Mandibular osteomyelitis caused by Blastoschizomyces capitatus in a child with acute myelogenous leukemia.

A 6-year-old girl with acute myelogenous leukemia (AML) developed fungal mandibular osteomyelitis during chemotherapy. Blastoschizomyces capitatus was recognized histologically by its yeast-like morphology and formation of annelloconidia, and was confirmed by culture. The fungal osteomyelitis of the mandible was treated successfully with prolonged antifungal medication, extensive surgical debridement and an oral care program, without interrupting leukemia chemotherapy. B. capitatus osteomyelitis of the mandible may occur during chemotherapy in AML patients with poor dental condition. Successful treatment can be achieved by careful management without interruption of antineoplastic chemotherapy.

[The management of chemically burned oral tissue--a case report].

Oral and perioral burns often result in post-healing microstoma, a shallow vestibule, tongue ankylosis, esthetic problems, and masticatory and speech impairments. The main cause being persistent extensive scar tissue contractions during the healing process. These disastrous sequelae can be minimized by surgical reconstruction. Use of special prosthesis may be required to provide scar tissue with the physical ability to resist contraction in post-injury and post-surgery stages. A twenty-eight-year old female was admitted to Makay Memorial Hospital in October 1986, with chemicals burn over the lower face, involving both upper and lower lips, and the entire oral mucosa. The patient had accidentally swallowed a corrosive detergent (Drano). Microstomia and tongue ankylosis developed within three months. Surgical reconstruction with the use of special oral prostheses (a commissure splint, angular retractor, and mouth protector) was conducted to counteract scar tissue contractions. Within two years of follow up, results were acceptable. The patient is presently able to open her mouth wide enough for both mastication and speech.