RESUMO
A dog from western Newfoundland was presented with paradoxical vestibular syndrome. First-stage larvae of Angiostrongylus vasorum were detected on fecal examination. Treatment with milbemycin oxime resulted in resolution of signs. This is the first report of the spread of this parasite to western Newfoundland and of paradoxical vestibular syndrome in a dog infected with A. vasorum.
Syndrome vestibulaire paradoxal chez un chien de l'ouest de Terre-Neuve infecté par des vers du cÅur(Angiostrongylus vasorum). Un chien de l'ouest de Terre-Neuve a été présenté avec un syndrome vestibulaire paradoxal. Des larves de premier stade d'Angiostrongylus vasorum ont été détectées à l'examen fécal. Le traitement à l'aide d'oxime de milbémycine a produit une disparition des symptômes. Il s'agit du premier rapport de la propagation de ce parasite dans l'ouest de Terre-Neuve et du syndrome vestibulaire paradoxal chez un chien infecté par A. vasorum.(Traduit par Isabelle Vallières).
Assuntos
Angiostrongylus/isolamento & purificação , Doenças do Cão/parasitologia , Infecções por Strongylida/veterinária , Doenças Vestibulares/veterinária , Aminas/administração & dosagem , Aminas/uso terapêutico , Analgésicos/administração & dosagem , Analgésicos/uso terapêutico , Animais , Anti-Helmínticos/administração & dosagem , Anti-Helmínticos/uso terapêutico , Ácidos Cicloexanocarboxílicos/administração & dosagem , Ácidos Cicloexanocarboxílicos/uso terapêutico , Dexametasona/administração & dosagem , Dexametasona/uso terapêutico , Difenidramina/administração & dosagem , Difenidramina/uso terapêutico , Doenças do Cão/epidemiologia , Cães , Gabapentina , Antagonistas dos Receptores Histamínicos/administração & dosagem , Antagonistas dos Receptores Histamínicos/uso terapêutico , Imunossupressores/administração & dosagem , Imunossupressores/uso terapêutico , Macrolídeos/administração & dosagem , Macrolídeos/uso terapêutico , Masculino , Terra Nova e Labrador/epidemiologia , Infecções por Strongylida/tratamento farmacológico , Infecções por Strongylida/epidemiologia , Infecções por Strongylida/parasitologia , Doenças Vestibulares/tratamento farmacológico , Doenças Vestibulares/etiologia , Ácido gama-Aminobutírico/administração & dosagem , Ácido gama-Aminobutírico/uso terapêuticoRESUMO
One spayed female Labrador retriever and two castrated male golden retrievers were evaluated for chronic (i.e., ranging from 3 wk to 24 wk) neurologic signs localizable to the prosencephalon. Signs included seizures, circling, and behavior changes. MRI demonstrated extra-axial, contrast-enhancing, multiloculated, fluid-filled, cyst-like lesions with a mass effect, causing compression and displacement of brain parenchyma. Differential diagnoses included cystic neoplasm, abscess or other infectious cyst (e.g., alveolar hydatid cyst), or fluid-filled anomaly (e.g., arachnoid cyst). The cyst-like lesions were attached to the rostral falx cerebri in all cases. In addition, case 2 had a second polycystic mass at the caudal diencephalon. Surgical biopsy (case 3 with a single, rostral tumor via transfrontal craniectomy) and postmortem histology (in cases 1 and 2) confirmed polycystic meningiomas. Tumor types were transitional (cases 1 and 3) and fibrous (case 2), with positive immunohistochemical staining for vimentin. Case 3 was also positive for E-cadherin, s100, and CD34. In all cases, staining was predominantly negative for glial fibrillary acid protein and pancytokeratins, supporting a diagnosis of meningioma. This report describes the first cases of polycystic meningiomas in dogs. Polycystic meningiomas are a rare, but important, addition to the differential diagnoses for intracranial cyst-like lesions, significantly affecting planning for surgical resection and other therapeutic interventions.
Assuntos
Cistos/veterinária , Doenças do Cão/diagnóstico , Imageamento por Ressonância Magnética/veterinária , Neoplasias Meníngeas/veterinária , Meningioma/veterinária , Animais , Cistos/diagnóstico , Cistos/cirurgia , Diagnóstico Diferencial , Doenças do Cão/cirurgia , Cães , Evolução Fatal , Feminino , Masculino , Neoplasias Meníngeas/diagnóstico , Neoplasias Meníngeas/cirurgia , Meningioma/diagnóstico , Meningioma/cirurgiaRESUMO
OBJECTIVE: To compare electroencephalography (EEG) artifact associated with use of the subdermal wire electrode (SWE), gold cup electrode (GCE), and subdermal needle electrode (SNE) over an 8-hour period in sedated and awake dogs. ANIMALS: 6 healthy dogs. PROCEDURES: 8 EEG channels were recorded during 20-minute video-EEG recording sessions (intermittently at 0.5, 2, 4, 6, and 8 hours) with and without chlorpromazine sedation. Nonphysiologic artifacts were identified. Duration of artifact was summed for each channel. Number of unaffected channels (NUC) was determined. RESULTS: NUC was significantly affected by electrode type and sedation over time; median for SWE (2.80 channels; 95% confidence interval [CI], 0.84 to 5.70 channels) was significantly different from medians for GCE (7.87 channels; 95% CI, 7.44 to 7.94 channels) and SNE (7.60 channels; 95% CI, 6.61 to 7.89 channels). After 4 hours, NUC decreased in awake dogs, regardless of electrode type. In awake dogs, duration of artifact differed significantly between SWE and GCE or SNE; medians at 8 hours were 61.55 seconds (95% CI, 21.81 to 173.65 seconds), 1.33 seconds (95% CI, 0.47 to 3.75 seconds), and 21.01 seconds (95% CI, 6.85 to 64.42 seconds), respectively. CONCLUSIONS AND CLINICAL RELEVANCE: The SWE had a significant duration of artifact during recording periods > 2 hours, compared with results for the GCE and SNE, in awake dogs. The GCE, SNE, and sedation resulted in significantly more channels unaffected by artifact. For longer recordings, caution should be exercised in selecting EEG electrodes and sedation state, although differences among electrodes may not be clinically relevant.
Assuntos
Anestesia/veterinária , Cães , Eletroencefalografia/veterinária , Anestesia/métodos , Animais , Artefatos , Clorpromazina/farmacologia , Eletrodos , Eletrodos Implantados , Eletroencefalografia/instrumentação , Eletroencefalografia/métodos , Feminino , Fatores de TempoRESUMO
OBJECTIVE: To establish the incidence of and risk factors for seizures following myelography performed with iohexol in dogs. DESIGN: Retrospective case series. ANIMALS: 503 dogs. PROCEDURES: Medical records were searched for dogs that underwent myelography between April 2002 and December 2004. Data extracted included body weight, breed, age, sex, volume and dose of iohexol, site of injections, location of lesion, duration of anesthesia, surgical procedures immediately after myelography, use of acepromazine, and presence or absence of seizures. RESULTS: 15 (3%) dogs had postmyelographic seizures. Risk factors significantly associated with seizures were size of dogs (large dogs were 35.35 times as likely to have seizures as were small dogs), location of contrast medium injection (dogs in which iohexol was injected into the cerebellomedullary cistern were 7.4 times as likely to have seizures as were dogs in which iohexol was injected into the lumbar cistern), location of lesion (dogs with lesions at the level of the cervical portion of the vertebral column were 4.65 times as likely to develop seizures as were dogs with lesions in other regions), and total volume of iohexol. Mean ± SD total volume of iohexol was 11.73 ± 5.52 mL (median, 10.5 mL [range, 3.0 to 21.0 mL]) for dogs that had seizures and 4.57 ± 4.13 mL (median, 3.5 mL [range, 0.75 to 45.0 mL]) for those that did not. CONCLUSIONS AND CLINICAL RELEVANCE: Large-breed dogs with cervical lesions and large volumes of iohexol injected into the cerebellomedullary cistern had the highest risk of seizures. The use of contrast medium volumes > 8 mL in large dogs should be avoided, with preference given to injections into the lumbar cistern.
Assuntos
Meios de Contraste/efeitos adversos , Doenças do Cão/induzido quimicamente , Iohexol/efeitos adversos , Mielografia/veterinária , Convulsões/veterinária , Animais , Meios de Contraste/farmacologia , Cães , Feminino , Alucinações , Iohexol/farmacologia , Masculino , Mielografia/efeitos adversos , Estudos Retrospectivos , Fatores de Risco , Convulsões/induzido quimicamenteRESUMO
OBJECTIVE: To compare outcomes and survival times for dogs with cervical spondylomyelopathy (CSM; wobbler syndrome) treated medically or surgically. DESIGN: Retrospective case series. ANIMALS: 104 dogs. PROCEDURES: Medical records of dogs were included if the diagnosis of CSM had been made on the basis of results of diagnostic imaging and follow-up information (minimum, 6 months) was available. Ordinal logistic regression was used to compare outcomes and the product-limit method was used to compare survival times between dogs treated surgically and dogs treated medically. RESULTS: 37 dogs were treated surgically, and 67 were treated medically. Owners reported that 30 (81%) dogs treated surgically were improved, 1 (3%) was unchanged, and 6 (16%) were worse and that 36 (54%) dogs treated medically were improved, 18 (27%) were unchanged, and 13 (19%) were worse. Outcome was not significantly different between groups. Information on survival time was available for 33 dogs treated surgically and 43 dogs treated medically. Forty of the 76 (53%) dogs were euthanized because of CSM. Median and mean survival times were 36 and 48 months, respectively, for dogs treated medically and 36 and 46.5 months, respectively, for dogs treated surgically. Survival times did not differ significantly between groups. CONCLUSIONS AND CLINICAL RELEVANCE: In the present study, neither outcome nor survival time was significantly different between dogs with CSM treated medically and dogs treated surgically, suggesting that medical treatment is a viable and valuable option for management of dogs with CSM.
Assuntos
Vértebras Cervicais/patologia , Descompressão Cirúrgica/veterinária , Doenças do Cão/cirurgia , Doenças do Cão/terapia , Compressão da Medula Espinal/veterinária , Animais , Descompressão Cirúrgica/métodos , Cães , Feminino , Modelos Logísticos , Masculino , Exame Neurológico/veterinária , Estudos Retrospectivos , Compressão da Medula Espinal/cirurgia , Compressão da Medula Espinal/terapia , Taxa de Sobrevida , Resultado do TratamentoRESUMO
Ultrasound-guided fine needle aspiration was used in establishing the diagnosis in 4 cases of malignant peripheral nerve sheath tumor. Sonographic and cytologic characteristics are discussed. Because of its availability and ease of use, axillary ultrasonography with fine needle aspiration can be an initial diagnostic step for suspected brachial plexus tumors.
Assuntos
Biópsia por Agulha Fina/veterinária , Doenças do Cão/patologia , Neoplasias de Bainha Neural/veterinária , Ultrassonografia/veterinária , Animais , Biópsia por Agulha Fina/métodos , Diagnóstico Diferencial , Doenças do Cão/diagnóstico por imagem , Cães , Feminino , Masculino , Neoplasias de Bainha Neural/diagnóstico por imagem , Neoplasias de Bainha Neural/patologia , Sensibilidade e Especificidade , Ultrassonografia/métodosRESUMO
OBJECTIVE: To evaluate progression of clinical signs and magnetic resonance imaging (MRI) findings in dogs with cervical spondylomyelopathy (wobbler syndrome) treated medically or surgically. DESIGN: Prospective cohort study. ANIMALS: 12 Doberman Pinschers. PROCEDURES: Neurologic examinations and MRI were performed before medical (n = 9) or surgical treatment (ventral slot, 3) and a minimum of 12 months later. RESULTS: Mean follow-up time was 14.5 months. Clinically, 2 dogs improved after surgical treatment and 5 improved after medical treatment. Magnetic resonance imaging of surgically treated dogs revealed adequate spinal cord decompression. Spinal cord signal changes were seen in 2 dogs before surgery, both of which had new signal changes at the same and adjacent sites during follow-up examination. One dog treated surgically developed 3 new areas of spinal cord compression. In the medically treated dogs, the severity of spinal cord compression at the time of follow-up examination was unchanged in 4 dogs, worse in 2 dogs, and improved in 3 dogs, but spinal cord atrophy was observed on transverse images. Four medically treated dogs had changes in spinal cord signal initially, but none developed new signal changes or compressions. CONCLUSIONS AND CLINICAL RELEVANCE: Medical and surgical treatment improved or stabilized the clinical condition of most dogs. Surgical treatment appeared to hasten the development of additional areas of spinal cord compression and lesions in dogs with preoperative cord changes; however, the clinical importance of these changes was not determined. The progression of pathologic MRI abnormalities was notably less in medically treated dogs, compared with surgically treated dogs.
Assuntos
Vértebras Cervicais/patologia , Doenças do Cão/diagnóstico , Imageamento por Ressonância Magnética/veterinária , Compressão da Medula Espinal/veterinária , Animais , Estudos de Coortes , Descompressão Cirúrgica/métodos , Descompressão Cirúrgica/veterinária , Progressão da Doença , Doenças do Cão/tratamento farmacológico , Doenças do Cão/cirurgia , Cães , Feminino , Seguimentos , Processamento de Imagem Assistida por Computador , Imageamento por Ressonância Magnética/métodos , Masculino , Exame Neurológico/veterinária , Estudos Prospectivos , Compressão da Medula Espinal/diagnóstico , Compressão da Medula Espinal/tratamento farmacológico , Compressão da Medula Espinal/cirurgia , Fatores de Tempo , Resultado do TratamentoRESUMO
OBJECTIVE: To compare morphologic and morphometric features of the cervical vertebral column and spinal cord of Doberman Pinschers with and without clinical signs of cervical spondylomyelopathy (CSM; wobbler syndrome) detected via magnetic resonance imaging (MRI). ANIMALS: 16 clinically normal and 16 CSM-affected Doberman Pinschers. PROCEDURES: For each dog, MRI of the cervical vertebral column (in neutral and traction positions) was performed. Morphologically, MRI abnormalities were classified according to a spinal cord compression scale. Foraminal stenosis and intervertebral disk degeneration and protrusion were also recorded. Morphometric measurements of the vertebral canal and spinal cord were obtained in sagittal and transverse MRI planes. RESULTS: 4 of 16 clinically normal and 15 of 16 CSM-affected dogs had spinal cord compression. Twelve clinically normal and all CSM-affected dogs had disk degeneration. Foraminal stenosis was detected in 11 clinically normal and 14 CSM-affected dogs. Vertebral canal and spinal cord areas were consistently smaller in CSM-affected dogs, compared with clinically normal dogs. In neutral and traction positions, the intervertebral disks of CSM-affected dogs were wider than those of clinically normal dogs but the amount of disk distraction was similar between groups. CONCLUSIONS AND CLINICAL RELEVANCE: The incidence of intervertebral disk degeneration and foraminal stenosis in clinically normal Doberman Pinschers was high; cervical spinal cord compression may be present without concurrent clinical signs. A combination of static factors (ie, a relatively stenotic vertebral canal and wider intervertebral disks) distinguished CSM-affected dogs from clinically normal dogs and appears to be a key feature in the pathogenesis of CSM.
Assuntos
Doenças do Cão/diagnóstico , Cães/anatomia & histologia , Imageamento por Ressonância Magnética/veterinária , Compressão da Medula Espinal/veterinária , Animais , Vértebras Cervicais/patologia , Feminino , Processamento de Imagem Assistida por Computador , Masculino , Estudos Prospectivos , Análise de Regressão , Compressão da Medula Espinal/diagnóstico , Estenose Espinal/patologia , Estenose Espinal/veterináriaRESUMO
OBJECTIVE: To establish the reference ranges for motor evoked potential (MEP) latency and amplitude in clinically normal Doberman Pinschers, compare the MEPs of Doberman Pinschers with and without clinical signs of cervical spondylomyelopathy (CSM; wobbler syndrome), and determine whether MEP data correlate with neurologic or magnetic resonance imaging (MRI) findings. ANIMALS: 16 clinically normal and 16 CSM-affected Doberman Pinschers. PROCEDURES: Dogs were classified according to their neurologic deficits. After sedation with acepromazine and hydromorphone, transcranial magnetic MEPs were assessed in each dog; latencies and amplitudes were recorded from the extensor carpi radialis and cranial tibial muscles. Magnetic resonance imaging was performed to evaluate the presence and severity of spinal cord compression. RESULTS: Significant differences in cranial tibial muscle MEP latencies and amplitudes were detected between clinically normal and CSM-affected dogs. No differences in the extensor carpi radialis MEP were detected between groups. There was a significant correlation (r = 0.776) between the cranial tibial muscle MEP latencies and neurologic findings. Significant correlations were also found between MRI findings and the cranial tibial muscle MEP latencies (r = 0.757) and amplitudes (r = -0.453). CONCLUSIONS AND CLINICAL RELEVANCE: Results provided a reference range for MEPs in clinically normal Doberman Pinschers and indicated that cranial tibial muscle MEP latencies correlated well with both MRI and neurologic findings. Because of the high correlation between cranial tibial muscle MEP data and neurologic and MRI findings, MEP assessment could be considered as a screening tool in the management of dogs with spinal cord disease.
Assuntos
Vértebras Cervicais/fisiopatologia , Doenças do Cão/fisiopatologia , Cães/fisiologia , Potencial Evocado Motor/fisiologia , Compressão da Medula Espinal/veterinária , Animais , Doenças do Cão/patologia , Cães/anatomia & histologia , Feminino , Imageamento por Ressonância Magnética/veterinária , Masculino , Estudos Prospectivos , Compressão da Medula Espinal/patologia , Compressão da Medula Espinal/fisiopatologia , Estimulação Magnética Transcraniana/veterináriaRESUMO
OBJECTIVE: To evaluate use of transcranial magnetic motor evoked potentials for assessment of the functional integrity of the cervical spinal cord in large-breed dogs with cervical spinal cord disease. DESIGN: Randomized, controlled, masked study. ANIMALS: 10 healthy large-breed control dogs and 25 large-breed dogs with cervical spinal cord diseases. PROCEDURE: Affected dogs were allocated to 3 groups on the basis of neurologic status: signs of neck pain alone, ambulatory with ataxia in all limbs, or nonambulatory. Transcranial magnetic stimulation was performed on each dog with the same standard technique. Motor evoked potentials (MEP) were recorded from electrodes inserted in the tibialis cranialis muscle. Following the procedure, each dog was anesthetized and cervical radiography, CSF analysis, and cervical myelography were performed. The MEP latencies and amplitudes were correlated with neurologic status of the dogs after correction for neuronal path length. RESULTS: Mean MEP latencies and amplitudes were significantly different between control dogs and dogs in each of the 3 neurologic categories, but were not significantly different among dogs in the 3 neurologic categories. A linear association was evident between MEP latencies and amplitudes and severity of neurologic deficits; the more severe the neurologic deficits, the more prolonged the latencies and the more decreased the amplitudes. CONCLUSIONS AND CLINICAL RELEVANCE: Transcranial magnetic MEP are useful to assess severity of cervical spinal cord disease in large-breed dogs. Impairment of the functional integrity of the cervical spinal cord was found even in dogs with neck pain alone.
Assuntos
Doenças do Cão/diagnóstico , Potencial Evocado Motor , Doenças da Medula Espinal/veterinária , Animais , Ataxia/fisiopatologia , Ataxia/veterinária , Vértebras Cervicais , Doenças do Cão/fisiopatologia , Cães , Estimulação Elétrica , Campos Eletromagnéticos , Eletromiografia/veterinária , Feminino , Masculino , Músculos do Pescoço/fisiopatologia , Exame Neurológico/veterinária , Índice de Gravidade de Doença , Doenças da Medula Espinal/diagnóstico , Doenças da Medula Espinal/fisiopatologiaRESUMO
OBJECTIVES: To evaluate a population of chondrodystrophic dogs treated for Hansen type 1 intervertebral disk (IVD) disease by surgical decompression with or without prophylactic fenestration and determine the rate and location of surgically confirmed recurrence of intervertebral disk extrusion. ANIMALS: 265 dogs. STUDY DESIGN: Retrospective study. PROCEDURES: Medical records of dogs that underwent spinal decompression between 1995 and 1999 were reviewed. RESULTS: 3 (4.9%) dogs were euthanatized or died prior to discharge. Fenestration was performed in 252 dogs, including 37 (14.7%) at the site of decompression only, 48 (19%) at 3 to 4 disk spaces, and 167 (66%) at 5 to 7 disk spaces. There were 12 instances of recurrent disk extrusion confirmed by removal of disk at a second surgery 3.5 to 33 months after the first surgery. Recurrence was always at a new disk space, and rates did not significantly differ between dogs that underwent single or multiple fenestrations. Two recurrences were at a previously fenestrated disk space. Seven recurrences were at a site immediately adjacent to a fenestrated disk space, and 5 recurrences were at L4-5. CONCLUSIONS AND CLINICAL RELEVANCE: Prophylactic fenestration is generally successful in preventing future disk extrusions at fenestrated disk spaces. Prospective evaluation is still required to determine whether fenestration decreases the overall rate of recurrence. Prophylactic fenestration could promote disk extrusion at adjacent, nonfenestrated disk spaces. This could have a substantial clinical impact if recurrence develops at L4-5.
Assuntos
Descompressão Cirúrgica/veterinária , Doenças do Cão/cirurgia , Deslocamento do Disco Intervertebral/veterinária , Vértebras Lombares , Osteocondrodisplasias/veterinária , Vértebras Torácicas , Animais , Descompressão Cirúrgica/métodos , Cães/anatomia & histologia , Feminino , Deslocamento do Disco Intervertebral/cirurgia , Vértebras Lombares/cirurgia , Masculino , Osteocondrodisplasias/complicações , Recidiva , Estudos Retrospectivos , Vértebras Torácicas/cirurgia , Resultado do TratamentoRESUMO
An 11-year-old male Pekingese was evaluated because of a history of head tilt. Neurologic examination revealed a right-sided head tilt, ataxia, scoliosis, and proprioceptive deficits. Diagnostic testing included magnetic resonance imaging (MRI) of the head and neck. After IV administration of gadopentetate dimeglumine, an extra-axial, highly contrast-enhanced mass in the brainstem, cerebellar herniation, and syringohydromyelia were detected via MRI. The dog was treated with corticosteroids and radiation therapy of the mass for 4 weeks (total dose, 42.5 Gy). Magnetic resonance imaging was repeated 9 weeks and 6 months after radiation therapy; compared with the initial findings, a reduction in the size of the brainstem mass was observed in both MRI scans. The third MRI scan also revealed a normal cerebellar shape, no evidence of herniation, and resolution of syringohydromyelia in the dog at that time. It is recommended that whenever syringohydromyelia is observed via MRI, a primary cause (cranial or caudal to the affected region) should be sought.
Assuntos
Neoplasias do Tronco Encefálico/veterinária , Doenças do Cão/diagnóstico , Siringomielia/veterinária , Corticosteroides/uso terapêutico , Animais , Neoplasias do Tronco Encefálico/complicações , Neoplasias do Tronco Encefálico/radioterapia , Cerebelo/patologia , Fossa Craniana Posterior/patologia , Doenças do Cão/patologia , Doenças do Cão/radioterapia , Cães , Imageamento por Ressonância Magnética/veterinária , Masculino , Siringomielia/etiologia , Resultado do TratamentoRESUMO
OBJECTIVE: To evaluate interobserver agreement and diagnostic accuracy of brain MRI in dogs. DESIGN: Evaluation study. ANIMALS: 44 dogs. PROCEDURES: 5 board-certified veterinary radiologists with variable MRI experience interpreted transverse T2-weighted (T2w), T2w fluid-attenuated inversion recovery (FLAIR), and T1-weighted-FLAIR; transverse, sagittal, and dorsal T2w; and T1-weighted-FLAIR postcontrast brain sequences (1.5 T). Several imaging parameters were scored, including the following: lesion (present or absent), lesion characteristics (axial localization, mass effect, edema, hemorrhage, and cavitation), contrast enhancement characteristics, and most likely diagnosis (normal, neoplastic, inflammatory, vascular, metabolic or toxic, or other). Magnetic resonance imaging diagnoses were determined initially without patient information and then repeated, providing history and signalment. For all cases and readers, MRI diagnoses were compared with final diagnoses established with results from histologic examination (when available) or with other pertinent clinical data (CSF analysis, clinical response to treatment, or MRI follow-up). Magnetic resonance scores were compared between examiners with κ statistics. RESULTS: Reading agreement was substantial to almost perfect (0.64 < κ < 0.86) when identifying a brain lesion on MRI; fair to moderate (0.14 < κ < 0.60) when interpreting hemorrhage, edema, and pattern of contrast enhancement; fair to substantial (0.22 < κ < 0.74) for dural tail sign and categorization of margins of enhancement; and moderate to substantial (0.40 < κ < 0.78) for axial localization, presence of mass effect, cavitation, intensity, and distribution of enhancement. Interobserver agreement was moderate to substantial for categories of diagnosis (0.56 < κ < 0.69), and agreement with the final diagnosis was substantial regardless of whether patient information was (0.65 < κ < 0.76) or was not (0.65 < κ < 0.68) provided. CONCLUSIONS AND CLINICAL RELEVANCE: The present study found that whereas some MRI features such as edema and hemorrhage were interpreted less consistently, radiologists were reasonably constant and accurate when providing diagnoses.