Detalhe da pesquisa
1.
Piperazine-2-carboxylic acid derivatives as MTDLs anti-Alzheimer agents: Anticholinesterase activity, mechanistic aspect, and molecular modeling studies.
Bioorg Chem
; 142: 106916, 2024 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37913584
2.
Synthesis, in vitro anticancer activity and in silico studies of certain isoxazole-based carboxamides, ureates, and hydrazones as potential inhibitors of VEGFR2.
Bioorg Chem
; 116: 105334, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34534755
3.
Synthesis, in vitro anticancer activity and in silico studies of certain pyrazole-based derivatives as potential inhibitors of cyclin dependent kinases (CDKs).
Bioorg Chem
; 116: 105347, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34555628
4.
Synthesis, antimicrobial activity and molecular modeling study of 3-(5-amino-(2H)-1,2,4-triazol-3-yl]-naphthyridinones as potential DNA-gyrase inhibitors.
Bioorg Chem
; 81: 599-611, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30248511
5.
Hesperidin hexosomal loaded nanodispersion: insights of its antimycobacterial, cytotoxic and anti-HCoV effects.
Nat Prod Res
; 37(10): 1719-1724, 2023 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-35921497
6.
Design, Synthesis, Molecular Modeling, Biological Activity, and Mechanism of Action of Novel Amino Acid Derivatives of Norfloxacin.
ACS Omega
; 8(45): 43271-43284, 2023 Nov 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38024743
7.
Rational design, synthesis, molecular modeling, biological activity, and mechanism of action of polypharmacological norfloxacin hydroxamic acid derivatives.
RSC Med Chem
; 14(12): 2593-2610, 2023 Dec 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-38099058
8.
N4-Substituted Piperazinyl Norfloxacin Derivatives with Broad-Spectrum Activity and Multiple Mechanisms on Gyrase, Topoisomerase IV, and Bacterial Cell Wall Synthesis.
ACS Bio Med Chem Au
; 3(6): 494-506, 2023 Dec 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-38144255
9.
UPLC-MS/MS and GC-MS based metabolites profiling of Moringa oleifera seed with its anti- Helicobacter pylori and anti-inflammatory activities.
Nat Prod Res
; 36(24): 6433-6438, 2022 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-35133224
10.
Mechanistic selectivity investigation and 2D-QSAR study of some new antiproliferative pyrazoles and pyrazolopyridines as potential CDK2 inhibitors.
Eur J Med Chem
; 218: 113389, 2021 Jun 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33784602
11.
Biotransformation studies of prednisone using human intestinal bacteria Part II: Anaerobic incubation and docking studies.
J Enzyme Inhib Med Chem
; 24(6): 1211-9, 2009 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-19912054
12.
Anti-hepatitis-C virus activity and QSAR study of certain thiazolidinone and thiazolotriazine derivatives as potential NS5B polymerase inhibitors.
Eur J Med Chem
; 184: 111747, 2019 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31604164
13.
Ambrosin, a potent NF-κß inhibitor, ameliorates lipopolysaccharide induced memory impairment, comparison to curcumin.
PLoS One
; 14(7): e0219378, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31276550