Detalhe da pesquisa
1.
Polygenic architecture of rare coding variation across 394,783 exomes.
Nature
; 614(7948): 492-499, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36755099
2.
Partitioning gene-mediated disease heritability without eQTLs.
Am J Hum Genet
; 109(3): 405-416, 2022 03 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35143757
3.
HAPNEST: efficient, large-scale generation and evaluation of synthetic datasets for genotypes and phenotypes.
Bioinformatics
; 39(9)2023 09 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37647640
4.
Extreme Polygenicity of Complex Traits Is Explained by Negative Selection.
Am J Hum Genet
; 105(3): 456-476, 2019 09 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31402091
5.
Shared genetic and experimental links between obesity-related traits and asthma subtypes in UK Biobank.
J Allergy Clin Immunol
; 145(2): 537-549, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31669095
6.
Extremely sparse models of linkage disequilibrium in ancestrally diverse association studies.
Nat Genet
; 55(9): 1494-1502, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37640881
7.
Combining SNP-to-gene linking strategies to identify disease genes and assess disease omnigenicity.
Nat Genet
; 54(6): 827-836, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35668300
8.
Statistical and functional convergence of common and rare genetic influences on autism at chromosome 16p.
Nat Genet
; 54(11): 1630-1639, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36280734
9.
The distribution of common-variant effect sizes.
Nat Genet
; 53(8): 1243-1249, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34326547
10.
Quantifying genetic effects on disease mediated by assayed gene expression levels.
Nat Genet
; 52(6): 626-633, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32424349
11.
Quantification of frequency-dependent genetic architectures in 25 UK Biobank traits reveals action of negative selection.
Nat Commun
; 10(1): 790, 2019 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30770844
12.
Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels.
Nat Genet
; 51(10): 1459-1474, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31578528
13.
Author Correction: Distinguishing genetic correlation from causation across 52 diseases and complex traits.
Nat Genet
; 50(12): 1753, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30401984
14.
Distinguishing genetic correlation from causation across 52 diseases and complex traits.
Nat Genet
; 50(12): 1728-1734, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30374074