Detalhe da pesquisa
1.
Decreases in different Dnmt3b activities drive distinct development of hematologic malignancies in mice.
J Biol Chem
; 296: 100285, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33450231
2.
Dnmt3a Is a Haploinsufficient Tumor Suppressor in CD8+ Peripheral T Cell Lymphoma.
PLoS Genet
; 12(9): e1006334, 2016 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-27690235
3.
Mouse development with a single E2F activator.
Nature
; 454(7208): 1137-41, 2008 Aug 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-18594513
4.
Genome-wide methylation profiling of Peripheral T-cell lymphomas identifies TRIP13 as a critical driver of tumor proliferation and survival.
Res Sq
; 2024 Feb 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-38464090
5.
Dnmt3b catalytic activity is critical for its tumour suppressor function in lymphomagenesis and is associated with c-Met oncogenic signalling.
EBioMedicine
; 63: 103191, 2021 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-33418509
6.
Catalytically inactive Dnmt3b rescues mouse embryonic development by accessory and repressive functions.
Nat Commun
; 10(1): 4374, 2019 09 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-31558711
7.
Loss of Dnmt3a induces CLL and PTCL with distinct methylomes and transcriptomes in mice.
Sci Rep
; 6: 34222, 2016 Sep 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-27677595
8.
Promoter Hypomethylation and Expression Is Conserved in Mouse Chronic Lymphocytic Leukemia Induced by Decreased or Inactivated Dnmt3a.
Cell Rep
; 15(6): 1190-201, 2016 05 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27134162
9.
Methylation-independent repression of Dnmt3b contributes to oncogenic activity of Dnmt3a in mouse MYC-induced T-cell lymphomagenesis.
Oncogene
; 34(43): 5436-5446, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25639876
10.
Essential role for Dnmt1 in the prevention and maintenance of MYC-induced T-cell lymphomas.
Mol Cell Biol
; 33(21): 4321-33, 2013 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-24001767
11.
Loss of Dnmt3b function upregulates the tumor modifier Ment and accelerates mouse lymphomagenesis.
J Clin Invest
; 122(1): 163-77, 2012 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-22133874
12.
Specific tumor suppressor function for E2F2 in Myc-induced T cell lymphomagenesis.
Proc Natl Acad Sci U S A
; 104(39): 15400-5, 2007 Sep 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-17881568
13.
Extra-embryonic function of Rb is essential for embryonic development and viability.
Nature
; 421(6926): 942-7, 2003 Feb 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-12607001