Detalhe da pesquisa
1.
Selective antagonism of the hepatic glucocorticoid receptor reduces hepatic glucose production.
Metabolism
; 55(9): 1255-62, 2006 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-16919547
2.
Metabolic responses with endothelin antagonism in a model of insulin resistance.
Metabolism
; 54(6): 735-40, 2005 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-15931607
3.
The success of bariatric surgery as treatment of type 2 diabetes should be a call to revitalize anti-obesity drug discovery and development.
Curr Opin Investig Drugs
; 9(4): 355-6, 2008 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-18393101
4.
Blood pressure regulation by ETA and ETB receptors in conscious, telemetry-instrumented mice and role of ETA in hypertension produced by selective ETB blockade.
Am J Physiol Heart Circ Physiol
; 290(6): H2554-9, 2006 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-16399858
5.
Delivery of RNAi reagents in murine models of obesity and diabetes.
J RNAi Gene Silencing
; 3(1): 225-36, 2006 Nov 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-19771218
6.
Hepatic glucocorticoid receptor antagonism is sufficient to reduce elevated hepatic glucose output and improve glucose control in animal models of type 2 diabetes.
J Pharmacol Exp Ther
; 314(1): 191-200, 2005 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-15784656
7.
Hypertension induced by blockade of ET(B) receptors in conscious nonhuman primates: role of ET(A) receptors.
Am J Physiol Heart Circ Physiol
; 283(4): H1555-61, 2002 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-12234809
8.
Effects of a selective ET(A)-receptor antagonist, atrasentan (ABT-627), in murine models of allergic asthma: demonstration of mouse strain specificity.
Clin Sci (Lond)
; 103 Suppl 48: 367S-370S, 2002 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-12193124
9.
Effects of a selective endothelin A receptor antagonist, ABT-627, in healthy normotensive anaesthetized rats developing acute pulmonary air embolism.
Clin Sci (Lond)
; 103 Suppl 48: 371S-375S, 2002 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-12193125
10.
Pharmacology of endothelin receptor antagonists ABT-627, ABT-546, A-182086 and A-192621: in vitro studies.
Clin Sci (Lond)
; 103 Suppl 48: 107S-111S, 2002 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-12193066
11.
Pharmacology of endothelin receptor antagonists ABT-627, ABT-546, A-182086 and A-192621: ex vivo and in vivo studies.
Clin Sci (Lond)
; 103 Suppl 48: 112S-117S, 2002 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-12193067
12.
PTP1B antisense oligonucleotide lowers PTP1B protein, normalizes blood glucose, and improves insulin sensitivity in diabetic mice.
Proc Natl Acad Sci U S A
; 99(17): 11357-62, 2002 Aug 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-12169659