Detalhe da pesquisa
1.
Cooperativity between Cas9 and hyperactive AID establishes broad and diversifying mutational footprints in base editors.
Nucleic Acids Res
; 52(4): 2078-2090, 2024 Feb 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-38261989
2.
Efficient engineering of human and mouse primary cells using peptide-assisted genome editing.
Nat Biotechnol
; 42(2): 305-315, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-37095348
3.
Action and timing of BacC and BacD in the late stages of biosynthesis of the dipeptide antibiotic bacilysin.
Biochemistry
; 52(5): 889-901, 2013 Feb 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-23317005
4.
Enzymatic capture of an extrahelical thymine in the search for uracil in DNA.
Nature
; 449(7161): 433-7, 2007 Sep 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-17704764
5.
Stereochemical outcome at four stereogenic centers during conversion of prephenate to tetrahydrotyrosine by BacABGF in the bacilysin pathway.
Biochemistry
; 51(28): 5622-32, 2012 Jul 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-22765234
6.
Olefin isomerization regiochemistries during tandem action of BacA and BacB on prephenate in bacilysin biosynthesis.
Biochemistry
; 51(15): 3241-51, 2012 Apr 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-22483065
7.
Dynamics of uracil and 5-fluorouracil in DNA.
Biochemistry
; 50(5): 612-7, 2011 Feb 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-21190322
8.
Effect of the thymidylate synthase inhibitors on dUTP and TTP pool levels and the activities of DNA repair glycosylases on uracil and 5-fluorouracil in DNA.
Biochemistry
; 50(5): 618-27, 2011 Feb 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-21222484
9.
Impact of linker strain and flexibility in the design of a fragment-based inhibitor.
Nat Chem Biol
; 5(6): 407-13, 2009 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-19396178
10.
Uracil DNA glycosylase: revisiting substrate-assisted catalysis by DNA phosphate anions.
Biochemistry
; 47(33): 8614-22, 2008 Aug 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-18652484