Detalhe da pesquisa
1.
Metastatic recurrence in colorectal cancer arises from residual EMP1+ cells.
Nature
; 611(7936): 603-613, 2022 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-36352230
2.
NEDD4 and NEDD4L regulate Wnt signalling and intestinal stem cell priming by degrading LGR5 receptor.
EMBO J
; 39(3): e102771, 2020 02 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31867777
3.
The Transcription Co-Repressors MTG8 and MTG16 Regulate Exit of Intestinal Stem Cells From Their Niche and Differentiation Into Enterocyte vs Secretory Lineages.
Gastroenterology
; 159(4): 1328-1341.e3, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32553763
4.
A brief history of organoids.
Am J Physiol Cell Physiol
; 319(1): C151-C165, 2020 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32459504
5.
Targeting Wnt signaling in colorectal cancer. A Review in the Theme: Cell Signaling: Proteins, Pathways and Mechanisms.
Am J Physiol Cell Physiol
; 309(8): C511-21, 2015 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26289750
6.
Mitochondrial phosphoenolpyruvate carboxykinase (PEPCK-M) is a pro-survival, endoplasmic reticulum (ER) stress response gene involved in tumor cell adaptation to nutrient availability.
J Biol Chem
; 289(32): 22090-102, 2014 Aug 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-24973213
7.
Akt-dependent activation of the heart 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFKFB2) isoenzyme by amino acids.
J Biol Chem
; 288(15): 10640-51, 2013 Apr 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-23457334
8.
PFKFB3 activation in cancer cells by the p38/MK2 pathway in response to stress stimuli.
Biochem J
; 452(3): 531-43, 2013 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23548149
9.
Cachd1 interacts with Wnt receptors and regulates neuronal asymmetry in the zebrafish brain.
Science
; 384(6695): 573-579, 2024 May 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38696577
10.
Progestins activate 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3) in breast cancer cells.
Biochem J
; 442(2): 345-56, 2012 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22115192
11.
USP7 inactivation suppresses APC-mutant intestinal hyperproliferation and tumor development.
Stem Cell Reports
; 18(2): 570-584, 2023 02 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-36669491
12.
Cooperation of adenosine with macrophage Toll-4 receptor agonists leads to increased glycolytic flux through the enhanced expression of PFKFB3 gene.
J Biol Chem
; 286(22): 19247-58, 2011 Jun 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-21464136
13.
Mex3a marks drug-tolerant persister colorectal cancer cells that mediate relapse after chemotherapy.
Nat Cancer
; 3(9): 1052-1070, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35773527
14.
Atypical cyclin P regulates cancer cell stemness through activation of the WNT pathway.
Cell Oncol (Dordr)
; 44(6): 1273-1286, 2021 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-34604945
15.
Serine synthesis pathway inhibition cooperates with dietary serine and glycine limitation for cancer therapy.
Nat Commun
; 12(1): 366, 2021 01 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-33446657
16.
Identifying strategies to target the metabolic flexibility of tumours.
Nat Metab
; 2(4): 335-350, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32694609
17.
Engineering transplantable jejunal mucosal grafts using patient-derived organoids from children with intestinal failure.
Nat Med
; 26(10): 1593-1601, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32895569
18.
SH3BP4 Regulates Intestinal Stem Cells and Tumorigenesis by Modulating ß-Catenin Nuclear Localization.
Cell Rep
; 26(9): 2266-2273.e4, 2019 02 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-30811977
19.
Role of Akt/PKB and PFKFB isoenzymes in the control of glycolysis, cell proliferation and protein synthesis in mitogen-stimulated thymocytes.
Cell Signal
; 34: 23-37, 2017 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28235572
20.
USP7 Is a Tumor-Specific WNT Activator for APC-Mutated Colorectal Cancer by Mediating ß-Catenin Deubiquitination.
Cell Rep
; 21(3): 612-627, 2017 Oct 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-29045831