Detalhe da pesquisa
1.
The Negative Allosteric Modulator EU1794-4 Reduces Single-Channel Conductance and Ca2+ Permeability of GluN1/GluN2A N-Methyl-d-Aspartate Receptors.
Mol Pharmacol
; 99(5): 399-411, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33688039
2.
[3 + 2]-Annulation of pyridinium ylides with 1-chloro-2-nitrostyrenes unveils a tubulin polymerization inhibitor.
Org Biomol Chem
; 19(33): 7234-7245, 2021 09 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34387294
3.
Synthesis and biological evaluation of 5'-C-methyl nucleotide prodrugs for treating HCV infections.
Bioorg Med Chem Lett
; 30(23): 127539, 2020 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32919013
4.
A Machine Learning Approach for Predicting HIV Reverse Transcriptase Mutation Susceptibility of Biologically Active Compounds.
J Chem Inf Model
; 58(8): 1544-1552, 2018 08 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-29953819
5.
Synthesis of five libraries of 6,5-fused heterocycles to establish the importance of the heterocyclic core for antiplasmodial activity.
Bioorg Med Chem
; 26(21): 5730-5741, 2018 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30391094
6.
Application of the Huisgen cycloaddition and 'click' reaction toward various 1,2,3-triazoles as HIV non-nucleoside reverse transcriptase inhibitors.
Bioorg Med Chem Lett
; 26(15): 3700-4, 2016 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27287366
7.
Novel indole sulfides as potent HIV-1 NNRTIs.
Bioorg Med Chem Lett
; 26(6): 1580-1584, 2016 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26876929
8.
Synthesis and in vitro growth inhibitory activity of novel silyl- and trityl-modified nucleosides.
Bioorg Med Chem
; 24(12): 2716-24, 2016 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27157005
9.
In vitro antiplasmodial activity of triazole-linked chloroquinoline derivatives synthesized from 7-chloro-N-(prop-2-yn-1-yl)quinolin-4-amine.
Bioorg Med Chem
; 23(15): 4163-4171, 2015 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26174655
10.
Covalent-Allosteric Kinase Inhibitors.
Angew Chem Int Ed Engl
; 54(35): 10313-6, 2015 Aug 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-26110718
11.
Novel indole based NNRTIs with improved potency against wild type and resistant HIV.
Bioorg Med Chem Lett
; 24(18): 4376-4380, 2014 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25176191
12.
C1,C2-ether derivatives of the Amaryllidaceae alkaloid lycorine: retention of activity of highly lipophilic analogues against cancer cells.
Bioorg Med Chem Lett
; 24(3): 923-7, 2014 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24393582
13.
Improved Rigidin-Inspired Antiproliferative Agents with Modifications on the 7-Deazahypoxanthine C7/C8 Ring Systems.
J Med Chem
; 2024 Jun 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38865195
14.
In search of a treatment for HIV--current therapies and the role of non-nucleoside reverse transcriptase inhibitors (NNRTIs).
Chem Soc Rev
; 41(13): 4657-70, 2012 Jul 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-22618809
15.
Discovery of 5'-Substituted 5-Fluoro-2'-deoxyuridine Monophosphate Analogs: A Novel Class of Thymidylate Synthase Inhibitors.
ACS Pharmacol Transl Sci
; 6(5): 702-709, 2023 May 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37200809
16.
Design and Optimization of Novel Competitive, Non-peptidic, SARS-CoV-2 Mpro Inhibitors.
ACS Med Chem Lett
; 14(10): 1434-1440, 2023 Oct 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37849558
17.
Covalent Allosteric Inhibitors of Akt Generated Using a Click Fragment Approach.
ChemMedChem
; 17(10): e202100776, 2022 05 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-35170857
18.
Imidazo[1,2-a]pyridin-3-amines as potential HIV-1 non-nucleoside reverse transcriptase inhibitors.
Bioorg Med Chem
; 19(14): 4227-37, 2011 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21700466
19.
In search of a cytostatic agent derived from the alkaloid lycorine: synthesis and growth inhibitory properties of lycorine derivatives.
Bioorg Med Chem
; 19(23): 7252-61, 2011 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22019045
20.
Accelerated Discovery of Potent Fusion Inhibitors for Respiratory Syncytial Virus.
ACS Infect Dis
; 6(5): 922-929, 2020 05 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32275393