Detalhe da pesquisa
1.
Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnel.
iScience
; 27(2): 108907, 2024 Feb 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38318365
2.
Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress.
Nat Cancer
; 3(2): 156-172, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35228749
3.
Computational and Experimental Druggability Assessment of Human DNA Glycosylases.
ACS Omega
; 4(7): 11642-11656, 2019 Jul 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-31460271
4.
Nucleobase and Nucleoside Analogues: Resistance and Re-Sensitisation at the Level of Pharmacokinetics, Pharmacodynamics and Metabolism.
Cancers (Basel)
; 10(7)2018 Jul 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-30041457
5.
Small-molecule inhibitor of OGG1 suppresses proinflammatory gene expression and inflammation.
Science
; 362(6416): 834-839, 2018 11 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-30442810
6.
With me or against me: Tumor suppressor and drug resistance activities of SAMHD1.
Exp Hematol
; 52: 32-39, 2017 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28502830
7.
SAMHD1 protects cancer cells from various nucleoside-based antimetabolites.
Cell Cycle
; 16(11): 1029-1038, 2017 Jun 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28436707
8.
dUTPase inhibition augments replication defects of 5-Fluorouracil.
Oncotarget
; 8(14): 23713-23726, 2017 Apr 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28423595
9.
Targeting SAMHD1 with the Vpx protein to improve cytarabine therapy for hematological malignancies.
Nat Med
; 23(2): 256-263, 2017 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-28067901