Detalhe da pesquisa
1.
S-nitrosoglutathione induces ciliary neurotrophic factor expression in astrocytes, which has implications to protect the central nervous system under pathological conditions.
J Biol Chem
; 288(6): 3831-43, 2013 Feb 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-23264628
2.
AMP-activated protein kinase signaling protects oligodendrocytes that restore central nervous system functions in an experimental autoimmune encephalomyelitis model.
Am J Pathol
; 183(2): 526-41, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23759513
3.
Modulation of Rho-Rock signaling pathway protects oligodendrocytes against cytokine toxicity via PPAR-α-dependent mechanism.
Glia
; 61(9): 1500-1517, 2013 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-23839981
4.
Interference with RhoA-ROCK signaling mechanism in autoreactive CD4+ T cells enhances the bioavailability of 1,25-dihydroxyvitamin D3 in experimental autoimmune encephalomyelitis.
Am J Pathol
; 181(3): 993-1006, 2012 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-22796435
5.
Synergistic activity of interleukin-17 and tumor necrosis factor-α enhances oxidative stress-mediated oligodendrocyte apoptosis.
J Neurochem
; 116(4): 508-21, 2011 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-21143599
6.
Activation of PPAR-γ and PTEN cascade participates in lovastatin-mediated accelerated differentiation of oligodendrocyte progenitor cells.
Glia
; 58(14): 1669-85, 2010 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20578043
7.
Combination therapy of lovastatin and rolipram provides neuroprotection and promotes neurorepair in inflammatory demyelination model of multiple sclerosis.
Glia
; 57(2): 182-93, 2009 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18720408
8.
Modulation of peroxisome proliferator-activated receptor-alpha activity by N-acetyl cysteine attenuates inhibition of oligodendrocyte development in lipopolysaccharide stimulated mixed glial cultures.
J Neurochem
; 105(3): 956-70, 2008 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-18205750
9.
Attenuation of lipopolysaccharide-induced inflammatory response and phospholipids metabolism at the feto-maternal interface by N-acetyl cysteine.
Pediatr Res
; 64(4): 334-9, 2008 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-18552708
10.
HMG-CoA reductase inhibitor augments survival and differentiation of oligodendrocyte progenitors in animal model of multiple sclerosis.
FASEB J
; 19(11): 1407-21, 2005 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-16126908
11.
Impaired peroxisomal function in the central nervous system with inflammatory disease of experimental autoimmune encephalomyelitis animals and protection by lovastatin treatment.
Brain Res
; 1022(1-2): 1-11, 2004 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15353207
12.
Combinatorial Effect of Metformin and Lovastatin Impedes T-cell Autoimmunity and Neurodegeneration in Experimental Autoimmune Encephalomyelitis.
J Clin Cell Immunol
; 42013 Jun 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-24324917
13.
Increased Plp1 gene expression leads to massive microglial cell activation and inflammation throughout the brain.
ASN Neuro
; 2(4): e00043, 2010 Sep 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-20885931
14.
Combined medication of lovastatin with rolipram suppresses severity of experimental autoimmune encephalomyelitis.
Exp Neurol
; 214(2): 168-80, 2008 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-18775426
15.
Lipopolysaccharide-induced peroxisomal dysfunction exacerbates cerebral white matter injury: attenuation by N-acetyl cysteine.
Exp Neurol
; 210(2): 560-76, 2008 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-18291369
16.
Immunomodulatory effect of combination therapy with lovastatin and 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside alleviates neurodegeneration in experimental autoimmune encephalomyelitis.
Am J Pathol
; 169(3): 1012-25, 2006 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-16936274
17.
IL-4-induced peroxisome proliferator-activated receptor gamma activation inhibits NF-kappaB trans activation in central nervous system (CNS) glial cells and protects oligodendrocyte progenitors under neuroinflammatory disease conditions: implication for CNS-demyelinating diseases.
J Immunol
; 176(7): 4385-98, 2006 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16547277
18.
Molecular organization of peroxisomal enzymes: protein-protein interactions in the membrane and in the matrix.
Arch Biochem Biophys
; 451(2): 128-40, 2006 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16781659
19.
N-acetylcysteine prevents endotoxin-induced degeneration of oligodendrocyte progenitors and hypomyelination in developing rat brain.
J Neurosci Res
; 78(3): 347-61, 2004 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15389835