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1.
Med J Aust ; 207(5): 195-200, 2017 Aug 04.
Artigo em Inglês | MEDLINE | ID: mdl-28987132

RESUMO

OBJECTIVE: To examine the safety and efficacy of the Improved Assessment of Chest pain Trial (IMPACT) protocol, a strategy for accelerated assessment of patients presenting to emergency departments (EDs) with chest pain. DESIGN, SETTING AND PARTICIPANTS: IMPACT was an intervention trial at a single tertiary referral hospital (Royal Brisbane and Women's Hospital) during February 2011 - March 2014. 1366 prospectively recruited patients presenting to the ED with symptoms of suspected acute coronary syndrome (ACS) were stratified into groups at low, intermediate or high risk of an ACS. INTERVENTION: High risk patients were treated according to NHFA/CSANZ guidelines. Low and intermediate risk patients underwent troponin testing (sensitive assay) 0 and 2 hours after presentation. Intermediate risk patients underwent objective testing after the second troponin test; low risk patients were discharged without further objective testing. MAIN OUTCOME MEASURES: The primary outcome was an ACS within 30 days of presentation. Secondary outcomes were ED and hospital lengths of stay (LOS). RESULTS: The IMPACT protocol stratified 244 (17.9%) patients to low risk, 789 (57.7%) to intermediate risk, and 333 (24.4%) to high risk categories. The overall 30-day ACS rate was 6.6%, but there were no ACS events in the low risk group, and 14 (1.8%) in the intermediate risk group. The median hospital LOS was 5.1 hours (IQR, 4.2-5.6 h) for low risk and 7.7 hours (IQR, 6.1-21 h) for intermediate risk patients. CONCLUSIONS: The IMPACT protocol safely and efficiently allowed a large proportion of patients presenting to EDs with chest pain to undergo accelerated assessment for risk of an ACS. CLINICAL TRIAL REGISTRATION: Australian New Zealand Clinical Trials Registry ACTRN12611000206921.


Assuntos
Síndrome Coronariana Aguda/diagnóstico , Dor no Peito/diagnóstico , Ensaios Clínicos Controlados não Aleatórios como Assunto/métodos , Medição da Dor/métodos , Adulto , Serviço Hospitalar de Emergência , Feminino , Humanos , Tempo de Internação/estatística & dados numéricos , Masculino , Pessoa de Meia-Idade , Infarto do Miocárdio/diagnóstico , Nova Zelândia , Alta do Paciente/estatística & dados numéricos , Estudos Prospectivos , Medição de Risco , Centros de Atenção Terciária , Resultado do Tratamento , Troponina/análise
2.
Cancer ; 121(17): 3018-26, 2015 Sep 01.
Artigo em Inglês | MEDLINE | ID: mdl-25946658

RESUMO

BACKGROUND: There are significant disparities in cancer outcomes between Indigenous and non-Indigenous Australians. Identifying the unmet supportive care needs of Indigenous Australians with cancer is imperative to improve their cancer care. The purpose of the current study was to test the psychometric properties of a supportive cancer care needs assessment tool for Indigenous people (SCNAT-IP) with cancer. METHODS: The SCNAT-IP was administered to 248 Indigenous Australians diagnosed with a range of cancer types and stages, and who received treatment in 1 of 4 Queensland hospitals. All 39 items were assessed for ceiling and floor effects and were analyzed using exploratory factor analysis to determine construct validity. Identified factors were assessed for internal consistency and convergent validity to validated psychosocial tools. RESULTS: Exploratory factor analysis revealed a 4-factor structure (physical and psychological, hospital care, information and communication, and practical and cultural needs) explaining 51% of the variance. Internal consistency of the 4 subscales was good, with Cronbach alpha reliability coefficients ranging from .70 to .89. Convergent validity was supported by significant correlations between the SCNAT-IP with the National Comprehensive Cancer Network Distress Thermometer (correlation coefficient [r] = 0.60; P<.001) and the Cancer Worry Chart (r = 0.58; P<.001) and a moderately strong negative correlation with the Assessment of Quality of Life questionnaire (r = -0.56; P<.001). CONCLUSIONS: These data provide initial support for the SCNAT-IP, a measure of multiple supportive care needs domains specific to Indigenous Australian patients with cancer undergoing treatment.


Assuntos
Neoplasias/terapia , Adulto , Austrália , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Havaiano Nativo ou Outro Ilhéu do Pacífico , Avaliação das Necessidades , Psicometria , Qualidade de Vida , Apoio Social , Adulto Jovem
3.
Thorax ; 69(8): 740-5, 2014 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-24743559

RESUMO

BACKGROUND: Person-to-person transmission of respiratory pathogens, including Pseudomonas aeruginosa, is a challenge facing many cystic fibrosis (CF) centres. Viable P aeruginosa are contained in aerosols produced during coughing, raising the possibility of airborne transmission. METHODS: Using purpose-built equipment, we measured viable P aeruginosa in cough aerosols at 1, 2 and 4 m from the subject (distance) and after allowing aerosols to age for 5, 15 and 45 min in a slowly rotating drum to minimise gravitational settling and inertial impaction (duration). Aerosol particles were captured and sized employing an Anderson Impactor and cultured using conventional microbiology. Sputum was also cultured and lung function and respiratory muscle strength measured. RESULTS: Nineteen patients with CF, mean age 25.8 (SD 9.2) years, chronically infected with P aeruginosa, and 10 healthy controls, 26.5 (8.7) years, participated. Viable P aeruginosa were detected in cough aerosols from all patients with CF, but not from controls; travelling 4 m in 17/18 (94%) and persisting for 45 min in 14/18 (78%) of the CF group. Marked inter-subject heterogeneity of P aeruginosa aerosol colony counts was seen and correlated strongly (r=0.73-0.90) with sputum bacterial loads. Modelling decay of viable P aeruginosa in a clinic room suggested that at the recommended ventilation rate of two air changes per hour almost 50 min were required for 90% to be removed after an infected patient left the room. CONCLUSIONS: Viable P aeruginosa in cough aerosols travel further and last longer than recognised previously, providing additional evidence of airborne transmission between patients with CF.


Assuntos
Tosse/microbiologia , Fibrose Cística/microbiologia , Infecções por Pseudomonas/microbiologia , Infecções por Pseudomonas/transmissão , Pseudomonas aeruginosa/isolamento & purificação , Adolescente , Adulto , Aerossóis , Estudos de Casos e Controles , Feminino , Humanos , Exposição por Inalação , Masculino , Testes de Função Respiratória , Escarro/microbiologia
4.
Med J Aust ; 198(8): 431-4, 2013 May 06.
Artigo em Inglês | MEDLINE | ID: mdl-23641994

RESUMO

OBJECTIVE: To assess the current frequency of sunburn, a preventable risk factor for skin cancer, among Queensland adults. DESIGN AND SETTING: Cross-sectional population-based surveys of 16 473 residents aged ≥ 18 2013s across Queensland in 2009 and 2010. MAIN OUTCOME MEASURES: Proportion of the adult population reporting sunburn (skin reddening lasting 12 hours or more) during the previous weekend, by age, sex and other risk factors. RESULTS: One in eight men and one in 12 women in Queensland reported being sunburnt on the previous weekend. Age up to 65 2013s was the strongest predictor of sunburn: eg, people aged 18-24 2013s were seven times more likely (adjusted odds ratio [OR], 7.35; 95% CI, 5.09-10.62) and those aged 35-44 2013s were five times more likely (adjusted OR, 5.22) to report sunburn compared with those aged ≥ 65 2013s. Not having a tertiary education and being in the workforce were also significantly associated with sunburn. Those who had undertaken any physical activity the previous week were more likely to be sunburnt than those who were physically inactive. Sunburn was significantly less likely among people who generally took sun-protective measures in summer. Sunburn was not related to location of residence, socioeconomic disadvantage, skin colour, body weight or current smoking status. CONCLUSIONS: Sunburn remains a public health problem among Queensland residents, especially those under 45 2013s of age. Sun-safe habits reduce sunburn risk, but advice must be integrated with health promotion messages regarding physical activity to reduce the skin cancer burden while maintaining active wellbeing.


Assuntos
Queimadura Solar/epidemiologia , Adolescente , Adulto , Distribuição por Idade , Idoso , Austrália/epidemiologia , Estudos Transversais , Escolaridade , Emprego , Feminino , Inquéritos Epidemiológicos , Humanos , Masculino , Pessoa de Meia-Idade , Atividade Motora , Roupa de Proteção , Distribuição por Sexo , Queimadura Solar/prevenção & controle , Protetores Solares/administração & dosagem , Adulto Jovem
5.
Clin Chem ; 58(1): 274-83, 2012 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-22125306

RESUMO

BACKGROUND: Data to standardize and harmonize the differences between cardiac troponin assays are needed to support their universal status in diagnosis of myocardial infarction. We characterized the variation between methods, the comparability of the 99th-percentile cutoff thresholds, and the occurrence of outliers in 4 cardiac troponin assays. METHODS: Cardiac troponin was measured in duplicate in 2358 patient samples on 4 platforms: Abbott Architect i2000SR, Beckman Coulter Access2, Roche Cobas e601, and Siemens ADVIA Centaur XP. RESULTS: The observed total variances between the 3 cardiac troponin I (cTnI) methods and between the cTnI and cardiac troponin T (cTnT) methods were larger than expected from the analytical imprecision (3.0%-3.7%). The between-method variations of 26% between cTnI assays and 127% between cTnI and cTnT assays were the dominant contributors to total variances. The misclassification of results according to the 99th percentile was 3%-4% between cTnI assays and 15%-17% between cTnI and cTnT. The Roche cTnT assay identified 49% more samples as positive than the Abbott cTnI. Outliers between methods were detected in 1 patient (0.06%) with Abbott, 8 (0.45%) with Beckman Coulter, 10 (0.56%) with Roche, and 3 (0.17%) with Siemens. CONCLUSIONS: The universal definition of myocardial infarction should not depend on the choice of analyte or analyzer, and the between- and within-method differences described here need to be considered in the application of cardiac troponin in this respect. The variation between methods that cannot be explained by analytical imprecision and the discordant classification of results according to the respective 99th percentiles should be addressed.


Assuntos
Testes de Química Clínica/normas , Troponina I/sangue , Biomarcadores/sangue , Humanos , Controle de Qualidade
6.
Clin Chem ; 57(5): 710-8, 2011 May.
Artigo em Inglês | MEDLINE | ID: mdl-21372180

RESUMO

BACKGROUND: It is important that cardiac troponin be measured accurately with a robust method to limit false results with potentially adverse clinical outcomes. In this study, we characterized the robustness of 4 analytical platforms by measuring the outlier rate between duplicate results. METHODS: We measured cardiac troponin concurrently in duplicate with 4 analyzers on 2391 samples. The outliers were detected from the difference between duplicate results and by calculating a z value: z = (result 1 - result 2) ÷ √(SD1(est)² + SD2(est)²), with z > 3.48 identifying outliers with a probability of 0.0005. RESULTS: The outlier rates were as follows: Abbott Architect i2000SR STAT Troponin-I, 0.10% (0.01%-0.19%); Beckman Coulter Access2 Enhanced AccuTnI, 0.44% (0.25%-0.63%); Roche Cobas e601 TroponinT hs, 0.06% (0.00%-0.13%); and Siemens ADVIA Centaur XP TnI-Ultra, 0.10% (0.01%-0.19%). The occurrence of outliers was higher than statistically expected on all platforms except the Cobas e601 (χ² = 2.7; P = 0.10). A conservative approach with a constant 10% CV and z > 5.0 identified outliers with clear clinical impact and resulted in outlier rates of 0.11% (0.02%-0.20%) with the Architect i2000SR STAT Troponin-I, 0.36% (0.19%-0.53%) with the Access2 Enhanced AccuTnI, 0.02% (0.00%-0.06%) with the Cobas e601 TroponinT hs, and 0.06% (0.00%-0.13%) with the ADVIA Centaur XP TnI-Ultra. CONCLUSIONS: Outliers occurred on all analytical platforms, at different rates. Clinicians should be made aware by their laboratory colleagues of the existence of outliers and the rate at which they occur.


Assuntos
Troponina I/sangue , Troponina T/sangue , Biomarcadores/sangue , Interpretação Estatística de Dados , Reações Falso-Positivas , Humanos , Imunoensaio/métodos , Imunoensaio/normas , Miocárdio/metabolismo
7.
Aust N Z J Obstet Gynaecol ; 51(2): 109-13, 2011 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-21466510

RESUMO

BACKGROUND: National Health and Medical Research Council (NHMRC) guidelines published in 2005 changed the management of cervical squamous intraepithelial lesions. Asymptomatic low-grade abnormalities may be treated conservatively as many regress spontaneously. Cervical changes reflect infection with the human papilloma virus (HPV). Risk factors for acquiring HPV are the same as those for other sexually transmitted infections (STIs). AIMS: To perform a comparison of the Papanicolaou (PAP) smear, histology results of the cervical biopsy and large loop excision of transformation zone (LLETZ) to determine what proportion were over treated, and conversely what proportion would have been under treated in relation to the 2005 NHMRC guidelines. This group of patients was reviewed also for history of STI or concurrent infection. METHODS: Retrospective chart audit of LLETZ procedures and related histology in a population of women under 25 years between 1999 and 2003 presenting to a colposcopy clinic at a regional hospital. RESULTS: Two hundred and fifty-one asymptomatic women underwent LLETZ procedures. Of them, 27.6% reported a history of STI and 9.2% had a positive test result or history of Chlamydia. Based on the 2005 NHMRC guidelines, which require high-grade squamous intraepithelial lesions (HSIL) on PAP or biopsy, 34% of women had no indication for LLETZ. Of these, 65% were over treated having no HSIL on LLETZ histology and 35% would have been under treated. CONCLUSIONS: The 2005 NHMRC guidelines should result in 33.9% fewer LLETZ procedures being performed in the younger age group. This has benefits for their future fertility needs. STI screening would be beneficial in this group when seen at colposcopy clinics, as they have significant rates of prior or current infection.


Assuntos
Procedimentos Cirúrgicos em Ginecologia/métodos , Procedimentos Desnecessários , Displasia do Colo do Útero/cirurgia , Neoplasias do Colo do Útero/cirurgia , Biópsia , Feminino , Humanos , Teste de Papanicolaou , Guias de Prática Clínica como Assunto , Estudos Retrospectivos , Procedimentos Desnecessários/estatística & dados numéricos , Neoplasias do Colo do Útero/patologia , Esfregaço Vaginal , Adulto Jovem , Displasia do Colo do Útero/patologia
8.
J Gen Virol ; 91(Pt 7): 1849-53, 2010 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-20219899

RESUMO

Serology has been used to indicate past infection by the human polyomaviruses BK virus (BKV) and JC virus (JCV), because the site of primary infection is not established fully. Little is known about BKV and JCV antibody stability over time. We investigated BKV and JCV seroprevalence and antibody stability over time in an Australian population-based study. Serum was collected from 458 adults participating in a longitudinal skin cancer study in Queensland in 1992, 1993 and 1996, and 117 people had a fourth sample collected in 2003. Serum samples were analysed for BKV and JCV VP1 antibodies by multiplex detection using the Luminex platform. The seroprevalence for BKV and JCV over 4.5 years was 97 and 63 %, respectively. The BKV seroprevalence was 99 % in 25-60-year-olds, and 94 % in people older than 60 years. JCV seroprevalence was around 60 % in people younger than 50 years, 68 % in people 50-70 years of age and 64 % in people older than 70 years. BKV seroprevalence was very stable over 11 years, with 96 % of people staying seropositive and 2 % remaining seronegative. JCV antibody status over time was less stable; 57 % of participants remained seropositive and 31 % seronegative. The same proportion of people (4 % each) seroconverted, seroreverted or had fluctuating JCV antibody levels. These results confirm the previously believed stability of polyomavirus antibodies, with BKV antibodies being highly stable and JCV antibodies moderately so. Thus, a single measure can be used as a reasonable indicator of long-term antibody status in epidemiological studies aiming to understand associations between polyomaviruses and disease.


Assuntos
Anticorpos Antivirais/sangue , Vírus BK/imunologia , Vírus JC/imunologia , Infecções por Polyomavirus/imunologia , Infecções Tumorais por Vírus/imunologia , Adulto , Distribuição por Idade , Idoso , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Infecções por Polyomavirus/epidemiologia , Infecções por Polyomavirus/virologia , Estudos Soroepidemiológicos , Fatores de Tempo , Infecções Tumorais por Vírus/epidemiologia , Infecções Tumorais por Vírus/virologia
9.
Aust N Z J Obstet Gynaecol ; 50(3): 242-5, 2010 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-20618241

RESUMO

OBJECTIVE: The objective of this study was to assess the association between transfusion, per cent drop in haemoglobin (Hb), and estimated blood loss during the delivery and the first postoperative week following caesarean delivery for placenta praevia. Clinical data predictive of an objective laboratory test for risk of haemorrhage and the need for transfusion were investigated. Transfusions outside national Guidelines were noted. DESIGN: Retrospective observational study of patients with placenta praevia, who were delivered consecutively by caesarean section at Royal Brisbane and Women's Hospital from 1999 to 2005. SETTING: University-affiliated tertiary hospital. All caesareans were performed by one or more consultant obstetricians, gynaecology oncology surgeons and registrar assistants. RESULTS: Seventy-one (28.9%) of 246 patients with placenta praevia were transfused, with 45 of these receiving three or more red cell units. The antenatal Hb fell by a mean of 20.2% (SD 13.5). The average operative haemorrhage was estimated as 1225 mL (SD 996). No patient or surgical factors were significantly associated with changes in Hb. There was a significant association between per cent fall in antenatal Hb and both transfusion P < 0.001 and estimated loss P = 0.002. After transfusion, the Hb of 19 patients was higher than that recommended by Guidelines. CONCLUSIONS: Whether transfusion is necessary, but not the number of red cell units, can be planned by the effect of haemorrhage on antenatal Hb during delivery by caesarean section complicated by placenta praevia.


Assuntos
Cesárea , Transfusão de Eritrócitos , Hemorragia/terapia , Placenta Prévia/cirurgia , Adulto , Perda Sanguínea Cirúrgica , Cesárea/efeitos adversos , Feminino , Hemoglobinas/análise , Humanos , Placenta Prévia/sangue , Gravidez , Estudos Retrospectivos
10.
Public Health Nutr ; 12(12): 2359-65, 2009 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-19257921

RESUMO

OBJECTIVE: To assess the reproducibility of a 135-item self-administered semi-quantitative FFQ. DESIGN: Control subjects who had previously completed an FFQ relating to usual dietary intake in a nationwide case-control study of cancer between November 2003 and April 2004 were randomly selected, re-contacted, and invited to complete the same FFQ a second time approximately one year later (between January and April 2005). Agreement between the two FFQ was compared using weighted kappa statistics and intraclass correlation coefficients (ICC) for food groups and nutrients. Summary questions, included in the FFQ, were used to assess overall intakes of vegetables, fruits and meat. SETTING: General community in Australia. SUBJECTS: One hundred men and women aged 22-79 years, randomly selected from the previous control population. RESULTS: The weighted kappa and ICC measures of agreement for food groups were moderate to substantial for seventeen of the eighteen food groups. For nutrients, weighted kappa ranged from 0.44 for starch to 0.83 for alcohol while ICC ranged from 0.51 to 0.91 for the same nutrients. Estimates of meat, fruit and vegetable intake using summary questions were similar for both survey periods, but were significantly lower than estimates from summed individual food items. CONCLUSIONS: The FFQ produced reproducible results and is reasonable in assessing the usual intake of various foods and nutrients among an Australian adult population.


Assuntos
Inquéritos sobre Dietas , Dieta , Inquéritos e Questionários/normas , Adulto , Idoso , Austrália , Feminino , Frutas , Humanos , Masculino , Carne , Pessoa de Meia-Idade , Avaliação Nutricional , Reprodutibilidade dos Testes , Sensibilidade e Especificidade , Estatísticas não Paramétricas , Verduras , Adulto Jovem
11.
Aust Health Rev ; 32(1): 23-33, 2008 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-18241146

RESUMO

A critical review was conducted of the literature from 1960 to June 2005 on service quality in type 2 diabetes. The review demonstrated that improving service quality may improve the outcomes for people with type 2 diabetes. The potential service quality factors from the perspective of people with type 2 diabetes were: timeliness, confidentiality, continuity, dignity, communication, access, education, cost, amenities and autonomy.


Assuntos
Atenção à Saúde/normas , Diabetes Mellitus Tipo 2 , Satisfação do Paciente , Austrália , Programas Nacionais de Saúde , Projetos de Pesquisa
12.
Aust N Z J Public Health ; 31(6): 511-5, 2007 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-18081568

RESUMO

OBJECTIVES: To explore the needs, expectations, feelings and experiences of people with type 2 diabetes for developing quantitative instruments for a questionnaire study of service quality. METHODS: Using two focus group discussions (n=33), potential service quality dimensions for type 2 diabetes were assessed for Australian relevance. These included 11 indicators identified from a systematic literature review: communication, autonomy, choice of care provider, continuity of care, quality of basic amenities, dignity, timeliness, prevention and early detection, safety, confidentiality and availability. RESULTS: The focus group discussions supported the importance of the 11 service quality indicators but gave more importance to education, diet, communication, autonomy, choice of care provider and support group and less to confidentiality and availability. Three new themes were generated from the discussions: education, diet and support group. CONCLUSION: Measuring service quality for type 2 diabetes requires considering health system, culture and disease-specific factors.


Assuntos
Diabetes Mellitus Tipo 2 , Satisfação do Paciente , Percepção , Qualidade da Assistência à Saúde/normas , Adulto , Idoso , Idoso de 80 Anos ou mais , Austrália , Feminino , Grupos Focais , Pesquisas sobre Atenção à Saúde , Humanos , Masculino , Pessoa de Meia-Idade , Pesquisa Qualitativa , Queensland , Inquéritos e Questionários
13.
Community Dent Oral Epidemiol ; 34(1): 25-35, 2006 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-16423028

RESUMO

OBJECTIVES: The aim of this study was to investigate the association between selected social and behavioural variables and the pattern and severity of early childhood caries (ECC) within a community child population. METHODS: A cross-sectional sample of 2515 children aged 4-5 years were examined in a preschool setting using decayed, missing, filled teeth/surface (dmft/dmfs) indices and a self-administered questionnaire was used to obtain information regarding social, demographic, birth, infant feeding, oral and general health attitudes. Children with caries (847) were divided into anterior or posterior caries pattern groups and severe (dmfs score > or =6) or non-severe (dmfs score <6) caries groups. The data were analysed using a chi-square test and modelled using a logistic regression procedure. RESULTS: Significant variables associated with anterior ECC pattern were ethnicity other than Caucasian (OR = 2.1, 95% CI = 1.4-3.1), sipping from the bottle during the day (OR = 1.9, 95% CI = 1.3-2.7), male gender (OR = 1.6, 95% CI = 1.2-2.2) and sleeping with a bottle at night (OR = 1.5, 95% CI = 1.1-2.2). Significant variables associated with severe ECC form were sipping from the bottle during the day (OR = 2, 95% CI = 1.4-2.8), maternal age at birth < or =24 years (OR = 1.8, 95% CI = 1.3-2.7), ethnicity other than Caucasian (OR = 1.6, 95% CI = 1.1-2.5) and sleeping with a bottle at night (OR = 1.5, 95% CI = 1.1-2.2). CONCLUSIONS: Infant bottle-feeding habits (either allowing a child to sip from a bottle during the day or put to sleep at night) and ethnicity other than Caucasian were significant determinants for both anterior caries pattern and severity of ECC in 4-5-year-old Australian children.


Assuntos
Índice CPO , Cárie Dentária/classificação , Adulto , Atitude Frente a Saúde , Bebidas , Alimentação com Mamadeira , Pré-Escolar , Estudos Transversais , Carboidratos da Dieta/administração & dosagem , Tratamento Farmacológico , Etnicidade , Feminino , Humanos , Masculino , Idade Materna , Chupetas , Fatores Sexuais , Sono , Classe Social , Escovação Dentária , Cremes Dentais/uso terapêutico
14.
Aust Health Rev ; 30(1): 46-55, 2006 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-16448377

RESUMO

This paper describes the implementation and evaluation of a three-way model of service development mentoring. This population health mentoring program was funded by the Commonwealth Department of Health and Ageing to enable staff from eight Divisions of General Practice in South Australia to gain a sound understanding of population health concepts relevant to their workplace. The distinguishing features of service development mentoring were that the learning was grounded within an individual's work setting and experience; there was an identified population health problem or issue confronting the Division of General Practice; and there was an expectation of enhanced organisational performance. A formal evaluation found a consensus among all learners that mentoring was a positive and worthwhile experience, where they had achieved what they had set out to do. Mentors found the model of learning agreeable and effective. Division executive officers recognised enhanced skills among their "learner" colleagues, and commented positively on the benefits to their organisations through the development of well researched and relevant projects, with the potential to improve the efficiency of their population health activities.


Assuntos
Medicina de Família e Comunidade/organização & administração , Mentores , Humanos , Satisfação no Emprego , Modelos Organizacionais , Resolução de Problemas , Austrália do Sul
16.
Community Dent Health ; 19(4): 237-42, 2002 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-12489838

RESUMO

OBJECTIVES: Early childhood caries (ECC) has been suggested as a new term to describe the presence of caries on at least one primary tooth in children under six years of age. The prevalence and severity of ECC in low socio-economic, immigrant and indigenous communities is high. The purpose of this study was to investigate the association between selected social and behavioural variables, including previous infant feeding practice, and the presence of ECC in an Australian child population. METHOD: A cross sectional sample of 3,375 four to six-year-old children from the north Brisbane region were examined in a school based setting using dmft/s indices and a self-administered questionnaire obtained information regarding social background and past infant feeding practice. The data were modelled using a forward stepwise logistic regression procedure to explore a statistical model for ECC presence. RESULTS: Significant determinants for ECC presence were ethnicity other than Caucasian (OR=1.99, CI=1.37, 2.88), language other than English (OR=1.97, CI=1.35, 2.86), single parent status (OR=1.93, CI=1.47, 2.52), sweetened bottle contents (OR=4.29, CI=2.90, 6.38), going to sleep with the bottle (OR=1.73, CI=1.49, 2.00) and sipping from the bottle during the day (OR=1.58, CI=1.35, 1.84). CONCLUSIONS: A statistical model for ECC presence and previous infant feeding practice has been constructed. This study supports the adoption of the proposed case definition of ECC.


Assuntos
Alimentação com Mamadeira/estatística & dados numéricos , Aleitamento Materno/estatística & dados numéricos , Cárie Dentária/epidemiologia , Dente Decíduo/patologia , Bebidas/estatística & dados numéricos , Criança , Pré-Escolar , Estudos de Coortes , Intervalos de Confiança , Estudos Transversais , Índice CPO , Etnicidade/estatística & dados numéricos , Comportamento Alimentar , Humanos , Lactente , Alimentos Infantis/estatística & dados numéricos , Idioma , Modelos Logísticos , Razão de Chances , Higiene Bucal/estatística & dados numéricos , Queensland/epidemiologia , Grupos Raciais , Família Monoparental/estatística & dados numéricos , Classe Social
17.
Disabil Rehabil ; 25(9): 433-40, 2003 May 06.
Artigo em Inglês | MEDLINE | ID: mdl-12745938

RESUMO

PURPOSE: This study measured reliability between stroke patients' and significant others' scores on items on the Reintegration to Normal Living (RNL) Index and whether there were any scoring biases. METHOD: The 11-item RNL Index was administered to 57 pairs of patients and significants six months after stroke rehabilitation. The index was scored using a 10-point visual analogue scale. Patient and significant other demographic information and data on patients' clinical, functional and cognitive status were collected. Reliability was measured using the intra-class correlation coefficient (ICC) and percent agreement. RESULTS: Overall poor reliability was found for the RNL Index total score (ICC=.36, 95% CI .07 to .59) and the daily functioning subscale (ICC=.24, 95% Cl -.003 to .46) and moderate reliability was found for the perception of self subscale (ICC= .55, 95% Cl .28 to .73). There was a moderate bias for patients to rate themselves as achieving better reintegration than was indicated by significant others, although no demographic or clinical factors were associated with this bias. Exact match agreement was best for the subjective items and worse for items reflecting mobility around the community and participation in a work activity. CONCLUSIONS: Caution is needed when interpreting patient information reported by significant others on the RNL Index. The use of a shorter scale to rate the RNL Index requires investigation.


Assuntos
Atividades Cotidianas , Família , Reabilitação do Acidente Vascular Cerebral , Adulto , Idoso , Idoso de 80 Anos ou mais , Análise de Variância , Avaliação da Deficiência , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Qualidade de Vida , Queensland/epidemiologia , Reprodutibilidade dos Testes , Acidente Vascular Cerebral/epidemiologia
18.
Neurol Res ; 36(9): 779-85, 2014 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-24620985

RESUMO

OBJECTIVES: Ascent to high altitude may result in a hypobaric hypoxic brain injury. The development of acute mountain sickness (AMS) is considered a multifactorial process with hypoxia-induced blood-brain barrier (BBB) dysfunction and resultant vasogenic oedema cited as one potential mechanism. Peripheral S100B is considered a biomarker of BBB dysfunction. This study aims to investigate the S100B release profile secondary to hypoxic brain injury and comment on BBB disturbance and AMS. METHODS: A prospective field study of 12 subjects who ascended Mt Fuji (3700 m) was undertaken. RESULTS: The mean baseline plasma S100B level was 0·11 µg/l (95% CI 0·09-0·12), which increased to 0·22 µg/l (95% CI 0·17-0·27) at the average of three high altitude levels (2590, 3700, and 2590 m on descent) (P < 0·001). The mean level for the seven subjects who experienced AMS rose from 0·10 to 0·19 µg/l compared to 0·12 to 0·25 µg/l for the five subjects who did not develop AMS (P  =  0·33). CONCLUSION: Ascending to 3700 m resulted in elevated plasma S100B levels but this was not associated with AMS.


Assuntos
Doença da Altitude/sangue , Hipóxia/sangue , Subunidade beta da Proteína Ligante de Cálcio S100/sangue , Adulto , Altitude , Feminino , Humanos , Hipóxia/etiologia , Masculino , Pessoa de Meia-Idade , Oxigênio/sangue , Estudos Prospectivos , Adulto Jovem
19.
Pediatr Dent ; 35(7): 523-8, 2013.
Artigo em Inglês | MEDLINE | ID: mdl-24553276

RESUMO

PURPOSE: The purpose of this study was to evaluate a chairside caries risk assessment protocol utilizing a caries prediction instrument, adenosine triphosphate (ATP) activity in dental plaque, mutans streptococci (MS) culture, and routine dental examination in five- to 10-year-old children at two regional Australian schools with high caries experience. METHODS: Clinical indicators for future caries were assessed at baseline examination using a standardized prediction instrument. Plaque ATP activity was measured directly in relative light units (RLU) using a bioluminescence meter, and MS culture data were recorded. Each child's dentition was examined clinically and radiographically, and caries experience was recorded using enamel white spot lesions and decayed, missing, and filled surfaces for primary and permanent teeth indices. Univariate one-way analysis of variance between selected clinical indicators, ATP activity, MS count at baseline, and future new caries activity was performed, and a generalized linear model for prediction of new caries activity at 24 months was constructed. RESULTS: Future new caries activity was significantly associated with the presence of visible cavitations, reduced saliva flow, and orthodontic appliances at baseline (R(2)=0.2, P<.001). CONCLUSION: Baseline plaque adenosine triphosphate activity and mutans streptococci counts were not significantly associated with caries activity at 24 months.


Assuntos
Índice CPO , Suscetibilidade à Cárie Dentária/fisiologia , Placa Dentária/química , Streptococcus mutans/isolamento & purificação , Trifosfato de Adenosina/análise , Carga Bacteriana , Criança , Pré-Escolar , Cárie Dentária/diagnóstico , Testes de Atividade de Cárie Dentária , Placa Dentária/microbiologia , Seguimentos , Previsões , Humanos , Modelos Lineares , Substâncias Luminescentes , Medições Luminescentes/métodos , Aparelhos Ortodônticos , Placebos , Estudos Prospectivos , Medição de Risco , Saliva/metabolismo , Taxa Secretória/fisiologia , Classe Social , Dente Decíduo/patologia , Saúde da População Urbana
20.
Women Birth ; 25(2): 79-85, 2012 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-21295531

RESUMO

BACKGROUND: This study took place in a remote community on the Ngaanyatjarra Lands, Western Australia. Ngaanyatjarra women's cultural practices have been subject to erosion during the past 70 years. Women are now expected to birth hundreds of kilometres from home and, due to financial barriers, without family support. Older women lament their lack of input into, and control of, contemporary birthing services. RESEARCH QUESTION: In order to provide culturally appropriate maternity services we asked: What issues would the Ngaanyatjarra women of the community like to see resolved in the area of antenatal and birthing services? PARTICIPANTS AND METHODS: Eligible participants were any Ngaanyatjarra women of the study community who had birthed at least once. We utilised a participatory research methodology. 36 women were interviewed. FINDINGS: This paper discusses one finding related to support for child-bearing women. The role is important in many ways. Ngaanyatjarra women did not traditionally have their support persons with them during labour and birth, nor do they necessarily expect them to be present in current times. Most women do, however, wish to have a support person with them during antenatal checkups and when they travel to town to await birth. CONCLUSION: Aboriginal women from remote communities should be able to have a support person with them when they access regional birthing services, but the nature of this role must not be assumed. A culturally appropriate service has input from the community, provides options and respects choices.


Assuntos
Serviços de Saúde do Indígena/organização & administração , Serviços de Saúde Materna/organização & administração , Havaiano Nativo ou Outro Ilhéu do Pacífico/psicologia , Parto/etnologia , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Pesquisa Participativa Baseada na Comunidade , Feminino , Conhecimentos, Atitudes e Prática em Saúde , Humanos , Entrevistas como Assunto , Pessoa de Meia-Idade , Tocologia , Parto/psicologia , Gravidez , Características de Residência , População Rural , Apoio Social , Austrália Ocidental , Adulto Jovem
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