Detalhe da pesquisa
1.
Blockade of sodiumcalcium exchanger via ORM-10962 attenuates cardiac alternans.
J Mol Cell Cardiol
; 153: 111-122, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33383036
2.
Muscarinic agonists inhibit the ATP-dependent potassium current and suppress the ventricle-Purkinje action potential dispersion.
Can J Physiol Pharmacol
; 99(2): 247-253, 2021 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-33242286
3.
The Novel Inodilator ORM-3819 Relaxes Isolated Porcine Coronary Arteries: Role of Voltage-Gated Potassium Channel Activation.
J Cardiovasc Pharmacol
; 74(3): 218-224, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31356552
4.
Long-term endurance training-induced cardiac adaptation in new rabbit and dog animal models of the human athlete's heart.
Rev Cardiovasc Med
; 19(4): 135-142, 2018 Dec 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-31064165
5.
Different electrophysiological effects of the levo- and dextro-rotatory isomers of mexiletine in isolated rabbit cardiac muscle.
Can J Physiol Pharmacol
; 95(7): 830-836, 2017 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-28226224
6.
Long-term pretreatment with desethylamiodarone (DEA) or amiodarone (AMIO) protects against coronary artery occlusion induced ventricular arrhythmias in conscious rats.
Can J Physiol Pharmacol
; 93(9): 773-7, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-26176275
7.
Short-term beat-to-beat variability of the QT interval is increased and correlates with parameters of left ventricular hypertrophy in patients with hypertrophic cardiomyopathy.
Can J Physiol Pharmacol
; 93(9): 765-72, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-26313025
8.
Identification and functional characterisation of a novel KCNJ2 mutation, Val302del, causing Andersen-Tawil syndrome.
Can J Physiol Pharmacol
; 93(7): 569-75, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-26103554
9.
Assessment of efficacy of proarrhythmia biomarkers in isolated rabbit hearts with attenuated repolarization reserve.
J Cardiovasc Pharmacol
; 64(3): 266-76, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-24887684
10.
Ionic mechanisms limiting cardiac repolarization reserve in humans compared to dogs.
J Physiol
; 591(17): 4189-206, 2013 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23878377
11.
[Ca²âº] i-induced augmentation of the inward rectifier potassium current (IK1) in canine and human ventricular myocardium.
Pflugers Arch
; 465(11): 1621-35, 2013 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-23807312
12.
Altered expression of genes for Kir ion channels in dilated cardiomyopathy.
Can J Physiol Pharmacol
; 91(8): 648-56, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23889090
13.
The reverse mode of the Na+/Ca2+ exchanger contributes to the pacemaker mechanism in rabbit sinus node cells.
Sci Rep
; 12(1): 21830, 2022 12 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-36528651
14.
The development of L-type Ca2+ current mediated alternans does not depend on the restitution slope in canine ventricular myocardium.
Sci Rep
; 11(1): 16652, 2021 08 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-34404848
15.
Long-Term Endurance Exercise Training Alters Repolarization in a New Rabbit Athlete's Heart Model.
Front Physiol
; 12: 741317, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-35237176
16.
Increased Ca2+ content of the sarcoplasmic reticulum provides arrhythmogenic trigger source in swimming-induced rat athlete's heart model.
Sci Rep
; 10(1): 19596, 2020 11 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33177643
17.
Discovery and characterization of ORM-11372, a novel inhibitor of the sodium-calcium exchanger with positive inotropic activity.
Br J Pharmacol
; 177(24): 5534-5554, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32959887
18.
Does small-conductance calcium-activated potassium channel contribute to cardiac repolarization?
J Mol Cell Cardiol
; 47(5): 656-63, 2009 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-19632238
19.
The Na+/Ca2+ exchange blocker SEA0400 fails to enhance cytosolic Ca2+ transient and contractility in canine ventricular cardiomyocytes.
Cardiovasc Res
; 78(3): 476-84, 2008 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18252759
20.
Novel Na+/Ca2+ Exchanger Inhibitor ORM-10962 Supports Coupled Function of Funny-Current and Na+/Ca2+ Exchanger in Pacemaking of Rabbit Sinus Node Tissue.
Front Pharmacol
; 10: 1632, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-32063850