[Myocarditis following mRNA vaccine]. / Myokarditis nach mRNA-Impfung.

This article presents the case of a 15-year-old adolescent presenting with myocarditis 4 days after receiving the 2nd dose of BNT162b2 mRNA vaccine (Comirnaty®) with no other identifiable cause. The main clinical symptom at presentation was chest pain. We found an elevated level of Troponin­I with preserved left ventricular systolic function. The cardiac MRI showed a clear pathologic result. With symptomatic therapy and strict bed rest, the symptoms resolved quickly and revealed a mild course.

Changes on magnetic resonance tomography in the knee joints of marathon runners: a 10-year longitudinal study.

OBJECTIVE: The aim of the study was to evaluate long-term damage in the internal structures of the knee joints of recreational long-distance runners. MATERIALS AND METHODS: Ten years after their participation in a baseline study concerning their knee joints, seven long-distance runners and one who had given up long-distance running were invited to participate in a repeat magnetic resonance imaging (MRI) investigation. The same evaluation criteria and the same technical equipment were used, and the results of the two investigations were compared. RESULT: No adverse long-term consequences were observed in six of the seven active runners, regardless of pre-existing damage at the baseline investigation. In one case the arthrotic changes were progressive in nature. The person who had given up running presented with severe deterioration of the internal structures of the knee joint. CONCLUSION: Non-physiological maximal loads secondary to the marathon race do not cause any permanent damage in the internal structures of the knee joint in individuals without significant pre-existing damage. A disposition for premature arthrosis was not registered in the population investigated. A protective value of long distance running on the internal structures of the knee joint is discussed.

Frequency and risk factors for meningioma in clinically healthy 75-year-old patients: results of the Transdanube Ageing Study (VITA).

BACKGROUND: The prevalence of clinically silent intracranial tumors in specific populations is poorly researched. It is known that, in advanced age groups, the number of clinically manifest meningiomas constitute a small proportion of the actual number of cases. The goals of the current study were to determine the frequency of asymptomatic patients with meningioma in advanced age and to identify risk factors for meningiomas in this population. METHODS: Between May 2000 and November 2002, 532 probands from a specifically defined geographic area of Vienna who were age 75 years underwent a magnetic resonance imaging scan of the brain and were evaluated for the presence of a space-occupying mass. All probands were examined clinically and neurologically as well as by a neuropsychiatrist. The patients' medical histories were carefully documented with regard to previous diseases, medication, and lifestyle, as were their laboratory reports. The collected data were correlated and similarities among subjects with meningioma were determined. RESULTS: Nine meningiomas that were unknown until the time of investigation were observed among the 318 women included in the trial (corresponding to a calculated prevalence of 2800/100,000 clinically silent meningiomas in 75-year-old women). No tumors were found among men. Associated clinical changes or deficits were not observed in any subject. Apart from advanced age and female gender, no other accepted or well known risk factors were observed in the tumor patients. CONCLUSIONS: Clinically quiescent meningiomas in the elderly female population were more common than was believed to be the case to date. Known and influenceable risk factors were found to be less important than age and gender. The high frequency of this lesion should be considered when deciding on the treatment of patients with incidentally discovered, clinically quiescent meningiomas.