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1.
Int J Mol Sci ; 24(12)2023 Jun 18.
Artigo em Inglês | MEDLINE | ID: mdl-37373461

RESUMO

Bioresorbable nanomembranes (NMs) and nanoparticles (NPs) are powerful polymeric materials playing an important role in biomedicine, as they can effectively reduce infections and inflammatory clinical patient conditions due to their high biocompatibility, ability to physically interact with biomolecules, large surface area, and low toxicity. In this review, the most common bioabsorbable materials such as those belonging to natural polymers and proteins for the manufacture of NMs and NPs are reviewed. In addition to biocompatibility and bioresorption, current methodology on surface functionalization is also revisited and the most recent applications are highlighted. Considering the most recent use in the field of biosensors, tethered lipid bilayers, drug delivery, wound dressing, skin regeneration, targeted chemotherapy and imaging/diagnostics, functionalized NMs and NPs have become one of the main pillars of modern biomedical applications.


Assuntos
Implantes Absorvíveis , Nanopartículas , Humanos , Nanopartículas/uso terapêutico , Sistemas de Liberação de Medicamentos , Polímeros
2.
ACS Appl Bio Mater ; 6(5): 1720-1741, 2023 05 15.
Artigo em Inglês | MEDLINE | ID: mdl-37115912

RESUMO

Biosensors are increasingly taking a more active role in health science. The current needs for the constant monitoring of biomedical signals, as well as the growing spending on public health, make it necessary to search for materials with a combination of properties such as biocompatibility, electroactivity, resorption, and high selectivity to certain bioanalytes. Conducting polymer hydrogels seem to be a very promising materials, since they present many of the necessary properties to be used as biosensors. Furthermore, their properties can be shaped and enhanced by designing conductive polymer hydrogel-based composites with more specific functionalities depending on the end application. This work will review the recent state of the art of different biological hydrogels for biosensor applications, discuss the properties of the different components alone and in combination, and reveal their high potential as candidate materials in the fabrication of all-organic diagnostic, wearable, and implantable sensor devices.


Assuntos
Técnicas Biossensoriais , Dispositivos Eletrônicos Vestíveis , Polímeros , Hidrogéis , Próteses e Implantes
3.
Nanoscale ; 11(23): 11315-11321, 2019 Jun 21.
Artigo em Inglês | MEDLINE | ID: mdl-31165836

RESUMO

We describe the preparation of inverted white light emitting diodes by solution processing. The active layer is formed uniquely by Carbon Nanodots (C-dots) that display white-light emission at voltage close to 5 V when combined with metal oxides as charge transport layers. Moreover, we have demonstrated that the white light is not the product of charge transfer between the polymer selective contact and the C-dots but the result of the different recombination processes within the C-dots.

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