1.
Childs Nerv Syst
; 30(1): 47-64, 2014 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24193148
RESUMO
BACKGROUND: Most cancers of the central nervous system (CNS) occur sporadically in the absence of any known underlying familial disorder or multi-systemic syndrome. Several syndromes are associated with CNS malignancies, however, and their recognition has significant implications for patient management and prognosis. Patients with syndrome-associated CNS malignancies often have multiple tumours (either confined to one region or distributed throughout the body), with similar or different histology. OBJECTIVE: This review examines syndromes that are strongly associated with CNS cancers: the phakomatosis syndromes, familial syndromes such as Li-Fraumeni and familial polyposis syndromes and dyschondroplasia.
Assuntos
Neoplasias Encefálicas/diagnóstico , Neoplasias Encefálicas/terapia , Síndromes Neoplásicas Hereditárias/diagnóstico , Síndromes Neoplásicas Hereditárias/terapia , Animais , Neoplasias Encefálicas/genética , Humanos , Síndrome de Li-Fraumeni/diagnóstico , Síndrome de Li-Fraumeni/genética , Síndrome de Li-Fraumeni/terapia , Síndromes Neoplásicas Hereditárias/genética , Neurofibromatoses/diagnóstico , Neurofibromatoses/genética , Neurofibromatoses/terapia
2.
Can J Neurol Sci
; 38(2): 357-9, 2011 Mar.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21320848