Detalhe da pesquisa
1.
Substitution of Met-38 to Ile in γ-synuclein found in two patients with amyotrophic lateral sclerosis induces aggregation into amyloid.
Proc Natl Acad Sci U S A
; 121(2): e2309700120, 2024 Jan 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-38170745
2.
Targeting Biomolecular Condensation and Protein Aggregation against Cancer.
Chem Rev
; 123(14): 9094-9138, 2023 07 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-37379327
3.
α-Synuclein phosphorylation at serine 129 occurs after initial protein deposition and inhibits seeded fibril formation and toxicity.
Proc Natl Acad Sci U S A
; 119(15): e2109617119, 2022 04 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35353605
4.
Alpha-synuclein overexpression induces epigenomic dysregulation of glutamate signaling and locomotor pathways.
Hum Mol Genet
; 31(21): 3694-3714, 2022 10 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-35567546
5.
Regional AT-8 reactive tau species correlate with intracellular Aß levels in cases of low AD neuropathologic change.
Acta Neuropathol
; 147(1): 40, 2024 Feb 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38353753
6.
Basic Science in Movement Disorders: Fueling the Engine of Translation into Clinical Practice.
Mov Disord
; 2024 Apr 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-38576081
7.
DEAD-box RNA helicase Dbp4/DDX10 is an enhancer of α-synuclein toxicity and oligomerization.
PLoS Genet
; 17(3): e1009407, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33657088
8.
The small aromatic compound SynuClean-D inhibits the aggregation and seeded polymerization of multiple α-synuclein strains.
J Biol Chem
; 298(5): 101902, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35390347
9.
Proteomic analysis of the human hippocampus identifies neuronal pentraxin 1 (NPTX1) as synapto-axonal target in late-stage Parkinson's disease.
J Neurochem
; 166(5): 862-874, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37515330
10.
Glycosylation spectral signatures for glioma grade discrimination using Raman spectroscopy.
BMC Cancer
; 23(1): 174, 2023 Feb 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-36809974
11.
Extracellular Vesicles for the Diagnosis of Parkinson's Disease: Systematic Review and Meta-Analysis.
Mov Disord
; 38(9): 1585-1597, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37449706
12.
Defining the Riddle in Order to Solve It: There Is More Than One "Parkinson's Disease".
Mov Disord
; 38(7): 1127-1142, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37156737
13.
Prion-like α-synuclein pathology in the brain of infants with Krabbe disease.
Brain
; 145(4): 1257-1263, 2022 05 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-34999780
14.
Hexokinase 2: The preferential target of trehalose-6-phosphate over hexokinase 1.
J Cell Biochem
; 123(11): 1808-1816, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35944097
15.
Extracellular alpha-synuclein: Sensors, receptors, and responses.
Neurobiol Dis
; 168: 105696, 2022 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35321855
16.
Glyoxal as an alternative fixative to formaldehyde in immunostaining and super-resolution microscopy.
EMBO J
; 37(1): 139-159, 2018 01 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29146773
17.
Cellular Prion Protein Mediates α-Synuclein Uptake, Localization, and Toxicity In Vitro and In Vivo.
Mov Disord
; 37(1): 39-51, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34448510
18.
Cerebral dopamine neurotrophic factor reduces α-synuclein aggregation and propagation and alleviates behavioral alterations in vivo.
Mol Ther
; 29(9): 2821-2840, 2021 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33940158
19.
Nuclear localization and phosphorylation modulate pathological effects of alpha-synuclein.
Hum Mol Genet
; 28(1): 31-50, 2019 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30219847
20.
Lipids, lysosomes and mitochondria: insights into Lewy body formation from rare monogenic disorders.
Acta Neuropathol
; 141(4): 511-526, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33515275