Detalhe da pesquisa
1.
Water Leakage Pathway Leads to Internal Hydration of the p53 Core Domain.
Biochemistry
; 62(1): 35-43, 2023 01 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36535020
2.
Loss of the p53 transactivation domain results in high amyloid aggregation of the Δ40p53 isoform in endometrial carcinoma cells.
J Biol Chem
; 294(24): 9430-9439, 2019 06 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-31028175
3.
Aggregation-primed molten globule conformers of the p53 core domain provide potential tools for studying p53C aggregation in cancer.
J Biol Chem
; 293(29): 11374-11387, 2018 07 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-29853637
4.
Distinct modulatory role of RNA in the aggregation of the tumor suppressor protein p53 core domain.
J Biol Chem
; 292(22): 9345-9357, 2017 06 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28420731
5.
Allosteric Transmission along a Loosely Structured Backbone Allows a Cardiac Troponin C Mutant to Function with Only One Ca2+ Ion.
J Biol Chem
; 292(6): 2379-2394, 2017 02 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28049727
6.
Phase separation of p53 precedes aggregation and is affected by oncogenic mutations and ligands.
Chem Sci
; 12(21): 7334-7349, 2021 Apr 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-34163823
7.
Oncogenic Gain of Function in Glioblastoma Is Linked to Mutant p53 Amyloid Oligomers.
iScience
; 23(2): 100820, 2020 Feb 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31981923
8.
The Status of p53 Oligomeric and Aggregation States in Cancer.
Biomolecules
; 10(4)2020 04 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32260447
9.
Aggregation tendencies in the p53 family are modulated by backbone hydrogen bonds.
Sci Rep
; 6: 32535, 2016 09 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27600721