2963-2985, 2024 Feb 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38285511
19.
Dual inhibition of CYP17A1 and HDAC6 by abiraterone-installed hydroxamic acid overcomes temozolomide resistance in glioblastoma through inducing DNA damage and oxidative stress.
Cancer Lett
; 586: 216666, 2024 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38311053
20.
Possible involvement of PPAR-γ in the anticonvulsant effect of Aegle marmelos (L.) Correa.
Neurochem Res
; 38(8): 1624-31, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23645163