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1.
Health Econ ; 30(1): 70-85, 2021 01.
Artigo em Inglês | MEDLINE | ID: mdl-33094548

RESUMO

We introduce a summary wellbeing measure for economic evaluation of cross-sectoral public policies with impacts on health and living standards. We show how to calculate period-specific and lifetime wellbeing using quality-adjusted life years based on widely available data on health-related quality of life and consumption and normative assumptions about three parameters-minimal consumption, standard consumption, and the elasticity of the marginal value of consumption. We also illustrate how these three parameters can be tailored to the decision-making context and varied in sensitivity analysis to provide information about the implications of alternative value judgments. As well as providing a general measure for cost-effectiveness analysis and cost-benefit analysis in terms of wellbeing, this approach also facilitates distributional analysis in terms of how many good years different population subgroups can expect to live under different policy scenarios.


Assuntos
Qualidade de Vida , Análise Custo-Benefício , Humanos , Anos de Vida Ajustados por Qualidade de Vida
2.
Sci Rep ; 9(1): 19222, 2019 Dec 11.
Artigo em Inglês | MEDLINE | ID: mdl-31822773

RESUMO

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

3.
Sci Rep ; 9(1): 11054, 2019 07 30.
Artigo em Inglês | MEDLINE | ID: mdl-31363134

RESUMO

We evaluate the total probability of human extinction from naturally occurring processes. Such processes include risks that are well characterized such as asteroid impacts and supervolcanic eruptions, as well as risks that remain unknown. Using only the information that Homo sapiens has existed at least 200,000 years, we conclude that the probability that humanity goes extinct from natural causes in any given year is almost guaranteed to be less than one in 14,000, and likely to be less than one in 87,000. Using the longer track record of survival for our entire genus Homo produces even tighter bounds, with an annual probability of natural extinction likely below one in 870,000. These bounds are unlikely to be affected by possible survivorship bias in the data, and are consistent with mammalian extinction rates, typical hominin species lifespans, the frequency of well-characterized risks, and the frequency of mass extinctions. No similar guarantee can be made for risks that our ancestors did not face, such as anthropogenic climate change or nuclear/biological warfare.


Assuntos
Mudança Climática , Ecossistema , Extinção Biológica , Humanos , Probabilidade
4.
Am J Bioeth ; 8(7): 12-9, 2008 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-18759175

RESUMO

It is often claimed that from the moment of conception embryos have the same moral status as adult humans. This claim plays a central role in many arguments against abortion, in vitro fertilization, and stem cell research. In what follows, I show that this claim leads directly to an unexpected and unwelcome conclusion: that natural embryo loss is one of the greatest problems of our time and that we must do almost everything in our power to prevent it. I examine the responses available to those who hold that embryos have full moral status and conclude that they cannot avoid the force of this argument without giving up this key claim.


Assuntos
Início da Vida Humana/ética , Perda do Embrião , Mortalidade Fetal , Obrigações Morais , Pessoalidade , Valor da Vida , Aborto Espontâneo , Adulto , Temas Bioéticos , Implantação do Embrião , Perda do Embrião/prevenção & controle , Análise Ética , Feminino , Fertilização in vitro/ética , Morte Fetal/prevenção & controle , Humanos , Expectativa de Vida , Gravidez , Criação de Embriões para Pesquisa/ética , Taxa de Sobrevida , Estados Unidos/epidemiologia
5.
Sci Rep ; 8(1): 1015, 2018 01 17.
Artigo em Inglês | MEDLINE | ID: mdl-29343692

RESUMO

We introduce new theoretical insights into two-population asymmetric games allowing for an elegant symmetric decomposition into two single population symmetric games. Specifically, we show how an asymmetric bimatrix game (A,B) can be decomposed into its symmetric counterparts by envisioning and investigating the payoff tables (A and B) that constitute the asymmetric game, as two independent, single population, symmetric games. We reveal several surprising formal relationships between an asymmetric two-population game and its symmetric single population counterparts, which facilitate a convenient analysis of the original asymmetric game due to the dimensionality reduction of the decomposition. The main finding reveals that if (x,y) is a Nash equilibrium of an asymmetric game (A,B), this implies that y is a Nash equilibrium of the symmetric counterpart game determined by payoff table A, and x is a Nash equilibrium of the symmetric counterpart game determined by payoff table B. Also the reverse holds and combinations of Nash equilibria of the counterpart games form Nash equilibria of the asymmetric game. We illustrate how these formal relationships aid in identifying and analysing the Nash structure of asymmetric games, by examining the evolutionary dynamics of the simpler counterpart games in several canonical examples.


Assuntos
Jogos Experimentais , Modelos Estatísticos , Feminino , Teoria dos Jogos , Humanos , Masculino
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