Detalhe da pesquisa
1.
Synthesis of a novel glibenclamide-pioglitazone hybrid compound and its effects on glucose homeostasis in normal and insulin-resistant rats.
Bioorg Chem
; 114: 105157, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34328855
2.
Synthesis of chalcones derived from 1-naphthylacetophenone and evaluation of their cytotoxic and apoptotic effects in acute leukemia cell lines.
Bioorg Chem
; 116: 105315, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34496319
3.
Cell Cycle Arrest and Apoptosis Induction by a New 2,4-Dinitrobenzenesulfonamide Derivative In Acute Leukemia Cells.
J Pharm Pharm Sci
; 24: 23-36, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33735604
4.
Sulfonyl(thio)urea derivative induction of insulin secretion is mediated by potassium, calcium, and sodium channel signal transduction.
J Cell Physiol
; 234(7): 10138-10147, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30417369
5.
Synthesis of novel pyrazoline derivatives and the evaluation of death mechanisms involved in their antileukemic activity.
Bioorg Med Chem
; 27(2): 375-382, 2019 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30579801
6.
Synthetic thiosemicarbazones as a new class of Mycobacterium tuberculosis protein tyrosine phosphatase A inhibitors.
Bioorg Med Chem
; 26(21): 5742-5750, 2018 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30389409
7.
Effects of 1,3,5-triphenyl-4,5-dihydro-1H-pyrazole derivatives on cell-cycle and apoptosis in human acute leukemia cell lines.
Can J Physiol Pharmacol
; 95(5): 548-563, 2017 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-28177693
8.
Incretinomimetic and Insulinomimetic Effect of (2E)-N'-(1'-Naphthyl)-3,4,5-Trimethoxybenzohydrazide for Glycemic Homeostasis.
J Cell Biochem
; 117(5): 1199-209, 2016 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-26447772
9.
Investigation of cellular mechanisms involved in apoptosis induced by a synthetic naphthylchalcone in acute leukemia cell lines.
Anticancer Drugs
; 27(8): 738-47, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27337110
10.
Synthetic compounds from an in house library as inhibitors of falcipain-2 from Plasmodium falciparum.
J Enzyme Inhib Med Chem
; 30(2): 299-307, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24964346
11.
Antiherpetic mechanism of a sulfated derivative of Agaricus brasiliensis fruiting bodies polysaccharide.
Intervirology
; 57(6): 375-83, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25359160
12.
Apoptotic events induced by maleimides on human acute leukemia cell lines.
Chem Res Toxicol
; 26(12): 1904-16, 2013 Dec 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-24304350
13.
Activity of chalcones derived from 2,4,5-trimethoxybenzaldehyde against Meloidogyne exigua and in silico interaction of one chalcone with a putative caffeic acid 3-O-methyltransferase from Meloidogyne incognita.
Exp Parasitol
; 135(4): 661-8, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24140596
14.
Antimalarial activity of 4-metoxychalcones: docking studies as falcipain/plasmepsin inhibitors, ADMET and lipophilic efficiency analysis to identify a putative oral lead candidate.
Molecules
; 18(12): 15276-87, 2013 Dec 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-24335577
15.
Antimetastatic activity and low systemic toxicity of tetradecyl gallate in a preclinical melanoma mouse model.
Invest New Drugs
; 30(3): 870-9, 2012 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-21221709
16.
Evaluation of apoptotic effect of cyclic imide derivatives on murine B16F10 melanoma cells.
Bioorg Med Chem
; 19(21): 6285-91, 2011 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21964182
17.
Synthesis and antidepressant-like activity evaluation of sulphonamides and sulphonyl-hydrazones.
Bioorg Med Chem
; 19(14): 4295-306, 2011 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21696965
18.
Trimethoxy-chalcone derivatives inhibit growth of Leishmania braziliensis: synthesis, biological evaluation, molecular modeling and structure-activity relationship (SAR).
Bioorg Med Chem
; 19(16): 5046-52, 2011 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21757358
19.
Molecular events and cytotoxic effects of a novel thiosemicarbazone derivative in human leukemia and lymphoma cell lines.
Hematol Oncol Stem Cell Ther
; 14(1): 51-64, 2021 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-32763229
20.
Naphthylchalcones induce apoptosis and caspase activation in a leukemia cell line: The relationship between mitochondrial damage, oxidative stress, and cell death.
Bioorg Med Chem
; 18(22): 8026-34, 2010 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20952199