Detalhe da pesquisa
1.
Tailored multivalent peptide targeting the B-subunit pentamer of cholera toxin inhibits its intestinal toxicity by inducing aberrant transport of the toxin in cells.
Biochem Biophys Res Commun
; 716: 149991, 2024 Jul 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38704888
2.
Development of a novel tetravalent peptide that absorbs subtilase cytotoxin by targeting the receptor-binding B-subunit.
Biochem Biophys Res Commun
; 629: 95-100, 2022 11 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36115284
3.
A tetravalent peptide that binds to the RANK-binding region of TRAF6 via a multivalent interaction efficiently inhibits osteoclast differentiation.
Biochem Biophys Res Commun
; 636(Pt 1): 178-183, 2022 12 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-36334442
4.
A nontoxigenic form of Shiga toxin 2 suppresses the production of amyloid ß by altering the intracellular transport of amyloid precursor protein through its receptor-binding B-subunit.
Biochem Biophys Res Commun
; 557: 247-253, 2021 06 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33894410
5.
Pleckstrin homology domain of p210 BCR-ABL interacts with cardiolipin to regulate its mitochondrial translocation and subsequent mitophagy.
Genes Cells
; 23(1): 22-34, 2018 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-29205725
6.
Synthetic construction of sugar-amino acid hybrid polymers involving globotriaose or lactose and evaluation of their biological activities against Shiga toxins produced by Escherichia coli O157:H7.
Bioorg Med Chem
; 26(22): 5792-5803, 2018 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30420327
7.
Acquired Resistance to Shiga Toxin-Induced Apoptosis by Loss of CD77 Expression in Human Myelogenous Leukemia Cell Line, THP-1.
Biol Pharm Bull
; 41(9): 1475-1479, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30175782
8.
M-COPA, a novel Golgi system disruptor, suppresses apoptosis induced by Shiga toxin.
Genes Cells
; 21(8): 901-6, 2016 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-27302278
9.
Affinity-Based Screening of Tetravalent Peptides Identifies Subtype-Selective Neutralizers of Shiga Toxin 2d, a Highly Virulent Subtype, by Targeting a Unique Amino Acid Involved in Its Receptor Recognition.
Infect Immun
; 84(9): 2653-61, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27382021
10.
JNK1/2-dependent phosphorylation of angulin-1/LSR is required for the exclusive localization of angulin-1/LSR and tricellulin at tricellular contacts in EpH4 epithelial sheet.
Genes Cells
; 19(7): 565-81, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24889144
11.
Identification of a wide range of motifs inhibitory to shiga toxin by affinity-driven screening of customized divalent peptides synthesized on a membrane.
Appl Environ Microbiol
; 81(3): 1092-100, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25452283
12.
Intracellular phosphatidylserine is essential for retrograde membrane traffic through endosomes.
Proc Natl Acad Sci U S A
; 108(38): 15846-51, 2011 Sep 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-21911378
13.
Identification of a peptide-based neutralizer that potently inhibits both Shiga toxins 1 and 2 by targeting specific receptor-binding regions.
Infect Immun
; 81(6): 2133-8, 2013 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-23545297
14.
Novel multivalent S100A8 inhibitory peptides attenuate tumor progression and metastasis by inhibiting the TLR4-dependent pathway.
Cancer Gene Ther
; 30(7): 973-984, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36932197
15.
A tailored tetravalent peptide displays dual functions to inhibit amyloid ß production and aggregation.
Commun Biol
; 6(1): 383, 2023 04 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37031306
16.
Hepatitis B Virus Utilizes a Retrograde Trafficking Route via the Trans-Golgi Network to Avoid Lysosomal Degradation.
Cell Mol Gastroenterol Hepatol
; 15(3): 533-558, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36270602
17.
A unique peptide-based pharmacophore identifies an inhibitory compound against the A-subunit of Shiga toxin.
Sci Rep
; 12(1): 11443, 2022 07 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35794188
18.
Transmembrane BAX inhibitor motif containing (TMBIM) family proteins perturbs a trans-Golgi network enzyme, Gb3 synthase, and reduces Gb3 biosynthesis.
J Biol Chem
; 285(46): 35505-18, 2010 Nov 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-20837469
19.
Rescue from lethal Shiga toxin 2-induced renal failure with a cell-permeable peptide.
Pediatr Nephrol
; 26(11): 2031-9, 2011 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-21603905
20.
Identification of a peptide motif that potently inhibits two functionally distinct subunits of Shiga toxin.
Commun Biol
; 4(1): 538, 2021 05 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33972673