Detalhe da pesquisa
1.
FOXO1 represses PPARα-Mediated induction of FGF21 gene expression.
Biochem Biophys Res Commun
; 644: 122-129, 2023 02 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36640666
2.
Elamipretide treatment during pregnancy ameliorates the progression of polycystic kidney disease in maternal and neonatal mice with PKD1 mutations.
Kidney Int
; 101(5): 906-911, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34953771
3.
Functional resilience of C57BL/6J mouse heart to dietary fat overload.
Am J Physiol Heart Circ Physiol
; 321(5): H850-H864, 2021 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34477461
4.
Glucose transporter 4-deficient hearts develop maladaptive hypertrophy in response to physiological or pathological stresses.
Am J Physiol Heart Circ Physiol
; 313(6): H1098-H1108, 2017 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28822962
5.
Spiropiperidine Sultam and Lactam Templates: Diastereoselective Overman Rearrangement and Metathesis followed by NH Arylation.
J Org Chem
; 82(23): 12246-12256, 2017 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29096057
6.
Non-metastatic squamous cell carcinoma within a Rathke's cleft cyst.
Pituitary
; 19(1): 105-9, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25715776
7.
An Improved System for the Aqueous Lipshutz-Negishi Cross-Coupling of Alkyl Halides with Aryl Electrophiles.
Angew Chem Int Ed Engl
; 55(5): 1849-53, 2016 Jan 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-26676401
8.
Engaging nonaromatic, heterocyclic tosylates in reductive cross-coupling with aryl and heteroaryl bromides.
J Org Chem
; 80(5): 2907-11, 2015 Mar 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-25711834
9.
Synthesis of Small 3-Fluoro- and 3,3-Difluoropyrrolidines Using Azomethine Ylide Chemistry.
J Org Chem
; 80(14): 7266-74, 2015 Jul 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-26057617
10.
Reductive cross-coupling of nonaromatic, heterocyclic bromides with aryl and heteroaryl bromides.
J Org Chem
; 79(12): 5771-80, 2014 Jun 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-24892751
11.
Stereoselective synthesis of spiropiperidines as BACE-1 aspartyl protease inhibitors via late stage N-arylation of a 1,8-diazaspiro[4.5]dec-3-en-2-one pharmacophore.
J Org Chem
; 78(6): 2661-9, 2013 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23438191
12.
Cerebrospinal fluid ß-Amyloid turnover in the mouse, dog, monkey and human evaluated by systematic quantitative analyses.
Neurodegener Dis
; 12(1): 36-50, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-22922480
13.
Loss of FoxOs in muscle increases strength and mitochondrial function during aging.
J Cachexia Sarcopenia Muscle
; 14(1): 243-259, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36442857
14.
A conserved role for phosphatidylinositol 3-kinase but not Akt signaling in mitochondrial adaptations that accompany physiological cardiac hypertrophy.
Cell Metab
; 6(4): 294-306, 2007 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-17908558
15.
Cerebrospinal fluid amyloid-ß (Aß) as an effect biomarker for brain Aß lowering verified by quantitative preclinical analyses.
J Pharmacol Exp Ther
; 342(2): 366-75, 2012 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-22562771
16.
α4ß2 nicotinic acetylcholine receptor partial agonists with low intrinsic efficacy have antidepressant-like properties.
Behav Pharmacol
; 22(4): 291-9, 2011 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-21566524
17.
Immediate preoperative hyperglycemia correlates with complications in non-cardiac surgical cases.
J Clin Anesth
; 74: 110375, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34147016
18.
Transcriptomic Regulation of Muscle Mitochondria and Calcium Signaling by Insulin/IGF-1 Receptors Depends on FoxO Transcription Factors.
Front Physiol
; 12: 779121, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-35185597
19.
Differential roles of FOXO transcription factors on insulin action in brown and white adipose tissue.
J Clin Invest
; 131(19)2021 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34428182
20.
Peripheral Insulin Regulates a Broad Network of Gene Expression in Hypothalamus, Hippocampus, and Nucleus Accumbens.
Diabetes
; 70(8): 1857-1873, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34031123