RESUMO
The positional distribution of fatty acids in choline- and ethanolamine phosphoglycerides from the livers of polycystic disease-bearing rats and stomachs of gastric tumor-bearing rats was analyzed and compared to that in normal rat liver and stomach. Polycystic disease and gastric tumors were induced with N-Methyl-N'-Nitro-N-Nitrosoguanidine. There was no significant difference between diseased and normal organs with respect to the composition of fatty acids at the 1-position, except that diseased livers exhibited an increase of approximately 22% in 16: 0 fatty acid and a decrease of approximately 12% in 18: 1 fatty acid. However, in diseased organs, there were marked quantitative changes in the positional distribution of fatty acids at the 2-position, their composition exhibiting greater saturation. Furthermore, in diseased organs, there was an increase in 15: 0 fatty acid at the 2-position of ethanolamine phosphoglycerides.
RESUMO
In Vietnam, increasing fat consumption is a trend recognized recently in urban areas. To obtain a reasonable nutrition status and prevent cardiovascular disease (CVD), it is necessary to obtain information on habitual fat intake and biochemical parameters as risk factors for CVD in Vietnamese populations. Therefore, from the analysis of serum fatty acid composition, fat consumption patterns in Vietnamese populations in South Vietnam, with different incomes, are discussed in this study. In addition, some risk factors for premature CVD, serum lipoprotein (a) and apolipoprotein concentrations are also assessed in these Vietnamese populations. The study was carried out in men and women aged 40-59 in three different districts: urban (n = 100), suburban (n = 98) and rural (n = 98). The results of serum fatty acid composition analysis reflected differences in quality fat intake among the three populations. The urban population was estimated to consume more vegetable oil but less fish than their rural counterparts. Although serum lipoprotein (a) and apolipoprotein B levels were below the ranges associated with atherogenesis, ongoing attention to dietary fat intake for the prevention of CVD in Vietnamese populations is required.