Detalhe da pesquisa
1.
Atezolizumab for Advanced Alveolar Soft Part Sarcoma.
N Engl J Med
; 389(10): 911-921, 2023 Sep 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37672694
2.
Combination therapy with pazopanib and tivantinib modulates VEGF and c-MET levels in refractory advanced solid tumors.
Invest New Drugs
; 39(6): 1577-1586, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34180036
3.
Compressing drug development timelines in oncology using phase '0' trials.
Nat Rev Cancer
; 7(2): 131-9, 2007 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-17251919
4.
Validation of a hypoxia-inducible factor-1 alpha specimen collection procedure and quantitative enzyme-linked immunosorbent assay in solid tumor tissues.
Anal Biochem
; 459: 1-11, 2014 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24799347
5.
Association of changes in expression of HDAC and SIRT genes after drug treatment with cancer cell line sensitivity to kinase inhibitors.
Epigenetics
; 19(1): 2309824, 2024 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-38369747
6.
Pharmacodynamic effects of the PARP inhibitor talazoparib (MDV3800, BMN 673) in patients with BRCA-mutated advanced solid tumors.
Cancer Chemother Pharmacol
; 93(3): 177-189, 2024 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38010394
7.
ERK signaling promotes resistance to TRK kinase inhibition in NTRK fusion-driven glioma mouse models.
bioRxiv
; 2024 Mar 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-38558981
8.
Redox phospholipidomics discovers pro-ferroptotic death signals in A375 melanoma cells in vitro and in vivo.
Redox Biol
; 61: 102650, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36870109
9.
Advances in using PARP inhibitors to treat cancer.
BMC Med
; 10: 25, 2012 Mar 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-22401667
10.
PARP Inhibitor Applicability: Detailed Assays for Homologous Recombination Repair Pathway Components.
Onco Targets Ther
; 15: 165-180, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35237050
11.
Loss of ubiquitin-specific peptidase 18 destabilizes 14-3-3ζ protein and represses lung cancer metastasis.
Cancer Biol Ther
; 23(1): 265-280, 2022 12 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-35387560
12.
A phase 1 and pharmacodynamic study of chronically-dosed, single-agent veliparib (ABT-888) in patients with BRCA1- or BRCA2-mutated cancer or platinum-refractory ovarian or triple-negative breast cancer.
Cancer Chemother Pharmacol
; 89(5): 721-735, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35435472
13.
ATR inhibition reverses the resistance of homologous recombination deficient MGMTlow/MMRproficient cancer cells to temozolomide.
Oncotarget
; 12(21): 2114-2130, 2021 Oct 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34676045
14.
Isoform- and Phosphorylation-specific Multiplexed Quantitative Pharmacodynamics of Drugs Targeting PI3K and MAPK Signaling in Xenograft Models and Clinical Biopsies.
Mol Cancer Ther
; 20(4): 749-760, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33536190
15.
Safety, Antitumor Activity, and Biomarker Analysis in a Phase I Trial of the Once-daily Wee1 Inhibitor Adavosertib (AZD1775) in Patients with Advanced Solid Tumors.
Clin Cancer Res
; 27(14): 3834-3844, 2021 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33863809
16.
The statistics of phase 0 trials.
Stat Med
; 29(10): 1072-6, 2010 May 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-20419759
17.
Phase I trial of TRC102 (methoxyamine HCl) in combination with temozolomide in patients with relapsed solid tumors and lymphomas.
Oncotarget
; 11(44): 3959-3971, 2020 Nov 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33216844
18.
Intravenous 5-fluoro-2'-deoxycytidine administered with tetrahydrouridine increases the proportion of p16-expressing circulating tumor cells in patients with advanced solid tumors.
Cancer Chemother Pharmacol
; 85(5): 979-993, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32314030
19.
Clinical Evolution of Epithelial-Mesenchymal Transition in Human Carcinomas.
Cancer Res
; 80(2): 304-318, 2020 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31732654
20.
Synergistic antitumor activity of oncolytic reovirus and chemotherapeutic agents in non-small cell lung cancer cells.
Mol Cancer
; 8: 47, 2009 Jul 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-19594950