Detalhe da pesquisa
1.
Time course and magnitude of alpha-synuclein inclusion formation and nigrostriatal degeneration in the rat model of synucleinopathy triggered by intrastriatal α-synuclein preformed fibrils.
Neurobiol Dis
; 130: 104525, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31276792
2.
Subthalamic Nucleus Deep Brain Stimulation Employs trkB Signaling for Neuroprotection and Functional Restoration.
J Neurosci
; 37(28): 6786-6796, 2017 07 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-28607168
3.
Lewy body-like alpha-synuclein inclusions trigger reactive microgliosis prior to nigral degeneration.
J Neuroinflammation
; 15(1): 129, 2018 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29716614
4.
Correction to: Lewy body-like alpha-synuclein inclusions trigger reactive microgliosis prior to nigral degeneration.
J Neuroinflammation
; 15(1): 169, 2018 May 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-29843738
5.
Nortriptyline inhibits aggregation and neurotoxicity of alpha-synuclein by enhancing reconfiguration of the monomeric form.
Neurobiol Dis
; 106: 191-204, 2017 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-28711409
6.
Interrogating the aged striatum: robust survival of grafted dopamine neurons in aging rats produces inferior behavioral recovery and evidence of impaired integration.
Neurobiol Dis
; 77: 191-203, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25771169
7.
Intrastriatal injection of pre-formed mouse α-synuclein fibrils into rats triggers α-synuclein pathology and bilateral nigrostriatal degeneration.
Neurobiol Dis
; 82: 185-199, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26093169
8.
Inhibition of glucosylceramide synthase stimulates autophagy flux in neurons.
J Neurochem
; 129(5): 884-94, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24494600
9.
Tricyclic antidepressants delay the need for dopaminergic therapy in early Parkinson's disease.
Mov Disord
; 27(7): 880-7, 2012 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-22555881
10.
BDNF rs10501087, rs1491850 and rs11030094 polymorphisms associated with delayed progression in early-stage Parkinson's disease.
Front Neurol
; 13: 1053591, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36468063
11.
α-Synuclein antisense oligonucleotides as a disease-modifying therapy for Parkinson's disease.
JCI Insight
; 6(5)2021 03 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33682798
12.
3,4-Methylenedioxy-N-methamphetamine (ecstasy) promotes the survival of fetal dopamine neurons in culture.
Neuropharmacology
; 55(5): 851-9, 2008 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-18655796
13.
Bdnf variant is associated with milder motor symptom severity in early-stage Parkinson's disease.
Parkinsonism Relat Disord
; 53: 70-75, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29759928
14.
Spatial patterns of neuroimaging biomarker change in individuals from families with autosomal dominant Alzheimer's disease: a longitudinal study.
Lancet Neurol
; 17(3): 241-250, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29397305
15.
Increased cell suspension concentration augments the survival rate of grafted tyrosine hydroxylase immunoreactive neurons.
J Neurosci Methods
; 166(1): 13-9, 2007 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17706789
16.
Impact of age and vector construct on striatal and nigral transgene expression.
Mol Ther Methods Clin Dev
; 3: 16082, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27933309
17.
Tricyclic antidepressant treatment evokes regional changes in neurotrophic factors over time within the intact and degenerating nigrostriatal system.
Exp Neurol
; 266: 11-21, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25681575
18.
Chronic amitriptyline treatment attenuates nigrostriatal degeneration and significantly alters trophic support in a rat model of parkinsonism.
Neuropsychopharmacology
; 40(4): 874-83, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25267343
19.
Behavioral characterization of A53T mice reveals early and late stage deficits related to Parkinson's disease.
PLoS One
; 8(8): e70274, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23936403
20.
Transplantation of subventricular zone neural precursors induces an endogenous precursor cell response in a rat model of Parkinson's disease.
J Comp Neurol
; 515(1): 102-15, 2009 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19399899