Detalhe da pesquisa
1.
A single dose of self-transcribing and replicating RNA-based SARS-CoV-2 vaccine produces protective adaptive immunity in mice.
Mol Ther
; 29(6): 1970-1983, 2021 06 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33823303
2.
Genotoxicity and carcinogenicity risk assessment of prucalopride, a selective 5-hydroxytryptamine 4 receptor agonist.
Regul Toxicol Pharmacol
; 112: 104586, 2020 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-31972188
3.
Current strategies in the non-clinical safety assessment of biologics: New targets, new molecules, new challenges.
Regul Toxicol Pharmacol
; 98: 98-107, 2018 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-30026135
4.
Workshop Proceedings: Streamlined Development of Safety Assessment Programs Supporting Orphan/Rare Diseases-Are We There Yet?
Int J Toxicol
; 35(4): 393-409, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27272885
5.
Microscopic background changes in brains of cynomolgus monkeys.
Toxicol Pathol
; 43(4): 513-8, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24935239
6.
Safety, immunogenicity and efficacy of the self-amplifying mRNA ARCT-154 COVID-19 vaccine: pooled phase 1, 2, 3a and 3b randomized, controlled trials.
Nat Commun
; 15(1): 4081, 2024 May 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38744844
7.
In vivo pharmacology and toxicology evaluation of polyethylene glycol-conjugated interferon beta-1a.
J Pharmacol Exp Ther
; 338(3): 984-96, 2011 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-21690216
8.
Carcinogenicity assessments of biotechnology-derived pharmaceuticals: a review of approved molecules and best practice recommendations.
Toxicol Pathol
; 38(4): 522-53, 2010 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-20472697
9.
Safety, tolerability, and lack of antibody responses after administration of a PfCSP DNA malaria vaccine via needle or needle-free jet injection, and comparison of intramuscular and combination intramuscular/intradermal routes.
Hum Gene Ther
; 13(13): 1551-60, 2002 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-12228010
10.
Immunotoxicity profile of natalizumab.
J Immunotoxicol
; 6(2): 115-29, 2009 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-19589098
11.
The development of a bicistronic plasmid DNA vaccine for B-cell lymphoma.
Vaccine
; 20(9-10): 1400-11, 2002 Jan 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-11818159