Detalhe da pesquisa
1.
Two essential Thioredoxins mediate apicoplast biogenesis, protein import, and gene expression in Toxoplasma gondii.
PLoS Pathog
; 14(2): e1006836, 2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29470517
2.
Pharmacokinetics and In Vivo Efficacy of Pyrazolopyrimidine, Pyrrolopyrimidine, and 5-Aminopyrazole-4-Carboxamide Bumped Kinase Inhibitors against Toxoplasmosis.
J Infect Dis
; 219(9): 1464-1473, 2019 04 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-30423128
3.
Toxoplasma Calcium-Dependent Protein Kinase 1 Inhibitors: Probing Activity and Resistance Using Cellular Thermal Shift Assays.
Antimicrob Agents Chemother
; 62(6)2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29555627
4.
Extended-spectrum antiprotozoal bumped kinase inhibitors: A review.
Exp Parasitol
; 180: 71-83, 2017 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-28065755
5.
Integrative analysis of the Trypanosoma brucei gene expression cascade predicts differential regulation of mRNA processing and unusual control of ribosomal protein expression.
BMC Genomics
; 17: 306, 2016 Apr 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-27118143
6.
Genetic validation of aminoacyl-tRNA synthetases as drug targets in Trypanosoma brucei.
Eukaryot Cell
; 13(4): 504-16, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24562907
7.
Apicoplast targeting of a Toxoplasma gondii transmembrane protein requires a cytosolic tyrosine-based motif.
Traffic
; 13(5): 694-704, 2012 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-22288938
8.
Extensive stage-regulation of translation revealed by ribosome profiling of Trypanosoma brucei.
BMC Genomics
; 15: 911, 2014 Oct 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-25331479
9.
Enigmatic presence of mitochondrial complex I in Trypanosoma brucei bloodstream forms.
Eukaryot Cell
; 11(2): 183-93, 2012 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-22158713
10.
An essential Trypanosoma brucei protein kinase: a functional analysis of regulation and the identification of inhibitors.
Front Parasitol
; 22023.
Artigo
em Inglês
| MEDLINE | ID: mdl-38099268
11.
Benzoylbenzimidazole-based selective inhibitors targeting Cryptosporidium parvum and Toxoplasma gondii calcium-dependent protein kinase-1.
Bioorg Med Chem Lett
; 22(16): 5264-7, 2012 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22795629
12.
The Trypanosoma brucei life cycle switch TbPTP1 is structurally conserved and dephosphorylates the nucleolar protein NOPP44/46.
J Biol Chem
; 285(29): 22075-81, 2010 Jul 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-20444707
13.
A novel protein kinase localized to lipid droplets is required for droplet biogenesis in trypanosomes.
Eukaryot Cell
; 9(11): 1702-10, 2010 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-20833891
14.
Trypanosoma brucei: Two mitogen activated protein kinase kinases are dispensable for growth and virulence of the bloodstream form.
Exp Parasitol
; 128(3): 250-5, 2011 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-21396364
15.
Compartmentation prevents a lethal turbo-explosion of glycolysis in trypanosomes.
Proc Natl Acad Sci U S A
; 105(46): 17718-23, 2008 Nov 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-19008351
16.
Unusual features and localization of the membrane kinome of Trypanosoma brucei.
PLoS One
; 16(10): e0258814, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34653230
17.
Chromatin-Associated Protein Complexes Link DNA Base J and Transcription Termination in Leishmania.
mSphere
; 6(1)2021 02 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-33627513
18.
Widespread variation in transcript abundance within and across developmental stages of Trypanosoma brucei.
BMC Genomics
; 10: 482, 2009 Oct 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-19840382
19.
Evolving insights into protein trafficking to the multiple compartments of the apicomplexan plastid.
J Eukaryot Microbiol
; 56(3): 214-20, 2009.
Artigo
em Inglês
| MEDLINE | ID: mdl-19527348
20.
A thioredoxin family protein of the apicoplast periphery identifies abundant candidate transport vesicles in Toxoplasma gondii.
Eukaryot Cell
; 7(9): 1518-29, 2008 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-18586952