Detalhe da pesquisa
1.
Is genetic variability in carboxylesterase-1 and carboxylesterase-2 drug metabolism an important component of personalized medicine?
Xenobiotica
; 50(1): 92-100, 2020 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-31601149
2.
Inhibition of carboxylesterase-1 alters clopidogrel metabolism and disposition.
Xenobiotica
; 50(3): 245-251, 2020 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-31039046
3.
Alterations of drug-metabolizing enzymes and transporters under diabetic conditions: what is the potential clinical significance?
Drug Metab Rev
; 50(3): 369-397, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30221555
4.
Comparison of caffeine disposition following administration by oral solution (energy drink) and inspired powder (AeroShot) in human subjects.
Br J Clin Pharmacol
; 83(12): 2687-2694, 2017 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-28758694
5.
Measurement of caffeine and its three primary metabolites in human plasma by HPLC-ESI-MS/MS and clinical application.
Biomed Chromatogr
; 31(6)2017 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-27864843
6.
Identification of carboxylesterase-dependent dabigatran etexilate hydrolysis.
Drug Metab Dispos
; 42(2): 201-6, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24212379
7.
Identification of alcohol-dependent clopidogrel metabolites using conventional liquid chromatography/triple quadrupole mass spectrometry.
Rapid Commun Mass Spectrom
; 28(11): 1285-92, 2014 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24760569
8.
Conventional liquid chromatography/triple quadrupole mass spectrometry based metabolite identification and semi-quantitative estimation approach in the investigation of in vitro dabigatran etexilate metabolism.
Anal Bioanal Chem
; 405(5): 1695-704, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23239178
9.
In vivo information-guided prediction approach for assessing the risks of drug-drug interactions associated with circulating inhibitory metabolites.
Drug Metab Dispos
; 40(8): 1487-94, 2012 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-22563046
10.
Carboxylesterase-2 plays a critical role in dabigatran etexilate active metabolite formation.
Drug Metab Pharmacokinet
; 47: 100479, 2022 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-36375226
11.
Alcohol inhibits the metabolism of dimethyl fumarate to the active metabolite responsible for decreasing relapse frequency in the treatment of multiple sclerosis.
PLoS One
; 17(11): e0278111, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36441753
12.
The effect of ethanol on oral cocaine pharmacokinetics reveals an unrecognized class of ethanol-mediated drug interactions.
Drug Metab Dispos
; 38(2): 317-22, 2010 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-19920055
13.
Pharmacodynamic evaluation of the cardiovascular effects after the coadministration of cocaine and ethanol.
Drug Metab Dispos
; 37(2): 310-4, 2009 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-19005030
14.
Clinical implications of genetic variation in carboxylesterase drug metabolism.
Expert Opin Drug Metab Toxicol
; 14(2): 131-142, 2018 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-29264996
15.
Student Pharmacists' Perceptions of a Composite Examination in Their First Professional Year.
Am J Pharm Educ
; 80(1): 4, 2016 Feb 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-26941430
16.
The Importance of Research and Scholarly Activity in Pharmacy Training.
Pharmacotherapy
; 36(12): e200-e205, 2016 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27885711
17.
Safety, Pharmacokinetics, and Pharmacodynamics of a Humanized Anti-Semaphorin 4D Antibody, in a First-In-Human Study of Patients with Advanced Solid Tumors.
Clin Cancer Res
; 22(4): 827-36, 2016 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26446947
18.
Effects of alcohol on human carboxylesterase drug metabolism.
Clin Pharmacokinet
; 54(6): 627-38, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-25511794
19.
Stroke associated with discontinuation of warfarin therapy for atrial fibrillation.
Curr Med Res Opin
; 31(11): 2021-9, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26390258
20.
Discontinuation/Interruption of Warfarin Therapy in Patients with Nonvalvular Atrial Fibrillation.
J Manag Care Spec Pharm
; 21(7): 596-606, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-26108384