Detalhe da pesquisa
1.
5-Aza-4'-thio-2'-deoxycytidine, a New Orally Bioavailable Nontoxic "Best-in-Class": DNA Methyltransferase 1-Depleting Agent in Clinical Development.
J Pharmacol Exp Ther
; 379(3): 211-222, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34503994
2.
6-Methylpurine derived sugar modified nucleosides: Synthesis and evaluation of their substrate activity with purine nucleoside phosphorylases.
Bioorg Chem
; 65: 9-16, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26745284
3.
PRE-CLINICAL AND CLINICAL VALIDATION OF AN ANTI-CANCER MODALITY THAT ABLATES REFRACTORY, LOW GROWTH FRACTION TUMORS.
Trans Am Clin Climatol Assoc
; 127: 59-70, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-28066038
4.
Role of methylthioadenosine/S-adenosylhomocysteine nucleosidase in Vibrio cholerae cellular communication and biofilm development.
Biochem Biophys Res Commun
; 461(1): 65-9, 2015 May 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-25849889
5.
Deoxycytidine kinase regulates the G2/M checkpoint through interaction with cyclin-dependent kinase 1 in response to DNA damage.
Nucleic Acids Res
; 40(19): 9621-32, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22850745
6.
Effectiveness of disinfection therapies and promotion of osteoblast growth on osseotite and nanotite implant surfaces.
Implant Dent
; 23(4): 426-33, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24776940
7.
Evaluating antitumor activity of Escherichia coli purine nucleoside phosphorylase against head and neck patient-derived xenografts.
Cancer Rep (Hoboken)
; 6(2): e1708, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36253876
8.
Identification and characterization of two adenosine phosphorylase activities in Mycobacterium smegmatis.
J Bacteriol
; 193(20): 5668-74, 2011 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-21821769
9.
The crystal structure of Streptococcus pyogenes uridine phosphorylase reveals a distinct subfamily of nucleoside phosphorylases.
Biochemistry
; 50(30): 6549-58, 2011 Aug 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-21707079
10.
Structure of grouper iridovirus purine nucleoside phosphorylase.
Acta Crystallogr D Biol Crystallogr
; 66(Pt 2): 155-62, 2010 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-20124695
11.
The use of Trichomonas vaginalis purine nucleoside phosphorylase to activate fludarabine in the treatment of solid tumors.
Cancer Chemother Pharmacol
; 85(3): 573-583, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31915968
12.
Intratumoral generation of 2-fluoroadenine to treat solid malignancies of the head and neck.
Head Neck
; 41(6): 1979-1983, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30633420
13.
Synthesis of 1-beta-D-ribofuranosyl-3-ethynyl-[1,2,4]triazole and its in vitro and in vivo efficacy against Hantavirus.
Antiviral Res
; 79(1): 19-27, 2008 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-18394724
14.
c-Abl-independent p73 stabilization during gemcitabine- or 4'-thio-beta-D-arabinofuranosylcytosine-induced apoptosis in wild-type and p53-null colorectal cancer cells.
Mol Cancer Ther
; 5(2): 400-10, 2006 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-16505115
15.
Antiangiogenic activity of 4'-thio-beta-D-arabinofuranosylcytosine.
Mol Cancer Ther
; 5(9): 2218-24, 2006 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-16985055
16.
Use of E. coli Purine Nucleoside Phosphorylase in the Treatment of Solid Tumors.
Curr Pharm Des
; 2017 11 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29119917
17.
Structure-activity relationship for nucleoside analogs as inhibitors or substrates of adenosine kinase from Mycobacterium tuberculosis. I. Modifications to the adenine moiety.
Biochem Pharmacol
; 71(12): 1671-82, 2006 Jun 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-16620788
18.
Long intracellular retention of 4'-thio-arabinofuranosylcytosine 5'-triphosphate as a critical factor for the anti-solid tumor activity of 4'-thio-arabinofuranosylcytosine.
Cancer Chemother Pharmacol
; 57(6): 772-80, 2006 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-16180016
19.
Enzymology of purine and pyrimidine antimetabolites used in the treatment of cancer.
Chem Rev
; 109(7): 2880-93, 2009 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-19476376
20.
Excellent in vivo bystander activity of fludarabine phosphate against human glioma xenografts that express the escherichia coli purine nucleoside phosphorylase gene.
Cancer Res
; 64(18): 6610-5, 2004 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-15374975