Detalhe da pesquisa
1.
Population genomics of the Viking world.
Nature
; 585(7825): 390-396, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32939067
2.
Ancient Human Genomes and Environmental DNA from the Cement Attaching 2,000-Year-Old Head Lice Nits.
Mol Biol Evol
; 39(2)2022 02 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34963129
3.
First-in-human trial exploring safety, antitumor activity, and pharmacokinetics of Sym013, a recombinant pan-HER antibody mixture, in advanced epithelial malignancies.
Invest New Drugs
; 40(3): 586-595, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35113285
4.
Postglacial viability and colonization in North America's ice-free corridor.
Nature
; 537(7618): 45-49, 2016 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27509852
5.
Author Correction: Population genomics of the Viking world.
Nature
; 591(7851): E29, 2021 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-33707634
6.
Sym004-induced EGFR elimination is associated with profound anti-tumor activity in EGFRvIII patient-derived glioblastoma models.
J Neurooncol
; 138(3): 489-498, 2018 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-29564747
7.
A combination of two antibodies recognizing non-overlapping epitopes of HER2 induces kinase activity-dependent internalization of HER2.
J Cell Mol Med
; 20(10): 1999-2011, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27469139
8.
Combination of two anti-CD5 monoclonal antibodies synergistically induces complement-dependent cytotoxicity of chronic lymphocytic leukaemia cells.
Br J Haematol
; 163(2): 182-93, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23927424
9.
Deep neural networks identify signaling mechanisms of ErbB-family drug resistance from a continuous cell morphology space.
Cell Rep
; 34(3): 108657, 2021 01 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-33472071
10.
Targeting of EGFR by a combination of antibodies mediates unconventional EGFR trafficking and degradation.
Sci Rep
; 10(1): 663, 2020 01 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-31959764
11.
Colorectal cancer residual disease at maximal response to EGFR blockade displays a druggable Paneth cell-like phenotype.
Sci Transl Med
; 12(555)2020 08 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32759276
12.
Sym021, a promising anti-PD1 clinical candidate antibody derived from a new chicken antibody discovery platform.
MAbs
; 11(4): 666-680, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31046547
13.
GLI1 is involved in cell cycle regulation and proliferation of NT2 embryonal carcinoma stem cells.
DNA Cell Biol
; 27(5): 251-6, 2008 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-18241033
14.
Efficacy of Sym004 in Patients With Metastatic Colorectal Cancer With Acquired Resistance to Anti-EGFR Therapy and Molecularly Selected by Circulating Tumor DNA Analyses: A Phase 2 Randomized Clinical Trial.
JAMA Oncol
; 4(4): e175245, 2018 Apr 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-29423521
15.
An ERBB1-3 Neutralizing Antibody Mixture With High Activity Against Drug-Resistant HER2+ Breast Cancers With ERBB Ligand Overexpression.
J Natl Cancer Inst
; 109(11)2017 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29059433
16.
Simultaneous Targeting of Two Distinct Epitopes on MET Effectively Inhibits MET- and HGF-Driven Tumor Growth by Multiple Mechanisms.
Mol Cancer Ther
; 16(12): 2780-2791, 2017 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-28802255
17.
Hedgehog signaling in small-cell lung cancer: frequent in vivo but a rare event in vitro.
Lung Cancer
; 52(3): 281-90, 2006 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-16616798
18.
Transcriptional gene expression profiling of small cell lung cancer cells.
Cancer Res
; 63(8): 1943-53, 2003 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-12702587
19.
Targeting Three Distinct HER2 Domains with a Recombinant Antibody Mixture Overcomes Trastuzumab Resistance.
Mol Cancer Ther
; 14(3): 669-80, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25612619
20.
Pan-HER, an Antibody Mixture Simultaneously Targeting EGFR, HER2, and HER3, Effectively Overcomes Tumor Heterogeneity and Plasticity.
Clin Cancer Res
; 21(18): 4110-22, 2015 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25908781