Detalhe da pesquisa
1.
HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials.
Lancet
; 385(9965): 351-61, 2015 Jan 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-25262344
2.
Use of allele-specific FAIRE to determine functional regulatory polymorphism using large-scale genotyping arrays.
PLoS Genet
; 8(8): e1002908, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22916038
3.
Abdominal aortic aneurysm is associated with a variant in low-density lipoprotein receptor-related protein 1.
Am J Hum Genet
; 89(5): 619-27, 2011 Nov 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-22055160
4.
Influence of common genetic variation on blood lipid levels, cardiovascular risk, and coronary events in two British prospective cohort studies.
Eur Heart J
; 34(13): 972-81, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-22977227
5.
The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis.
Lancet
; 379(9822): 1214-24, 2012 Mar 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-22421340
6.
Comparative analysis of genome-wide association studies signals for lipids, diabetes, and coronary heart disease: Cardiovascular Biomarker Genetics Collaboration.
Eur Heart J
; 33(3): 393-407, 2012 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-21804106
7.
Application of statistical and functional methodologies for the investigation of genetic determinants of coronary heart disease biomarkers: lipoprotein lipase genotype and plasma triglycerides as an exemplar.
Hum Mol Genet
; 19(20): 3936-47, 2010 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20650961
8.
Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
Am J Hum Genet
; 85(5): 628-42, 2009 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-19913121
9.
PLA2G7 genotype, lipoprotein-associated phospholipase A2 activity, and coronary heart disease risk in 10 494 cases and 15 624 controls of European Ancestry.
Circulation
; 121(21): 2284-93, 2010 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20479152
10.
Integrated associations of genotypes with multiple blood biomarkers linked to coronary heart disease risk.
Hum Mol Genet
; 18(12): 2305-16, 2009 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19336475
11.
Genetic variants associated with Von Willebrand factor levels in healthy men and women identified using the HumanCVD BeadChip.
Ann Hum Genet
; 75(4): 456-67, 2011 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-21534939
12.
Novel Insights Into the Effects of Interleukin 6 Antagonism in Non-ST-Segment-Elevation Myocardial Infarction Employing the SOMAscan Proteomics Platform.
J Am Heart Assoc
; 9(12): e015628, 2020 06 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-32515246
13.
The functional interaction on in vitro gene expression of APOA5 SNPs, defining haplotype APOA52, and their paradoxical association with plasma triglyceride but not plasma apoAV levels.
Biochim Biophys Acta
; 1782(7-8): 447-52, 2008.
Artigo
em Inglês
| MEDLINE | ID: mdl-18395529
14.
ANGPTL4 E40K and T266M: effects on plasma triglyceride and HDL levels, postprandial responses, and CHD risk.
Arterioscler Thromb Vasc Biol
; 28(12): 2319-25, 2008 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-18974381
15.
Plasma heat shock protein 60 and cardiovascular disease risk: the role of psychosocial, genetic, and biological factors.
Cell Stress Chaperones
; 12(4): 384-92, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-18229457
16.
Is the influence of variation in the ACE gene on the prospective risk of Type 2 diabetes in middle-aged men modified by obesity?
Clin Sci (Lond)
; 113(12): 467-72, 2007 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-17624939
17.
Common variants in the TCF7L2 gene and predisposition to type 2 diabetes in UK European Whites, Indian Asians and Afro-Caribbean men and women.
J Mol Med (Berl)
; 84(12): 1005-14, 2006 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-17665514
18.
Functional Analysis of the Coronary Heart Disease Risk Locus on Chromosome 21q22.
Dis Markers
; 2017: 1096916, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28458444
19.
Identification of the Functional Variant(s) that Explain the Low-Density Lipoprotein Receptor (LDLR) GWAS SNP rs6511720 Association with Lower LDL-C and Risk of CHD.
PLoS One
; 11(12): e0167676, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27973560
20.
Post-GWAS methodologies for localisation of functional non-coding variants: ANGPTL3.
Atherosclerosis
; 246: 193-201, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26800306