Detalhe da pesquisa
1.
Biophysical library screening using a Thermo-FMN assay to identify and characterize Clostridioides difficile FabK inhibitors.
Biochem Biophys Res Commun
; 705: 149740, 2024 Apr 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38458032
2.
A variant ECE1 allele contributes to reduced pathogenicity of Candida albicans during vulvovaginal candidiasis.
PLoS Pathog
; 17(9): e1009884, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34506615
3.
Species-Specific Differences in C-5 Sterol Desaturase Function Influence the Outcome of Azole Antifungal Exposure.
Antimicrob Agents Chemother
; 65(12): e0104421, 2021 11 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-34516249
4.
Loss of C-5 Sterol Desaturase Activity in Candida albicans: Azole Resistance or Merely Trailing Growth?
Antimicrob Agents Chemother
; 63(1)2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30323044
5.
Abrogation of Triazole Resistance upon Deletion of CDR1 in a Clinical Isolate of Candida auris.
Antimicrob Agents Chemother
; 63(4)2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30718246
6.
A Systematic Screen Reveals a Diverse Collection of Medications That Induce Antifungal Resistance in Candida Species.
Antimicrob Agents Chemother
; 63(5)2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30858206
7.
Comparative Analysis of the Capacity of the Candida Species To Elicit Vaginal Immunopathology.
Infect Immun
; 86(12)2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30249743
8.
Candidalysin Drives Epithelial Signaling, Neutrophil Recruitment, and Immunopathology at the Vaginal Mucosa.
Infect Immun
; 86(2)2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29109176
9.
Commonly Used Oncology Drugs Decrease Antifungal Effectiveness against Candida and Aspergillus Species.
Antimicrob Agents Chemother
; 62(7)2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29712657
10.
Overexpression of Candida albicans Secreted Aspartyl Proteinase 2 or 5 Is Not Sufficient for Exacerbation of Immunopathology in a Murine Model of Vaginitis.
Infect Immun
; 85(10)2017 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-28760935
11.
An Azole-Tolerant Endosomal Trafficking Mutant of Candida albicans Is Susceptible to Azole Treatment in a Mouse Model of Vaginal Candidiasis.
Antimicrob Agents Chemother
; 61(6)2017 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28348159
12.
Loss of C-5 Sterol Desaturase Activity Results in Increased Resistance to Azole and Echinocandin Antifungals in a Clinical Isolate of Candida parapsilosis.
Antimicrob Agents Chemother
; 61(9)2017 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28630186
13.
Endosomal Trafficking Defects Can Induce Calcium-Dependent Azole Tolerance in Candida albicans.
Antimicrob Agents Chemother
; 60(12): 7170-7177, 2016 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27645241
14.
ERG2 and ERG24 Are Required for Normal Vacuolar Physiology as Well as Candida albicans Pathogenicity in a Murine Model of Disseminated but Not Vaginal Candidiasis.
Eukaryot Cell
; 14(10): 1006-16, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26231054
15.
Trafficking through the late endosome significantly impacts Candida albicans tolerance of the azole antifungals.
Antimicrob Agents Chemother
; 59(4): 2410-20, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25666149
16.
Morphogenesis is not required for Candida albicans-Staphylococcus aureus intra-abdominal infection-mediated dissemination and lethal sepsis.
Infect Immun
; 82(8): 3426-35, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24891104
17.
Fungal morphogenetic pathways are required for the hallmark inflammatory response during Candida albicans vaginitis.
Infect Immun
; 82(2): 532-43, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24478069
18.
Vaginal epithelial cell-derived S100 alarmins induced by Candida albicans via pattern recognition receptor interactions are sufficient but not necessary for the acute neutrophil response during experimental vaginal candidiasis.
Infect Immun
; 82(2): 783-92, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24478092
19.
Synthesis and antifungal activity of substituted 2,4,6-pyrimidinetrione carbaldehyde hydrazones.
Bioorg Med Chem
; 22(2): 813-26, 2014 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24361188
20.
Three prevacuolar compartment Rab GTPases impact Candida albicans hyphal growth.
Eukaryot Cell
; 12(7): 1039-50, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-23709183