Detalhe da pesquisa
1.
4,4-Difluoroproline as a Unique 19F NMR Probe of Proline Conformation.
Biochemistry
; 63(9): 1131-1146, 2024 May 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-38598681
2.
Development of a Highly Responsive Organofluorine Temperature Sensor for 19F Magnetic Resonance Applications.
Anal Chem
; 94(9): 3782-3790, 2022 03 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35191677
3.
Upregulation of cytokine signalling in platelets increases risk of thrombophilia in severe COVID-19 patients.
Blood Cells Mol Dis
; 94: 102653, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35180460
4.
Diabetes mellitus, maternal adiposity, and insulin-dependent gestational diabetes are associated with COVID-19 in pregnancy: the INTERCOVID study.
Am J Obstet Gynecol
; 227(1): 74.e1-74.e16, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34942154
5.
Fluorescence Lifetime Measurement of Prefibrillar Sickle Hemoglobin Oligomers as a Platform for Drug Discovery in Sickle Cell Disease.
Biomacromolecules
; 23(9): 3822-3830, 2022 09 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35944154
6.
Selective N-Terminal BET Bromodomain Inhibitors by Targeting Non-Conserved Residues and Structured Water Displacement*.
Angew Chem Int Ed Engl
; 60(3): 1220-1226, 2021 01 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-32975004
7.
Electronic and Steric Control of nâπ* Interactions: Stabilization of the α-Helix Conformation without a Hydrogen Bond.
Chembiochem
; 20(7): 963-967, 2019 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30548564
8.
4R- and 4S-iodophenyl hydroxyproline, 4R-pentynoyl hydroxyproline, and S-propargyl-4-thiolphenylalanine: conformationally biased and tunable amino acids for bioorthogonal reactions.
Org Biomol Chem
; 14(7): 2327-46, 2016 Feb 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-26806113
9.
Tunable control of polyproline helix (PPII) structure via aromatic electronic effects: an electronic switch of polyproline helix.
Biochemistry
; 53(32): 5307-14, 2014 Aug 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-25075447
10.
OGlcNAcylation and phosphorylation have opposing structural effects in tau: phosphothreonine induces particular conformational order.
J Am Chem Soc
; 136(10): 3803-16, 2014 Mar 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-24559475
11.
(2S,4R)-4-hydroxyproline(4-nitrobenzoate): strong induction of stereoelectronic effects via a readily synthesized proline derivative. Crystallographic observation of a correlation between torsion angle and bond length in a hyperconjugative interaction.
J Org Chem
; 79(9): 4174-9, 2014 May 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-24720652
12.
Production of the PET bone agent (18)F-fluoride ion, simultaneously with (18)F-FDG by a single run of the medical cyclotron with minimal radiation exposure- a novel technique.
Hell J Nucl Med
; 17(2): 106-10, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25097896
13.
Proline editing: a general and practical approach to the synthesis of functionally and structurally diverse peptides. Analysis of steric versus stereoelectronic effects of 4-substituted prolines on conformation within peptides.
J Am Chem Soc
; 135(11): 4333-63, 2013 Mar 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-23402492
14.
pH Effects Can Dominate Chemical Shift Perturbations in 1H,15N-HSQC NMR Spectroscopy for Studies of Small Molecule/α-Synuclein Interactions.
ACS Chem Neurosci
; 14(4): 800-808, 2023 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36749138
15.
An Inherent Difference between Serine and Threonine Phosphorylation: Phosphothreonine Strongly Prefers a Highly Ordered, Compact, Cyclic Conformation.
ACS Chem Biol
; 18(9): 1938-1958, 2023 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37595155
16.
Clinical and experimental evidence suggest omicron variant of SARS-CoV-2 is inherently less pathogenic than delta variant independent of previous immunity.
Eur J Med Res
; 28(1): 421, 2023 Oct 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37821945
17.
Automated Detection of Poor-Quality Scintigraphic Images Using Machine Learning.
World J Nucl Med
; 21(4): 276-282, 2022 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-36398299
18.
Threonine Cavities Are Targetable Motifs That Control Alpha-Synuclein Fibril Growth.
ACS Chem Neurosci
; 13(17): 2646-2657, 2022 09 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36001084
19.
Sub-optimal neutralisation of omicron (B.1.1.529) variant by antibodies induced by vaccine alone or SARS-CoV-2 Infection plus vaccine (hybrid immunity) post 6-months.
EBioMedicine
; 78: 103938, 2022 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-35305396
20.
Inactivated whole-virion vaccine BBV152/Covaxin elicits robust cellular immune memory to SARS-CoV-2 and variants of concern.
Nat Microbiol
; 7(7): 974-985, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35681012