Detalhe da pesquisa
1.
Risk SNP-Mediated Promoter-Enhancer Switching Drives Prostate Cancer through lncRNA PCAT19.
Cell
; 174(3): 564-575.e18, 2018 07 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-30033362
2.
Unprocessed genomic uracil as a source of DNA replication stress in cancer cells.
Mol Cell
; 84(11): 2036-2052.e7, 2024 Jun 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38688279
3.
ATR inhibition induces synthetic lethality in mismatch repair-deficient cells and augments immunotherapy.
Genes Dev
; 37(19-20): 929-943, 2023 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37932012
4.
Nucleolar RNA polymerase II drives ribosome biogenesis.
Nature
; 585(7824): 298-302, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32669707
5.
Excessive transcription-replication conflicts are a vulnerability of BRCA1-mutant cancers.
Nucleic Acids Res
; 51(9): 4341-4362, 2023 05 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-36928661
6.
RNF8 ubiquitylation of XRN2 facilitates R-loop resolution and restrains genomic instability in BRCA1 mutant cells.
Nucleic Acids Res
; 51(19): 10484-10505, 2023 10 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-37697435
7.
APOBEC3A induces DNA gaps through PRIMPOL and confers gap-associated therapeutic vulnerability.
Sci Adv
; 10(3): eadk2771, 2024 Jan 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-38241374
8.
ATR protects ongoing and newly assembled DNA replication forks through distinct mechanisms.
Cell Rep
; 42(7): 112792, 2023 07 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37454295
9.
The RNA m5C modification in R-loops as an off switch of Alt-NHEJ.
Nat Commun
; 14(1): 6114, 2023 09 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-37777505
10.
Emerging roles of DNA topoisomerases in the regulation of R-loops.
Mutat Res Genet Toxicol Environ Mutagen
; 876-877: 503450, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35483781
11.
The metabolic enzyme hexokinase 2 localizes to the nucleus in AML and normal haematopoietic stem and progenitor cells to maintain stemness.
Nat Cell Biol
; 24(6): 872-884, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35668135
12.
BRCA1 and Metastasis: Outcome of Defective DNA Repair.
Cancers (Basel)
; 14(1)2021 Dec 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-35008272
13.
Exploiting synthetic lethality to target BRCA1/2-deficient tumors: where we stand.
Oncogene
; 40(17): 3001-3014, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33716297
14.
Strategic Training in Transdisciplinary Radiation Science for the 21st Century (STARS21): 15-Year Evaluation of an Innovative Research Training Program.
Int J Radiat Oncol Biol Phys
; 110(3): 656-666, 2021 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33440225
15.
RNF168 regulates R-loop resolution and genomic stability in BRCA1/2-deficient tumors.
J Clin Invest
; 131(3)2021 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33529165
16.
Preclinical evaluation of the selective small-molecule UBA1 inhibitor, TAK-243, in acute myeloid leukemia.
Leukemia
; 33(1): 37-51, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29884901
17.
Ubiquitin ligase RNF8 suppresses Notch signaling to regulate mammary development and tumorigenesis.
J Clin Invest
; 128(10): 4525-4542, 2018 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30222135
18.
Ubiquitin ligase RNF8 suppresses Notch signaling to regulate mammary development and tumorigenesis.
J Clin Invest
; 131(13)2021 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34196309