Detalhe da pesquisa
1.
A host-directed oxadiazole compound potentiates antituberculosis treatment via zinc poisoning in human macrophages and in a mouse model of infection.
PLoS Biol
; 22(4): e3002259, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38683873
2.
Natural mutations in the sensor kinase of the PhoPR two-component regulatory system modulate virulence of ancestor-like tuberculosis bacilli.
PLoS Pathog
; 19(7): e1011437, 2023 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-37450466
3.
Mycobacterium abscessus virulence traits unraveled by transcriptomic profiling in amoeba and macrophages.
PLoS Pathog
; 15(11): e1008069, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31703112
4.
Key experimental evidence of chromosomal DNA transfer among selected tuberculosis-causing mycobacteria.
Proc Natl Acad Sci U S A
; 113(35): 9876-81, 2016 08 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-27528665
5.
CD4+ T Cells Recognizing PE/PPE Antigens Directly or via Cross Reactivity Are Protective against Pulmonary Mycobacterium tuberculosis Infection.
PLoS Pathog
; 12(7): e1005770, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27467705
6.
The changes in mycolic acid structures caused by hadC mutation have a dramatic effect on the virulence of Mycobacterium tuberculosis.
Mol Microbiol
; 99(4): 794-807, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26538472
7.
A new piperidinol derivative targeting mycolic acid transport in Mycobacterium abscessus.
Mol Microbiol
; 101(3): 515-29, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27121350
8.
Evolutionary history of tuberculosis shaped by conserved mutations in the PhoPR virulence regulator.
Proc Natl Acad Sci U S A
; 111(31): 11491-6, 2014 Aug 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-25049399
9.
A specific polymorphism in Mycobacterium tuberculosis H37Rv causes differential ESAT-6 expression and identifies WhiB6 as a novel ESX-1 component.
Infect Immun
; 82(8): 3446-56, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24891105
10.
Identification and characterization of the genetic changes responsible for the characteristic smooth-to-rough morphotype alterations of clinically persistent Mycobacterium abscessus.
Mol Microbiol
; 90(3): 612-29, 2013 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-23998761
11.
Genomic and phenotypic characterization of Mycobacterium tuberculosis' closest-related non-tuberculous mycobacteria.
Microbiol Spectr
; : e0412623, 2024 May 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38700329
12.
Overexpression of proinflammatory TLR-2-signalling lipoproteins in hypervirulent mycobacterial variants.
Cell Microbiol
; 13(5): 692-704, 2011 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-21143571
13.
A lentiviral vector encoding fusion of light invariant chain and mycobacterial antigens induces protective CD4+ T cell immunity.
Cell Rep
; 40(4): 111142, 2022 07 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-35905717
14.
A lentiviral vector expressing a dendritic cell-targeting multimer induces mucosal anti-mycobacterial CD4+ T-cell immunity.
Mucosal Immunol
; 15(6): 1389-1404, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36104497
15.
De novo synthesized polyunsaturated fatty acids operate as both host immunomodulators and nutrients for Mycobacterium tuberculosis.
Elife
; 102021 12 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-34951591
16.
Parallel in vivo experimental evolution reveals that increased stress resistance was key for the emergence of persistent tuberculosis bacilli.
Nat Microbiol
; 6(8): 1082-1093, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34294904
17.
Pathogenomic analyses of Mycobacterium microti, an ESX-1-deleted member of the Mycobacterium tuberculosis complex causing disease in various hosts.
Microb Genom
; 7(2)2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33529148
18.
TbD1 deletion as a driver of the evolutionary success of modern epidemic Mycobacterium tuberculosis lineages.
Nat Commun
; 11(1): 684, 2020 02 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32019932
19.
Changes in transcriptome after in vivo exposure to ionising radiation reveal a highly specialised liver response.
Int J Radiat Biol
; 85(8): 656-71, 2009 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-19637078
20.
Lsr2 Is an Important Determinant of Intracellular Growth and Virulence in Mycobacterium abscessus.
Front Microbiol
; 10: 905, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31114557