Detalhe da pesquisa
1.
Aggregation and beyond: alpha-synuclein-based biomarkers in synucleinopathies.
Brain
; 147(1): 81-90, 2024 01 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37526295
2.
The lysosomal ß-glucocerebrosidase strikes mitochondria: implications for Parkinson's therapeutics.
Brain
; 2024 Mar 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-38437875
3.
In silico analysis of alpha-synuclein protein variants and posttranslational modifications related to Parkinson's disease.
J Cell Biochem
; 125(3): e30523, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38239037
4.
Altered hippocampal doublecortin expression in Parkinson's disease.
J Neurochem
; 2024 Mar 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38485468
5.
Chemical synthesis of site-selective advanced glycation end products in α-synuclein and its fragments.
Org Biomol Chem
; 22(13): 2670-2676, 2024 03 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-38483440
6.
Glycation modulates alpha-synuclein fibrillization kinetics: A sweet spot for inhibition.
J Biol Chem
; 298(5): 101848, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35314196
7.
PrP meets alpha-synuclein: Molecular mechanisms and implications for disease.
J Neurochem
; 2023 Oct 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37855859
8.
Is it all the RAGE? Defining the role of the receptor for advanced glycation end products in Parkinson's disease.
J Neurochem
; 2023 Jun 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-37381043
9.
Increased alpha-synuclein and neuroinflammation in the substantia nigra triggered by systemic inflammation are reversed by targeted inhibition of the receptor for advanced glycation end products (RAGE).
J Neurochem
; 2023 Sep 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-37661637
10.
The alpha-synuclein oligomers activate nuclear factor of activated T-cell (NFAT) modulating synaptic homeostasis and apoptosis.
Mol Med
; 29(1): 111, 2023 08 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37596531
11.
More than meets the eye in Parkinson's disease and other synucleinopathies: from proteinopathy to lipidopathy.
Acta Neuropathol
; 146(3): 369-385, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37421475
12.
Chemical Synthesis of Alpha-Synuclein Proteins via Solid-Phase Peptide Synthesis and Native Chemical Ligation.
Chemistry
; 29(33): e202300649, 2023 Jun 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-36971510
13.
Type 2 Diabetes and Parkinson's Disease: A Focused Review of Current Concepts.
Mov Disord
; 38(2): 162-177, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36567671
14.
Changes in α-Synuclein Posttranslational Modifications in an AAV-Based Mouse Model of Parkinson's Disease.
Int J Mol Sci
; 24(17)2023 Aug 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-37686236
15.
Beyond Motor Deficits: Environmental Enrichment Mitigates Huntington's Disease Effects in YAC128 Mice.
Int J Mol Sci
; 24(16)2023 Aug 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37628801
16.
The courage to change science.
EMBO Rep
; 21(3): e50124, 2020 03 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32077198
17.
Characterization of the activity, aggregation, and toxicity of heterodimers of WT and ALS-associated mutant Sod1.
Proc Natl Acad Sci U S A
; 116(51): 25991-26000, 2019 12 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-31796595
18.
Doxycycline inhibits α-synuclein-associated pathologies in vitro and in vivo.
Neurobiol Dis
; 151: 105256, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33429042
19.
Hsp27 reduces glycation-induced toxicity and aggregation of alpha-synuclein.
FASEB J
; 34(5): 6718-6728, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32259355
20.
Small molecule inhibits α-synuclein aggregation, disrupts amyloid fibrils, and prevents degeneration of dopaminergic neurons.
Proc Natl Acad Sci U S A
; 115(41): 10481-10486, 2018 10 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30249646