Detalhe da pesquisa
1.
The PxIxIT motif of the RCAN3 inhibits angiogenesis and tumor progression in Triple Negative breast cancer in immunocompetent mice.
Carcinogenesis
; 43(8): 808-812, 2022 09 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-35640493
2.
A novel role for an RCAN3-derived peptide as a tumor suppressor in breast cancer.
Carcinogenesis
; 36(7): 792-9, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25916653
3.
RCAN 1 and 3 proteins regulate thymic positive selection.
Biochem Biophys Res Commun
; 460(2): 295-301, 2015 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25783055
4.
Protein kinase CK2-dependent phosphorylation of the human Regulators of Calcineurin reveals a novel mechanism regulating the calcineurin-NFATc signaling pathway.
Biochim Biophys Acta
; 1833(10): 2311-21, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23732701
5.
Design and synthesis of a novel non peptide CN-NFATc signaling inhibitor for tumor suppression in triple negative breast cancer.
Eur J Med Chem
; 238: 114514, 2022 Aug 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35700596
6.
Intragraft expression of the IL-10 gene is up-regulated in renal protocol biopsies with early interstitial fibrosis, tubular atrophy, and subclinical rejection.
Am J Pathol
; 176(4): 1696-704, 2010 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-20150436
7.
A fluorescent polarization-based assay for the identification of disruptors of the RCAN1-calcineurin A protein complex.
Anal Biochem
; 398(1): 99-103, 2010 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19891949
8.
Seminal plasma microRNAs improve diagnosis/prognosis of prostate cancer in men with moderately altered prostate-specific antigen.
Am J Transl Res
; 12(5): 2041-2051, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32509198
9.
Cis-trans proline isomers in the catalytic domain of calcineurin.
FEBS J
; 286(6): 1230-1239, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30536857
10.
RCAN3, a novel calcineurin inhibitor that down-regulates NFAT-dependent cytokine gene expression.
Biochim Biophys Acta
; 1773(3): 330-41, 2007 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-17270291
11.
Functional characterization of twelve natural PROS1 mutations associated with anticoagulant protein S deficiency.
Haematologica
; 93(4): 574-80, 2008 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-18322254
12.
Functional characterization of the calcipressin 1 motif that suppresses calcineurin-mediated NFAT-dependent cytokine gene expression in human T cells.
Cell Signal
; 18(9): 1430-8, 2006 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-16406492
13.
Phosphorylation of calcipressin 1 increases its ability to inhibit calcineurin and decreases calcipressin half-life.
Biochem J
; 374(Pt 2): 567-75, 2003 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-12809556
14.
Calcineurin Undergoes a Conformational Switch Evoked via Peptidyl-Prolyl Isomerization.
PLoS One
; 10(8): e0134569, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26248042
15.
Identification of small-molecule inhibitors of calcineurin-NFATc signaling that mimic the PxIxIT motif of calcineurin binding partners.
Sci Signal
; 8(382): ra63, 2015 Jun 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-26106221
16.
Dyrk1A expression pattern supports specific roles of this kinase in the adult central nervous system.
Brain Res
; 964(2): 250-63, 2003 Feb 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-12576186
17.
The vertebrate RCAN gene family: novel insights into evolution, structure and regulation.
PLoS One
; 9(1): e85539, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24465593
18.
Renaming the DSCR1/Adapt78 gene family as RCAN: regulators of calcineurin.
FASEB J
; 21(12): 3023-8, 2007 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-17595344
19.
Inhibiting the calcineurin-NFAT (nuclear factor of activated T cells) signaling pathway with a regulator of calcineurin-derived peptide without affecting general calcineurin phosphatase activity.
J Biol Chem
; 284(14): 9394-401, 2009 Apr 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-19189965