Detalhe da pesquisa
1.
Comprehensive Fragment Screening of the SARS-CoV-2 Proteome Explores Novel Chemical Space for Drug Development.
Angew Chem Int Ed Engl
; 61(46): e202205858, 2022 11 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-36115062
2.
19 F NMR-Based Fragment Screening for 14 Different Biologically Active RNAs and 10 DNA and Protein Counter-Screens.
Chembiochem
; 22(2): 423-433, 2021 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32794266
3.
Exploring the Druggability of Conserved RNA Regulatory Elements in the SARS-CoV-2 Genome.
Angew Chem Int Ed Engl
; 60(35): 19191-19200, 2021 08 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-34161644
4.
The domain architecture of PtkA, the first tyrosine kinase from Mycobacterium tuberculosis, differs from the conventional kinase architecture.
J Biol Chem
; 293(30): 11823-11836, 2018 07 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-29884774
5.
Oxidation of the Mycobacterium tuberculosis key virulence factor protein tyrosine phosphatase A (MptpA) reduces its phosphatase activity.
FEBS Lett
; 596(12): 1503-1515, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35397176
6.
Structural characterization of the intrinsically disordered domain of Mycobacterium tuberculosis protein tyrosine kinase A.
FEBS Lett
; 592(7): 1233-1245, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29494752